公开(公告)号：WO9110887A3

公开(公告)日：1991-08-22

申请号：PCT/GB9100059

申请日：1991-01-16

Applicant: NAT RES DEV

Inventor： BUTLER CLIVE ,  SHAMS IDEN

IPC: G01B5/00 ,  G01B5/012 ,  G01B5/20 ,  G01B11/00 ,  G01K13/00 ,  A61B5/00 ,  G01K1/02 ,  H04M11/00

CPC classification number: G01B11/007 ,  G01B5/012

Abstract: A probe for position-determining apparatus and the like having a housing (10) and in the housing a sensing space and an aperture (16) to the sensing space, a stylus (40) extending out of the sensing space through said aperture, a stylus-support means (14) at said aperture and means (20) for constraining said stylus in to low-friction engagement (43, 50) with said support means and generally towards a neutral axis while permitting position-determining displacement on said support means and in which the stylus is linked to the constraining means through a lever arrangement including a first lever element (21) extending sideways from and around said stylus and a second lever (22) from said first lever to transfer stylus displacement to said constraining means and constraint from said constraining means to said stylus, said lever arrangement including an abutment (15) engageable by said second lever.

公开(公告)号：WO8604234A3

公开(公告)日：1986-09-12

申请号：PCT/GB8600028

申请日：1986-01-16

Applicant: NAT RES DEV ,  SENIOR JUDITH ,  TROUGHTON KAY MARIE

Inventor： SENIOR JUDITH ,  TROUGHTON KAY MARIE

IPC: C07C281/06 ,  A61K31/175 ,  A61K31/557 ,  C07C67/00 ,  C07C239/00 ,  C07C313/00 ,  C07C323/44 ,  C07C325/00 ,  C07C337/06 ,  C07C405/00 ,  C07D493/00

CPC classification number: C07C405/0091 ,  A61K31/175 ,  A61K31/557

Abstract: Compounds having thromboxane antagonist activity are of use in the treatment of hormone-dependent neoplasias for example oestrogen-dependent neoplasias. Thromboxane antagonists of particular value are compounds of formula (I) wherein formula (II) represents one of the divalent cyclic groups (III). The letters a and b indicating in each case the points of attachment of the substituents R1 and CV(R2)-NV'R, respectively; R1 is a 6-carboxyhex-2-enyl group or a modification thereof in which the group is altered by one, or an appropriate combination of two or more, of the following: (a) alteration of the position of the double bond, (b) reduction of the double bond, (c) alteration of the chain length through a decrease of one or two methylene groups or an increase of one to six methylene groups, (d) replacement of one or two methylene groups each separately by an oxygen or sulphur atom with the proviso that in the modified group no oxygen or sulphur atom is in an alpha position relative to either a doubly bonded carbon atom or to the carboxy group or a derivative thereof and that at least 2 carbon atoms separate any pair of oxygen and/or sulphur atoms; and (e) formation of an amide, ester or salt derivative of the carboxy groups; V and V' either each separately is hydrogen or together are the second bond of a carbon-nitrogen double bond; R2 is hydrogen, an aliphatic hydrocarbon group or an aliphatic hydrocarbon group substituted by an aromatic group directly or through an oxygen or sulphur atom; and R is a group -NH.CO.NH-R3 or -NH.CS.NH-R3 wherein R3 is an aliphatic hydrocarbon group, an aromatic group or an aliphatic hydrocarbon group substituted by one or more aromatic groups directly or through an oxygen or sulphur atom.

公开(公告)号：WO8600538A3

公开(公告)日：1986-03-13

申请号：PCT/GB8500313

申请日：1985-07-12

Applicant: NAT RES DEV ,  GRAHAM NEIL BONNETTE ,  MCNEILL MARION EILEEN

Inventor： GRAHAM NEIL BONNETTE ,  MCNEILL MARION EILEEN

IPC: G12B1/00 ,  A61K9/00 ,  A61K9/20 ,  A61L2/28 ,  A61M31/00 ,  C08G18/48 ,  C08G65/32 ,  C08L71/02 ,  A61K9/22

CPC classification number: C08G18/4833 ,  A61K9/0039 ,  A61K9/0041 ,  A61K9/2031 ,  A61L2/28 ,  A61M31/002 ,  C08G2250/00

Abstract: A temperature- and/or polar fluid-sensitive device which comprises a mechanically strained semi-crystalline hydrophilic polymer.

