公开(公告)号：WO1997040388A1

公开(公告)日：1997-10-30

申请号：PCT/JP1997001394

申请日：1997-04-23

Applicant: SHISEIDO COMPANY, LTD. ,  THE GENERAL HOSPITAL CORPORATION

Inventor： SHISEIDO COMPANY, LTD. ,  THE GENERAL HOSPITAL CORPORATION ,  MORO, Osamu ,  WAKITA, Kawori ,  HYOCHI, Manami ,  LERNER, Ethan, A. ,  TAJIMA, Masahiro

IPC: G01N33/68

CPC classification number: G01N33/6842 ,  A61K38/00 ,  C07K14/47 ,  C07K14/57563 ,  G01N33/68

Abstract: This specification relates to use of peptides having a specific affinity to subtype 1 of PACAP (pituitary adenylate cyclase activating polypeptide) receptors, particularly MAX (67 amino acids), NSP (61 amino acids) and M 65 (46 amino acids). MAX and NSP act as agonists to PACAP type 1 receptors, and M 65 acts as an antagonist to PACAP type 1 receptors.

Abstract translation: 本说明书涉及对PACAP（垂体腺苷酸环化酶活化多肽）受体，特别是MAX（67个氨基酸）NSP（61个氨基酸）和M65（46个氨基酸）亚型具有特异性亲和力的肽的用途。 MAX和NSP作为PACAP 1型受体的激动剂，M65作为PACAP 1型受体的拮抗剂。

公开(公告)号：WO1997002090A1

公开(公告)日：1997-01-23

申请号：PCT/JP1996001803

申请日：1996-06-28

Applicant: SHISEIDO COMPANY, LTD. ,  WATANABE, Kei ,  KAKOKI, Hiroyuki ,  ITO, Kenzo

Inventor： SHISEIDO COMPANY, LTD.

IPC: B01F17/52

CPC classification number: B01F17/0028 ,  A61K8/06 ,  A61K8/342 ,  A61K8/585 ,  A61K8/8152 ,  A61K8/891 ,  A61K2800/33 ,  A61Q19/00

Abstract: An emulsion composition comprising (i) an alkyl modified carboxyvinyl polymer, (ii) a C12-C28 higher alcohol that is solid at room temperature (e.g., 15 to 20 DEG C), and (iii) a silicone oil, wherein the (i) to (ii) ratio is 0.5 or below by weight.

Abstract translation: 一种乳液组合物，其包含（i）烷基改性的羧基乙烯基聚合物，（ii）在室温（例如15至20℃）下为固体的C 12 -C 28高级醇，和（iii）硅油，其中（i ）至（ii）的比例为0.5重量％以下。

公开(公告)号：WO1996003107A1

公开(公告)日：1996-02-08

申请号：PCT/JP1995001445

申请日：1995-07-20

Applicant: SHISEIDO COMPANY, LTD. ,  IKEDA, Tomoko ,  AIZAWA, Masanori

Inventor： SHISEIDO COMPANY, LTD.

IPC: A61K07/00

CPC classification number: A61K8/361 ,  A61K8/06 ,  A61K8/062 ,  A61K8/37 ,  A61K8/44 ,  A61K8/585 ,  A61Q1/02 ,  A61Q1/06 ,  Y10S514/937 ,  Y10S514/938

Abstract: A cosmetic composition comprising water, a waxy ester of a C18-C34 fatty acid with a C18-C44 higher alcohol, and at least one component usable in cosmetics, including an amphoteric surfactant, and optionally containing a C18-C34 higher fatty acid itself. The invention can provide an intermediate composition for cosmetics, such as foundation, lipstick or eye shadow, which are mild to the touch and have such physical and chemical characteristics as to permit stable preservation.

