公开(公告)号：AU2015296723B2

公开(公告)日：2020-12-24

申请号：AU2015296723

申请日：2015-07-28

Applicant: DOUGLAS SCIENTIFIC LLC

Inventor： COOK DARREN LYNN ,  JOHNSON ERIC GUY ,  WESTAD NATHAN LUTHER ,  HAUG ANDREW RICHARD ,  KONYNENBELT JAMES HENRY ,  MAASJO GRANT EDWARD ,  PATTERSON JARED WHITTIER ,  URKE BRENT CONRAD ,  ZITZMANN RYAN JOHN ,  SMITH CHAD STEVEN

IPC: G01N35/02

Abstract: An instrument for processing a biological sample includes a chassis. Connected to the chassis is a tape path along which a tape with a matrix of wells can be automatically advanced through the instrument, a dispensing assembly for dispensing the biological sample and a reagent into the matrix of wells of the tape to form a biological sample and reagent mixture, a sealing assembly for sealing the biological sample and reagent mixture in the tape, and an amplification and detection assembly for detecting a signal from the biological sample and reagent mixture in the matrix of wells in the tape.

公开(公告)号：AU2016238301A1

公开(公告)日：2017-10-05

申请号：AU2016238301

申请日：2016-03-25

Applicant: DOUGLAS SCIENTIFIC LLC

Inventor： MISCHE HANS ,  PEXSA GRANT ,  BAUMGARTNER MARK ,  HODGSON CORY ,  BRISTOW ANDREW ,  STECKELBERG JOHN ,  PATTERSON JARED

IPC: G01N33/48 ,  C12M1/34 ,  G01N21/63

Abstract: A modular testing device includes a base unit and an expansion unit that communicates with the base unit. The expansion unit includes a housing, a receptacle in which a sample holder containing a biological sample and reagent mixture can be placed, and an optical assembly positioned in the housing. The optical assembly is configured to amplify and detect a signal from the biological sample and reagent mixture. Data that is collected in the optical assembly is communicated to the base unit.

公开(公告)号：AU2014227758A1

公开(公告)日：2015-10-15

申请号：AU2014227758

申请日：2014-03-14

Applicant: DOUGLAS SCIENTIFIC LLC

Inventor： MISCHE HANS ALOIS ,  COOK DARREN LYNN

IPC: C12M1/34 ,  G01N15/06

Abstract: A system for processing and analyzing a sample includes a belt with wells that proceeds through the system, a dispensing station that dispenses the sample and reagents into the wells of the belt, and a detection station that detects an analyte in the wells of the belt. The system further includes a wash and decontamination station for decontaminating the wells of the belt.

公开(公告)号：AU2014205166B2

公开(公告)日：2017-10-12

申请号：AU2014205166

申请日：2014-01-13

Applicant: DOUGLAS SCIENTIFIC LLC

Inventor： WHALEN MARK ,  GERVAIS CHARLES ,  SANBORN ANTHONY ,  HAUG ANDREW ,  COOK DARREN ,  RAI SATISH ,  MISCHE HANS A ,  JUDICE STEPHEN A ,  SHAFFER DANIEL J

IPC: C12N15/09 ,  C12P19/34 ,  C12Q1/68 ,  G01N21/29 ,  G01N30/06 ,  G01N35/10

Abstract: A method for processing a biological material sample includes dispensing a sample into wells of an array tape from a sample plate, dispensing a reagent into the wells of the array tape from a reagent plate, and sealing the sample and the reagent in the array tape. The method further includes cooling the array tape and detecting biological material in the wells of the array tape.

公开(公告)号：AU2013214749B2

公开(公告)日：2017-05-11

申请号：AU2013214749

申请日：2013-02-04

Applicant: DOUGLAS SCIENTIFIC LLC

Inventor： WAGNER PAUL HOWARD ,  HAQ ADNANUL ,  SCHOENECK RICHARD JEROME

IPC: C12M1/34

Abstract: A high throughput biological sample processing system includes a sample carrier with a plurality of wells that progresses through the high throughput biological sample processing system. The system further includes a sample dispensing module, a reagent dispensing module, an accumulation/incubation module, and a detection module. The detection module employs an optical measuring device to encapsulate a biological sample in one of the plurality of wells of the sample carrier and detect energy from the chemistry of the biological sample to determine the amount of an analyte in the biological sample.

