A system and method for efficient transfer of data over a network. A data source and a destination are coupled to one another via a network. The data source is configured to transmit data to the destination and determine a network latency associated with the transmission. In response to determining a first transmission parameter may not be optimized, the source is configured to modify the first transmission parameter and evaluate its effect on data throughput. The source may repeat such modifications as long as throughput is increased. Once the first transmission parameter is deemed optimized, the source may perform a similar procedure for a second transmission parameter. In various embodiments, the first transmission parameter may correspond to a packet size and the second transmission parameter may correspond to a number of streams being processed by the source.