公开(公告)号：WO1982004442A1

公开(公告)日：1982-12-23

申请号：PCT/GB1982000183

申请日：1982-06-18

Applicant: NAT RES DEV ,  STANGROOM JAMES EDWARD

Inventor： NAT RES DEV

IPC: C10M01/08

CPC classification number: C10M171/001 ,  C07C17/12 ,  C08K5/0008 ,  C07C25/18 ,  C08L5/00 ,  C08L33/00

Abstract: Fluides electrovisqueux (EV) se composant de particules hydrophiles solides dispersees dans des liquides hydrophobes, le liquide contenant un composant de derives de diaryle correspondant a la formule generale I: (FORMULE) dans laquelle R represente CY2, O, S, SO, SO2, SiF2, ou O-SiY2-O, Y1 et X2 sont des halogenes, (m + n) est compris entre 1 et 3 en moyenne, et (p + q) est compris entre 0 et 1 en moyenne. Les fluides EV contenant ces nouveaux composants possedent generalement des proprietes ameliorees en ce qui concerne les viscosites inferieures, les conductivites electriques, les toxicites et les points de congelation. Dans un mode de realisation preferentielle, le composant est un melange de diphenylmethanes bromes dans lequel R represente CH2, n = 0, X1 = Br, (m + n) est approximativement 1, et (p + q) = 0.

公开(公告)号：WO1982004249A1

公开(公告)日：1982-12-09

申请号：PCT/GB1982000156

申请日：1982-05-28

Applicant: NAT RES DEV ,  DAWSON GLENN WILLIAM ,  GRIFFITHS DAVID CLIFFORD ,  PICKETT JOHN ANTHONY

Inventor： NAT RES DEV

IPC: C07C61/35

CPC classification number: C07C403/02 ,  A01N49/00 ,  A01N57/36 ,  C07B2200/09 ,  C07C1/24 ,  C07C61/35 ,  C07C63/34 ,  C07C2521/04 ,  C07C2601/16 ,  C07D209/48 ,  C07D237/04 ,  C07D333/48 ,  C07C11/21

Abstract: Compounds of the formula: wherein A represents the residue of the dienophile, obtainable as a Diels-Alder adduct of beta-farnesene and a dienophile, which are used in pest control, or which are converted to a derivative of said adduct before use in pest control, particularly in the control of aphides.

Abstract translation: 下式的化合物：其中A表示亲二烯残基，可作为β-法呢烯和亲二烯体的Diels-Alder加合物获得，其用于病虫害防治中，或者被转化为所述加合物的衍生物 用于病虫害防治，特别是控制蚜虫。

公开(公告)号：WO1982000206A1

公开(公告)日：1982-01-21

申请号：PCT/GB1981000105

申请日：1981-06-19

Applicant: NAT RES DEV CORP ,  SHANKS I

Inventor： NAT RES DEV CORP

IPC: G01R13/40

CPC classification number: G01R13/408 ,  G02F1/134336

Abstract: Deux traces de signaux sont affichees simultanement par un affichage electro-optique tel qu'un affichage a cristaux liquides. L'affichage peut avoir un format cartesien possedant m electrodes X et n electrodes Y, les electrodes X possedant dans ce cas une forme en bande tandis que chaque electrode Y comprend deux ou plusieurs composants Ya, Yb interfolies. Chaque intersection XY peut ainsi etre adressee au moyen d'une tension 0 en XYa, ou XYb avec des tensions superieures au seuil partout ailleurs. Une serie de n formes d'ondes codees differentes sont produites et chaque forme differente est appliquee a chaque electrode X. Les deux traces sont echantillonnees et converties en valeurs d'echantillons numeriques. Des formes d'ondes codees sont produites et appliquees a chaque electrode Ya Yb simultanement a celles appliquees aux electrodes X; les codes produits sont selectionnes a partir des m codes differents et se referent a la position des electrodes Y et a la valeur de l'echantillon a afficher. Les formes d'ondes codees peuvent etre des codes binaires tels que des codes pseudoaleatoires. Un encodeur de priorite attribue une priorite aux valeurs d'echantillons des deux signaux de traces.