公开(公告)号：AU2015296723A1

公开(公告)日：2017-02-16

申请号：AU2015296723

申请日：2015-07-28

Applicant: DOUGLAS SCIENTIFIC LLC

Inventor： COOK DARREN LYNN ,  JOHNSON ERIC GUY ,  WESTAD NATHAN LUTHER ,  HAUG ANDREW RICHARD ,  KONYNENBELT JAMES HENRY ,  MAASJO GRANT EDWARD ,  PATTERSON JARED WHITTIER ,  URKE BRENT CONRAD ,  ZITZMANN RYAN JOHN ,  SMITH CHAD STEVEN

IPC: G01N35/02

Abstract: An instrument for processing a biological sample includes a chassis. Connected to the chassis is a tape path along which a tape with a matrix of wells can be automatically advanced through the instrument, a dispensing assembly for dispensing the biological sample and a reagent into the matrix of wells of the tape to form a biological sample and reagent mixture, a sealing assembly for sealing the biological sample and reagent mixture in the tape, and an amplification and detection assembly for detecting a signal from the biological sample and reagent mixture in the matrix of wells in the tape.

公开(公告)号：AU2014227738B2

公开(公告)日：2017-12-14

申请号：AU2014227738

申请日：2014-03-14

Applicant: DOUGLAS SCIENTIFIC LLC

Inventor： SCHOENECK RICHARD J ,  WAGNER PAUL H

IPC: G01N35/10 ,  B01L3/02 ,  G01N1/14

Abstract: A pipettor includes a wash chamber between an upper plate, a lower plate, an upper seal, and a lower seal. The upper and lower seal retain each other and are located between the upper and lower plates. The pipettor includes a gasket located below the lower plate, a pipette tip retained by the gasket, and a piston with a tapered tip that passes through the plates, seals, and gasket into the pipette tip. The upper and lower seal isolate the piston from the wash chamber. The pipettor includes a channel defined by the piston, extending into the pipette tip, and an actuator that advances and retracts the piston. When the actuator retracts the piston such that the piston loses sealing contact with the lower seal and the wash chamber is supplied with wash fluid and pressurized, wash fluid passes through the groove in the upper seal and into the channel.

公开(公告)号：EP2991767B1

公开(公告)日：2018-12-12

申请号：EP14791217.4

申请日：2014-05-01

Applicant: Douglas Scientific, LLC

Inventor： SMITH, Chad Steven ,  HENDRICKX, Jacob ,  MISCHE, Hans A.

IPC: B01L99/00 ,  B08B9/02 ,  B01L3/02 ,  B08B9/032 ,  G01N35/10

CPC classification number: B01L99/00 ,  B01L3/0275 ,  B01L2400/049 ,  B08B9/0323 ,  G01N35/1004

Abstract: A method of washing an array of pipette tips (94) with residual biological material includes lowering the array of pipette tips (94) into a wash basin (20) that includes an array of flush ports (22). A vacuum is generated such that the residual biological material in the array of pipette tips (94) is evacuated through the array of flush ports (22). A wash cycle is performed that includes raising the array of pipette tips (94) from the wash basin (20), filling the wash basin (20) with a primary wash fluid, lowering the array of pipette tips (94) into the wash basin (20), miming a pipette tip cleansing cycle, and generating a vacuum such that the primary wash fluid in the array of pipette tips (94) and the wash basin (20) is evacuated through the array of flush ports (22).

公开(公告)号：EP3055407A1

公开(公告)日：2016-08-17

申请号：EP14852273.3

申请日：2014-10-07

Applicant: Douglas Scientific, LLC

Inventor： BAUMGARTNER, Mark, B. ,  HODGSON, Cory, D. ,  BRISTOW, Andrew, L. ,  SYVERSON, Paul, A. ,  PEXSA, Grant, L. ,  DAVIS, Christopher, T. ,  SCHOENECK, Rich ,  BROWN, Duane ,  COOK, Darren

IPC: C12M1/34 ,  G01N21/64 ,  G01N21/63

CPC classification number: C12Q1/6848 ,  B01L3/50851 ,  B01L7/00 ,  B01L9/06 ,  B01L2200/10 ,  B01L2200/141 ,  B01L2300/021 ,  B01L2300/024 ,  B01L2300/025 ,  B01L2300/041 ,  B01L2300/0654 ,  G01N21/0332 ,  G01N21/253 ,  G01N21/6428 ,  G01N21/645 ,  G01N2021/0325 ,  G01N2021/6441 ,  G01N2021/6482 ,  G01N2201/0221 ,  G01N2201/0231

Abstract: A portable testing device includes a housing with an integrated touchscreen display and a receptacle in which a sample holder containing a biological sample and reagent mixture can be placed. The portable testing device further includes an optical assembly positioned in the housing, an electronic assembly that is configured to receive data from the optical assembly and transmit it for display on the touchscreen display, and a power supply in the housing to power the portable testing device. The optical assembly includes an excitation filter that extends across the entire optical assembly and an emission filter that extends across the entire optical assembly.

公开(公告)号：EP4007923A1

公开(公告)日：2022-06-08

申请号：EP20751636.0

申请日：2020-07-23

Applicant: Douglas Scientific, LLC

Inventor： WESTAD, Nathan Luther ,  HAUG, Andrew Richard

IPC: G01N35/10 ,  G01N35/00 ,  B01L3/02