Abstract translation: 一种化妆品组合物，其包含水，C18-C34脂肪酸的蜡状酯与C18-C44高级醇，以及至少一种可用于化妆品的成分，包括两性表面活性剂，以及任选含有C18-C34高级脂肪酸本身的化妆品组合物。 本发明可以提供一种化妆品的中间组合物，例如基础，口红或眼影，其触感温和，具有允许稳定保存的物理和化学特性。

公开(公告)号：WO1992010178A1

公开(公告)日：1992-06-25

申请号：PCT/JP1991001703

申请日：1991-12-11

Applicant: SHISEIDO COMPANY, LTD. ,  TAGUCHI, Shigeru ,  INOKUCHI, Miwako ,  NAKAJIMA, Noriko ,  INOMATA, Mie ,  NAITOH, Yasuo

Inventor： SHISEIDO COMPANY, LTD.

IPC: A61K31/315

CPC classification number: A61Q17/00 ,  A61K8/27 ,  A61K8/44 ,  A61K31/195 ,  A61K31/315 ,  A61K31/405 ,  A61K31/415 ,  A61K2800/75

Abstract: An antipruritic drug comprising a zinc-amino acid conjugate and an antipruritic composition containing 2.6 x 10-3 to 2.6 x 10-1M of said drug.

公开(公告)号：WO1991004279A1

公开(公告)日：1991-04-04

申请号：PCT/JP1990001168

申请日：1990-09-12

Applicant: SHISEIDO COMPANY LTD. ,  AKASAKA, Hidemichi ,  YAMAGUCHI, Toshijiro

Inventor： SHISEIDO COMPANY LTD.

IPC: C08B37/08

CPC classification number: C08B37/0072

Abstract: A process for producing hyaluronic acid having a viscosity average molecular weight of 500,000 or less by mechanically degradating a high molecular hyaluronic acid solution by a shear treatment.

Abstract translation: 通过剪切处理机械降解高分子量透明质酸溶液来制造粘均分子量为500,000以下的透明质酸的方法。

公开(公告)号：WO1991002790A1

公开(公告)日：1991-03-07

申请号：PCT/JP1990001036

申请日：1990-08-14

Applicant: SHISEIDO COMPANY, LTD. ,  IIDA, Toshii ,  KAMINUMA, Toshihiko ,  FUSE, Yuka ,  TAJIMA, Masahiro ,  YANAGI, Mitsuo ,  OKAMOTO, Hiroshi ,  KISHIMOTO, Jiro ,  IFUKU, Ohji ,  KATO, Ichiro

Inventor： SHISEIDO COMPANY, LTD.

IPC: C12N09/02

CPC classification number: C12N9/0071 ,  C07K1/107 ,  C12Y114/17003 ,  Y10S435/814 ,  Y10S435/815

Abstract: An enzyme which acts on a peptide C-terminal/glycine adduct of formula (I), (wherein A represents a residue formed by removing an alpha -amino or imino group and an alpha -carboxyl group from a natural alpha -amino acid, and X represents a hydrogen atom or a residue of an amino acid derivative which combines with the N atom via a carbonyl group) to produce a peptide C-terminal/ alpha -hydroxyglycine adduct of formula (II), (wherein A and X are each as defined above), and another enzyme which acts on the compound of formula (II) to produce a C-terminal amidated peptide of formula (III), wherein A and X are each as defined above.

Abstract translation: 作用于式（I）的肽C-末端/甘氨酸加合物的酶（其中A表示通过从天然α-氨基酸除去α-氨基或亚氨基和α-羧基形成的残基，以及 X表示氢原子或通过羰基与N原子结合的氨基酸衍生物的残基），以制备式（II）的肽C-末端/α-羟基甘氨酸加合物（其中A和X各自为 以及另一种作用于式（II）化合物以产生式（III）的C-末端酰胺化肽的酶，其中A和X各自如上所定义。

公开(公告)号：WO1989012096A1

公开(公告)日：1989-12-14

申请号：PCT/JP1989000521

申请日：1989-05-25

Applicant: SHISEIDO COMPANY LTD. ,  IIDA, Toshii ,  FUSE, Yuka ,  TAJIMA, Masahiro ,  YANAGI, Mitsuo ,  OKAMOTO, Hiroshi

Inventor： SHISEIDO COMPANY LTD.