公开(公告)号：WO1981002789A1

公开(公告)日：1981-10-01

申请号：PCT/GB1981000045

申请日：1981-03-13

Applicant: NAT RES DEV CORP ,  JOHNSON G ,  EDELSTEIN W ,  HUTCHISON J ,  MALLARD J ,  REDPATH T

Inventor： NAT RES DEV CORP

IPC: G01N24/08

CPC classification number: G01R33/482 ,  G01R33/5615 ,  G01R33/5616

Abstract: To produce image information from an object it is subjected to a continuous static magnetic field along a Z axis and to sets of sequences of gradient G u, G u and G u to the magnetic field. Spins in a selected plane (the X-Z plane) are excited by selective rf pulses of an associated G u gradient and the selected spins are subjected to a reversed G u gradient together with a G u gradient. The G u gradient is then switched off and the direction of the G u gradient is then repeatedly reversed. During the action of reversal of the G u gradient a small G u gradient is provided. Each reversed G u gradient is held constant for a sufficient time for a free induction decay signal to be generated thus providing a multiple echo of the spins in the selected plane. Alternate signals are time-reversed and then both the time-reversed and non time-reversed signals are subject to Fourier transformation.

Abstract translation: 为了从物体产生图像信息，它沿Z轴经受连续的静磁场，并且对磁场进行梯度G u，G u和G u u的序列的集合。 在选定的平面（X-Z平面）中的旋转被相关联的G uu梯度的选择性rf脉冲激发，并且所选择的自旋与G u u u梯度一起受到反转的G uu梯度。 然后将G uu u梯度关闭，然后G ux u梯度的方向重复反向。 在反转G ux u梯度的作用下，提供了一个小的G u梯度。 每个反转的G u u u梯度保持恒定足够的时间以产生自由感应衰减信号，从而在所选择的平面中提供自旋的多个回波。 交替信号是时间反转的，然后时间反转信号和非时间反相信号都进行傅里叶变换。

公开(公告)号：WO1981002788A1

公开(公告)日：1981-10-01

申请号：PCT/GB1981000044

申请日：1981-03-13

Applicant: NAT RES DEV CORP ,  EDELSTEIN W ,  HUTCHISON J ,  MALLARD J ,  JOHNSON G ,  REDPATH T

Inventor： NAT RES DEV CORP

IPC: G01N24/08

CPC classification number: G01R33/482 ,  G01R33/5615 ,  G01R33/5616

Abstract: To produce image information from an object it is subjected to a continuous static magnitic field along a Z axis and to sets of sequences of orthogonal gradients Gx, Gy and Gz to the magnetic field. Spins in a selected plane (the X-Z plane) are excited by selective rf pulses and an associated Gy gradient and the selected spins are subjected to all three gradients of which the Gz gradient provides twist or warp to each column of spins extending along the Z axis to phaseencode the columns. The spin-echo signals are read out in the presence of a Gx gradient. In each set of sequences a different value of Z gradient is employed. The Fourier transformed spin-echo signals obtained from each sequence, when arranged in order of increasing Gz gradient and subjected to a second Fourier transform represent the distribution of spin density in the Z direction, thus giving a two-dimensional image of the selected X-Z plane.

公开(公告)号：WO1981002502A1

公开(公告)日：1981-09-03

申请号：PCT/GB1981000018

申请日：1981-02-12

Applicant: NAT RES DEV CORP ,  GERZON M

Inventor： NAT RES DEV CORP

IPC: H04S03/02

CPC classification number: H04S3/02 ,  H04S2420/11

Abstract: Decoder for feeding an irregular array of m (being three or more) pairs of diametrically opposite loudspeakers, each loudspeaker being disposed at an equal distance r from a common reference point. The decoder incorporates a WXY circuit (10) for producing output signals (W, X, Y and -jW) from the input signals, and shelf filters (12, 14, 16 and 22) and high-pass filters (18, 20 and 24) for producing output signals (W', X', Y' and -jW//c). In addition the decoder includes an amplitude matrix circuit (26) which is such that the sum of the signals (S//c and S//c fed to the loudspeakers of each pair is the same of all pairs of loudspeakers and (FORMULA) where (FORMULA) M being the 2 x m matrix (FORMULA) K being the mx 2 matrix (FORMULA) I being the 2 x 2 identity matrix, and X being a positive real constant which may be frequency dependent. A decoder is also provided for feeding a three-dimensional loudspeaker layout. Thus the outputs of the loudspeakers may be adapted to irregular positioning of the loudspeakers which may be dictated by room geometry.

