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1.发明公开NON-INVASIVE METHOD AND MEANS FOR -i(IN-VIVO) BONE-GROWTH STIMULATION. 失效VERFAHREN UND VORRICHTUNG ZUR NICHTINVASIVEN在体内的KNOCHENWACHSTUMSSTIMULATION。
公开(公告)号：EP0642331A4
公开(公告)日：1995-06-14
申请号：EP93914177
申请日：1993-05-26
Applicant: MCLEOD KENNETH J , RUBIN CLINTON T
Inventor： MCLEOD KENNETH J , RUBIN CLINTON T
CPC classification number: A61F2/28 , A61B17/58 , A61F2002/286 , A61H1/005 , A61H1/006 , A61H23/00 , A61H23/0218 , A61H2023/0209 , A61H2201/502 , A61H2203/04 , A61N7/00
Abstract: An apparatus for preventing osteopenia, promoting bone tissue growth, ingrowth, and healing of bone tissue includes at least one rigid plate (11, 12, 31, 40, 42, 47, 50, 53, 70, 71) to support the living body, a stiffly compliant structure (13, 14, 41, 48, 48', 51, 76) engaged to the at least one plate, a dynamic force transducer (15, 15', 38, 38', 44, 44', 54, 77) engaged to the plate to vertically drive the plate. The stiffly compliant structure having a spring constant such that, in the context of the total of the mass of the plate and the mass of the plated-supported body mass, the total mass and the compliant structure exhibit a naturally resonant frequency in the range of 10 Hz to 100 Hz.
Abstract translation: 一种用于预防骨质减少，促进骨组织生长，向内生长和骨组织愈合的装置，包括至少一个刚性板（11,12,31,40,42,47,50,53,70,71）以支撑活体 ，与所述至少一个板接合的刚性柔顺结构（13,14,41,48,48'，51,76），动态力转换器（15,15'，38,38'，44,44'，54 ，77）与板接合以垂直驱动板。 刚性柔顺结构具有弹簧常数，使得在板的质量和电镀支撑体质量的总和的情况下，总质量和柔性结构呈现出自然谐振频率，其范围为 10赫兹到100赫兹。
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公开(公告)号：EP0642331A1
公开(公告)日：1995-03-15
申请号：EP93914177.0
申请日：1993-05-26
Applicant: McLEOD, Kenneth, J. , RUBIN, Clinton, T.
Inventor： McLEOD, Kenneth, J. , RUBIN, Clinton, T.
CPC classification number: A61F2/28 , A61B17/58 , A61F2002/286 , A61H1/005 , A61H1/006 , A61H23/00 , A61H23/0218 , A61H2023/0209 , A61H2201/502 , A61H2203/04 , A61N7/00
Abstract: An apparatus for preventing osteopenia, promoting bone tissue growth, ingrowth, and healing of bone tissue includes at least one rigid plate (11, 12, 31, 40, 42, 47, 50, 53, 70, 71) to support the living body, a stiffly compliant structure (13, 14, 41, 48, 48', 51, 76) engaged to the at least one plate, a dynamic force transducer (15, 15', 38, 38', 44, 44', 54, 77) engaged to the plate to vertically drive the plate. The stiffly compliant structure having a spring constant such that, in the context of the total of the mass of the plate and the mass of the plated-supported body mass, the total mass and the compliant structure exhibit a naturally resonant frequency in the range of 10 Hz to 100 Hz.
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公开(公告)号：EP0642331B1
公开(公告)日：2001-01-24
申请号：EP93914177.6
申请日：1993-05-26
Applicant: McLEOD, Kenneth, J. , RUBIN, Clinton, T.
Inventor： McLEOD, Kenneth, J. , RUBIN, Clinton, T.
IPC: A61H1/00
CPC classification number: A61F2/28 , A61B17/58 , A61F2002/286 , A61H1/005 , A61H1/006 , A61H23/00 , A61H23/0218 , A61H2023/0209 , A61H2201/502 , A61H2203/04 , A61N7/00
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公开(公告)号：PT642331E
公开(公告)日：2001-06-29
申请号：PT93914177
申请日：1993-05-26
Applicant: MCLEOD KENNETH J , RUBIN CLINTON T
Inventor： MCLEOD KENNETH J , RUBIN CLINTON T
Abstract: A method and apparatus for preventing osteopenia, promoting bone tissue growth, ingrowth, and healing of bone tissue includes the step of and means for applying a mechanical load to the bone tissue at a relatively low level on the order of between about 50 and about 500 microstrain, peak-to-peak, and at a relatively high frequency in the range from about 10 and about 100 Hz. Mechanical loading at such strain levels and such frequencies has been found to prevent bone loss and enhance new bone formation.