IPC: C12N09/02

CPC classification number: C12N9/0071 ,  C07K1/107 ,  C12Y114/17003

Abstract: A C-terminus amidation enzyme composition of serum or blood plasma origin, which acts on a C-terminus glycine adduct represented by formula (I) (wherein A represents a residue other than alpha-amino or imino group and alpha-carboxyl group of a natural alpha-amino acid origin, and X represents a hydrogen atom or a residue of an amino acid derivative bound to the N atom via a carbonyl group) to produce a C-terminus amidation product represented by formula (II) (wherein A and X are as defined above) and glyoxylic acid, is disclosed. A process for preparing the composition and its use are also disclosed.

公开(公告)号：WO1989004365A1

公开(公告)日：1989-05-18

申请号：PCT/JP1988001124

申请日：1988-11-07

Applicant: SHISEIDO COMPANY LTD. ,  HAZE, Shinichiro ,  IFUKU, Ohji ,  KISHIMOTO, Jiro

Inventor： SHISEIDO COMPANY LTD.

IPC: C12N01/20

CPC classification number: C12P17/186 ,  C07K14/585 ,  C12N15/52 ,  C12R1/19 ,  C21B13/002 ,  Y02P10/136

Abstract: Escherichia coli characterized in that a capability thereof of forming acetate is at most one fifth that of wild type Escherichia coli, and a process for producing a useful substance by cultivating the Escherichia coli to a high density and recovering the substance.

公开(公告)号：WO1988005453A1

公开(公告)日：1988-07-28

申请号：PCT/JP1988000059

申请日：1988-01-26

Applicant: SHISEIDO COMPANY LTD. ,  TOPY KOGYO KABUSHIKI KAISHA ,  OHNO, Kazuhisa ,  KOSUGI, Tetsushi ,  SUGIMORI, Kenichiro ,  ANDO, Akitusgu ,  YAMAMOTO, Masaru ,  SUZUKI, Fukuji ,  NAKAMURA, Masahiro ,  TSUJITA, Nobuhisa

Inventor： SHISEIDO COMPANY LTD. ,  TOPY KOGYO KABUSHIKI KAISHA

IPC: C09C01/28

CPC classification number: A61K8/26 ,  A61K2800/43 ,  A61Q1/02 ,  A61Q1/08 ,  A61Q1/12 ,  A61Q3/02 ,  B82Y30/00 ,  C01B33/28 ,  C01B33/425 ,  C01P2002/72 ,  C01P2004/03 ,  C01P2004/20 ,  C01P2004/61 ,  C01P2004/64 ,  C01P2006/12 ,  C01P2006/60 ,  C01P2006/65 ,  C01P2006/80 ,  C09C1/28 ,  Y10T428/2982

Abstract: A synthetic mica powder containing 75 to 99 % of fluorine based on the stoichiometric composition and/or having thin leaf-like particle edges, a process for its production, and cosmetics containing said powder. This powder does not release fluoride ion and/or the thin leaf-like particle surface can contain an oily substance in a sufficient amount to provide cosmetics having excellent spreadability, luster, adhesiveness, and moldability, giving an appearance with high saturation, and having high stability and safety.

公开(公告)号：WO2022130140A1

公开(公告)日：2022-06-23

申请号：PCT/IB2021/061538

申请日：2021-12-09

Applicant: SHISEIDO COMPANY, LTD.

Inventor： TAJIMA, Shoji

IPC: A61K8/26 ,  A61K8/29 ,  A61K8/25 ,  A61Q1/12

Abstract: Provided is a cosmetic composition that includes at least one micaceous pigment and at least one pearlescent pigment.