Invention Application
WO2003014732A1 APPARATUSES AND METHODS FOR CREATING AND TESTING PRE-FORMULATIONS AND SYSTEMS FOR SAME
审中-公开
用于创建和测试其预配制和系统的装置和方法
- Patent Title: APPARATUSES AND METHODS FOR CREATING AND TESTING PRE-FORMULATIONS AND SYSTEMS FOR SAME
- Patent Title (中): 用于创建和测试其预配制和系统的装置和方法
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Application No.: PCT/US2002/016962Application Date: 2002-05-24
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Publication No.: WO2003014732A1Publication Date: 2003-02-20
- Inventor: CARLSON, Eric, D. , CONG, Peijun , CHANDLER, William, H., Jr. , CHAU, Henry, K. , DANIELSON, Earl , DESROSIERS, Peter, J. , DOOLAN, Robert, D. , WU, Luping
- Applicant: SYMYX TECHNOLOGIES, INC. , CARLSON, Eric, D. , CONG, Peijun , CHANDLER, William, H., Jr. , CHAU, Henry, K. , DANIELSON, Earl , DESROSIERS, Peter, J. , DOOLAN, Robert, D. , WU, Luping
- Applicant Address: 3100 Central Expressway, Santa Clara, CA 95051 US
- Assignee: SYMYX TECHNOLOGIES, INC.,CARLSON, Eric, D.,CONG, Peijun,CHANDLER, William, H., Jr.,CHAU, Henry, K.,DANIELSON, Earl,DESROSIERS, Peter, J.,DOOLAN, Robert, D.,WU, Luping
- Current Assignee: SYMYX TECHNOLOGIES, INC.,CARLSON, Eric, D.,CONG, Peijun,CHANDLER, William, H., Jr.,CHAU, Henry, K.,DANIELSON, Earl,DESROSIERS, Peter, J.,DOOLAN, Robert, D.,WU, Luping
- Current Assignee Address: 3100 Central Expressway, Santa Clara, CA 95051 US
- Agency: HENDLER, Pablo, D.
- Priority: US60/311,332 20010810
- Main IPC: G01N33/48
- IPC: G01N33/48
Abstract:
The invention provides methods, apparatus, and systems for performing high-throughput preparation and screening of salts and polymporphs of drug candidates. The invention is directed towards enhancing the pre-formulation discovery process used for drug development. In particular, processes that determine suitable salts and processes that discover substantially every polymorph that can form from a particular drug candidate are provided. The processes are performed using several apparatuses that are specifically configured to carry-out various steps in a high-throughput characterization process. One such apparatus is configured for synthesizing a plurality of library members based on, for example, a library model generated by a computer system.
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