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公开(公告)号：ES2155451T3
公开(公告)日：2001-05-16
申请号：ES93914177
申请日：1993-05-26
Applicant: MCLEOD KENNETH J , RUBIN CLINTON T
Inventor： MCLEOD KENNETH J , RUBIN CLINTON T
Abstract: A method and apparatus for preventing osteopenia, promoting bone tissue growth, ingrowth, and healing of bone tissue includes the step of and means for applying a mechanical load to the bone tissue at a relatively low level on the order of between about 50 and about 500 microstrain, peak-to-peak, and at a relatively high frequency in the range from about 10 and about 100 Hz. Mechanical loading at such strain levels and such frequencies has been found to prevent bone loss and enhance new bone formation.
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Patent Agency Ranking
公开(公告)号：CA2136012C
公开(公告)日：2004-05-04
申请号：CA2136012
申请日：1993-05-26
Applicant: MCLEOD KENNETH J , RUBIN CLINTON T
Inventor： MCLEOD KENNETH J , RUBIN CLINTON T
Abstract: An apparatus for preventing osteopenia, promoting bone tis- sue growth, ingrowth, and healing of bone tissue includes at least one rigid plate (11, 12, 31, 40, 42, 47, 50, 53, 70, 71) to support the living body, a stiffly compliant structure (13, 14, 41, 48, 48', 51, 76) engaged to the at least one plate, a dynamic force transducer (15, 15', 38, 38', 44, 44', 54, 77) engaged to the plate to vertically drive the plate. The stiffly compliant structure having a spring constant such that, in the context of the total of the mass of the plate and the mass of the plated-supported body mass, the total mass and the compliant structure exhibit a naturally resonant frequency in the range of 10 Hz to 100 Hz. (See formula I)
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公开(公告)号：DE69329895T2
公开(公告)日：2001-05-03
申请号：DE69329895
申请日：1993-05-26
Applicant: MCLEOD KENNETH J , RUBIN CLINTON T
Inventor： MCLEOD KENNETH J , RUBIN CLINTON T
Abstract: A method and apparatus for preventing osteopenia, promoting bone tissue growth, ingrowth, and healing of bone tissue includes the step of and means for applying a mechanical load to the bone tissue at a relatively low level on the order of between about 50 and about 500 microstrain, peak-to-peak, and at a relatively high frequency in the range from about 10 and about 100 Hz. Mechanical loading at such strain levels and such frequencies has been found to prevent bone loss and enhance new bone formation.
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公开(公告)号：DE69329895D1
公开(公告)日：2001-03-01
申请号：DE69329895
申请日：1993-05-26
Applicant: MCLEOD KENNETH J , RUBIN CLINTON T
Inventor： MCLEOD KENNETH J , RUBIN CLINTON T
Abstract: A method and apparatus for preventing osteopenia, promoting bone tissue growth, ingrowth, and healing of bone tissue includes the step of and means for applying a mechanical load to the bone tissue at a relatively low level on the order of between about 50 and about 500 microstrain, peak-to-peak, and at a relatively high frequency in the range from about 10 and about 100 Hz. Mechanical loading at such strain levels and such frequencies has been found to prevent bone loss and enhance new bone formation.
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公开(公告)号：AT198828T
公开(公告)日：2001-02-15
申请号：AT93914177
申请日：1993-05-26
Applicant: MCLEOD KENNETH J , RUBIN CLINTON T
Inventor： MCLEOD KENNETH J , RUBIN CLINTON T
Abstract: A method and apparatus for preventing osteopenia, promoting bone tissue growth, ingrowth, and healing of bone tissue includes the step of and means for applying a mechanical load to the bone tissue at a relatively low level on the order of between about 50 and about 500 microstrain, peak-to-peak, and at a relatively high frequency in the range from about 10 and about 100 Hz. Mechanical loading at such strain levels and such frequencies has been found to prevent bone loss and enhance new bone formation.
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公开(公告)号：AU4393393A
公开(公告)日：1993-12-30
申请号：AU4393393
申请日：1993-05-26
Applicant: MCLEOD KENNETH J , RUBIN CLINTON T
Inventor： MCLEOD KENNETH J , RUBIN CLINTON T
Abstract: A method and apparatus for preventing osteopenia, promoting bone tissue growth, ingrowth, and healing of bone tissue includes the step of and means for applying a mechanical load to the bone tissue at a relatively low level on the order of between about 50 and about 500 microstrain, peak-to-peak, and at a relatively high frequency in the range from about 10 and about 100 Hz. Mechanical loading at such strain levels and such frequencies has been found to prevent bone loss and enhance new bone formation.
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