Invention Application
WO2007103694A2 TRIAZINE 11-BETA HYDROXYSTEROID DEHYDROGENASE TYPE I INHIBITORS
审中-公开
三氮嗪11-β羟基类固醇脱氢酶I型抑制剂
- Patent Title: TRIAZINE 11-BETA HYDROXYSTEROID DEHYDROGENASE TYPE I INHIBITORS
- Patent Title (中): 三氮嗪11-β羟基类固醇脱氢酶I型抑制剂
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Application No.: PCT/US2007063012Application Date: 2007-03-01
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Publication No.: WO2007103694A2Publication Date: 2007-09-13
- Inventor: LI JUN , ROBL JEFFREY A , KENNEDY LAWRENCE J
- Applicant: SQUIBB BRISTOL MYERS CO , LI JUN , ROBL JEFFREY A , KENNEDY LAWRENCE J
- Assignee: SQUIBB BRISTOL MYERS CO,LI JUN,ROBL JEFFREY A,KENNEDY LAWRENCE J
- Current Assignee: SQUIBB BRISTOL MYERS CO,LI JUN,ROBL JEFFREY A,KENNEDY LAWRENCE J
- Priority: US77815906 2006-03-01; US67989807 2007-02-28
Abstract:
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure: (I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein R 1 , R 2 and R 3 are defined herein.
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