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    READER DEVICE FOR LUMINESCENT IMMUNOASSAYS
    1.
    发明申请
    READER DEVICE FOR LUMINESCENT IMMUNOASSAYS 审中-公开
    用于发光免疫测定的读取装置

    公开(公告)号：WO2013014540A3

    公开(公告)日：2013-03-28

    申请号：PCT/IB2012001907

    申请日：2012-07-20

    Applicant: BIOSENSIA PATENTS LTD ,  MOYNIHAN SHANE ,  FLAVIN DIARMUID

    Inventor： MOYNIHAN SHANE ,  FLAVIN DIARMUID

    IPC: G01N21/64 ,  G01N3/44 ,  G01N33/53 ,  G01N33/543 ,  G01N33/58

    CPC classification number: G01N21/6486 ,  G01N21/278 ,  G01N21/645 ,  G01N21/6452 ,  G01N33/5302 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6441 ,  G01N2021/6471 ,  G01N2201/0624 ,  G01N2201/0627 ,  G01N2201/0648 ,  G01N2201/0693

    Abstract: The present disclosure, among other things, describes a reader system for analyzing one or more analytes in a fluid sample, comprising a casing (204) with at least one port (201) leading to a holster (301) which is configured to receive a cartridge (107) comprising a vertically oriented immunoassay device for analyzing one or more analytes in a fluid sample, an optical system (121) with excitation optics comprising a light source (302) and an excitation lens (305) configured to transmit light from the light source (302) and thereby excite a region of the vertically oriented immunoassay device when a cartridge (107) is placed in the holster (301), and collection optics comprising a photosensor (306) and a collection lens (307) configured to collect emitted light from the vertically oriented immunoassay device when a cartridge (107) is placed in the holster (301), an electromechanical motor system (106) configured to move the holster (301) in a vertical direction with respect to the optical system (121) so that the optical system (121) can interrogate different regions of the vertically oriented immunoassay device when a cartridge (107) is placed in the holster (301), and one or more digital processors (104a, 104b) and associated electronics configured to receive data from and control the optical system (121) and to control the electromechanical motor system (106).

    Abstract translation: 本公开尤其描述了一种用于分析流体样品中的一种或多种分析物的读取器系统，其包括具有至少一个通向皮套（301）的端口（201）的壳体（204），所述壳体被配置为接收 盒（107）包括用于分析流体样品中的一种或多种分析物的垂直取向的免疫测定装置，具有激发光学元件的光学系统（121），其包括光源（302）和激发透镜（305），所述光学系统被配置为透射来自 并且由此当盒（107）被放置在机架（301）中时激发垂直取向的免疫测定装置的区域，并且收集光学器件包括光电传感器（306）和收集透镜（307），其被配置为收集 当盒（107）被放置在机架（301）中时，来自垂直取向的免疫测定装置的光发射;机构电动机系统（106），被配置成相对于光学装置在垂直方向上移动机架 cal系统（121），使得当盒（107）被放置在机架（301）中时，光学系统（121）可以询问垂直定向的免疫测定装置的不同区域，以及一个或多个数字处理器（104a，104b）和 配置为从光学系统（121）接收数据和控制光学系统（121）并控制机电马达系统（106）的相关电子设备。

    FLOW CONTROL DEVICE FOR ASSAYS
    2.
    发明申请
    FLOW CONTROL DEVICE FOR ASSAYS 审中-公开
    用于测量的流量控制装置

    公开(公告)号：WO2011124991A3

    公开(公告)日：2011-12-29

    申请号：PCT/IB2011001473

    申请日：2011-04-06

    Applicant: BIOSENSIA PATENTS LTD ,  KRUGER JAN ,  WALSH JIM ,  MOYNIHAN SHANE ,  FLAVIN DIARMUID

    Inventor： KRUGER JAN ,  WALSH JIM ,  MOYNIHAN SHANE ,  FLAVIN DIARMUID

    IPC: B01L3/00

    CPC classification number: B01L3/5023 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2300/0636 ,  B01L2300/069 ,  B01L2300/0825 ,  B01L2300/0887 ,  B01L2400/0406 ,  B01L2400/0688 ,  Y10T29/494

    Abstract: The present disclosure relates to devices and methods for detecting the presence of a target analyte in a fluid sample using an assay. A fluidic device for flow control in an assay is disclosed comprising a water impermeable substrate (300) with a flow channel (301 ) located on its upper surface; a porous reagent pad (305) located within the flow channel, where the reagent pad includes a release zone that comprises a mobilizable reagent component of an assay; a porous sensor membrane (306) located within the flow channel downstream from the reagent pad, where the sensor membrane is separated from the reagent pad by a free space diffusion zone and where the sensor membrane includes a capture zone that comprises an immobilized capture component of the assay; a water impermeable top support located within the flow channel and disposed over at least a portion of the sensor membrane; and a flow control medium that forms a water impermeable seal around a portion of the top support and sensor membrane, where the seal is configure to direct flow of fluid into the sealed portion of the sensor membrane.

    Abstract translation: 本公开涉及使用测定法检测流体样品中目标分析物的存在的装置和方法。 公开了一种用于测定中的流量控制的流体装置，其包括具有位于其上表面上的流动通道（301）的不透水基底（300） 位于所述流动通道内的多孔试剂垫（305），其中所述试剂垫包括包含测定的可移动试剂组分的释放区; 位于试剂垫下游的流动通道内的多孔传感器膜（306），其中传感器膜通过自由空间扩散区与试剂垫隔开，并且其中传感器膜包括捕获区，捕获区包含固定的捕获组分 测定; 位于所述流动通道内并设置在所述传感器膜的至少一部分上方的不透水的顶部支撑件; 以及流动控制介质，其围绕所述顶部支撑件和传感器膜的一部分形成不透水的密封件，其中所述密封件构造成将流体的流动引导到所述传感器膜的所述密封部分中。

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