Abstract translation: 用于馈送m（三个或更多）对直径相对的扬声器的不规则阵列的解码器，每个扬声器以与公共参考点相等的距离r设置。 解码器包括用于从输入信号产生输出信号（W，X，Y和-jW）的WXY电路（10），以及搁板滤波器（12,14,16和22）和高通滤波器（18,20和 24），用于产生输出信号（W'，X'，Y'和-jW // c）。 此外，解码器包括幅度矩阵电路（26），其使得馈送到每对扬声器的信号（S // c和S // c）的总和与所有扬声器对相同，并且（公式） 其中（公式）M是2×m矩阵（公式）K是m×2矩阵（公式），I是2×2单位矩阵，X是可能是频率依赖性的正实常数，解码器还用于 馈送三维扬声器布局，因此扬声器的输出可以适应扬声器的不规则定位，这可以由房间几何形状决定。

公开(公告)号：WO1980000313A1

公开(公告)日：1980-03-06

申请号：PCT/GB1979000122

申请日：1979-07-19

Applicant: NAT RES DEV CORP ,  CLARK J

Inventor： NAT RES DEV CORP

IPC: B01J33/00

CPC classification number: C07C205/45 ,  B01J27/00 ,  B01J33/00 ,  B01J37/0219 ,  C07B39/00 ,  C07C17/208 ,  C07C45/68 ,  C07C49/675 ,  C07C205/12 ,  C07C49/782

Abstract: Stabilisation against water uptake of hygroscopic salts useful as catalysts by formation of anhydrous adducts with particulate support materials in order to facilitate manipulation and storage. The adducts comprise a particulate support material and a hygroscopic salt of a species of formula R sR sR sR sN, R sR sR sR sP, R sR sR sR sAs, wherein R1-R4 which may be identical or different represent hydrogen or alkyl or aryl groups, or of Li, Na, K, Rb, Cs, Be, Mg, Ca, Sr, Ba, Cu, Ag, Zn, Cd, Au, Hg, Ga, In, Tl, Sn, Sb or Pb, the salt anion being fluoride, bromide, chloride, sulphate, nitrate, nitrite, cyanate, thiocyanate, peroxide, hydroxide, acetate, formate or comprises phosphorus and oxygen, the salt being coated on the support material thereby being rendered less hygroscopic; provided that when the species is Na, the anion is other than hydroxide and when the species is Tl the anion is fluoride, bromide or chloride. Adducts of salts useful in catalytic fluorination, e.g. R sR sR sR sN sF s and CsF are of especial interest.

Abstract translation: 通过与颗粒状载体材料形成无水加合物，以便于操作和储存，可用作催化剂的吸湿盐水的吸收稳定。 加合物包含颗粒状载体材料和具有式R s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s sP，R s s s s s s s s s s s s s s s其中可以相同或不同的R 1 -R 4表示氢或烷基或芳基，或者Li，Na，K，Rb，Cs， Be，Mg，Ca，Sr，Ba，Cu，Ag，Zn，Cd，Au，Hg，Ga，In，Tl，Sn，Sb或Pb，盐阴离子为氟，溴，氯，硫酸根，硝酸根，亚硝酸根， 氰酸盐，硫氰酸盐，过氧化物，氢氧化物，乙酸盐，甲酸盐或包含磷和氧，所述盐被涂覆在载体材料上，从而变得较少吸湿性; 条件是当物种为Na时，阴离子不是氢氧化物，当物质为T1时，阴离子是氟化物，溴化物或氯化物。 用于催化氟化的盐的加合物，例如 特别感兴趣的是，S sR sR sN s + sF s-s和CsF。