公开(公告)号：KR1020160142713A

公开(公告)日：2016-12-13

申请号：KR1020150078800

申请日：2015-06-03

Applicant: 대구한의대학교산학협력단

Inventor： 김상찬 ,  최홍식 ,  손호영 ,  조일제 ,  박상미 ,  정지윤 ,  구세광

IPC: A61K36/282 ,  A23L1/30

Abstract: 본발명은청호추출물을유효성분으로함유하는간질환의예방또는치료용조성물에관한것으로, 본발명의청호추출물은 AMPK pathway 활성화및 미토콘드리아보호작용을통한간세포보호효과가우수하고, 간보호작용을보이며정상세포에독성을유발하지않는다는것을확인함으로써, 간질환치료제또는간질환예방을위한건강기능성식품의유효성분으로사용할수 있다.

公开(公告)号：KR101146861B1

公开(公告)日：2012-05-16

申请号：KR1020100000817

申请日：2010-01-06

Applicant: 대구한의대학교산학협력단

Inventor： 김상찬 ,  최홍식 ,  박숙자 ,  이종록 ,  박원묵 ,  박상미 ,  조미정

IPC: A61K36/48 ,  A61P1/16 ,  A61P1/00

Abstract: PURPOSE: A composition containing Statholobi Caulis extract is provided to reduce H4IIE cytotoxicity induced by cadmium and to protect liver. CONSTITUTION: A pharmaceutical composition for preventing and treating liver disease contains Statholobi Caulis extract as an active ingredient. The Statholobi Caulis extract is a soluble in water including purified water, low alcohol of C1-C4, or mixture solvent thereof. A health food for preventing and treating alcoholic liver diseases contains Statholobi Caulis extract as an active ingredient. The health food is used in the form of powder, granule, tablet, capsule, or beverage.

公开(公告)号：KR1020110080543A

公开(公告)日：2011-07-13

申请号：KR1020100000817

申请日：2010-01-06

Applicant: 대구한의대학교산학협력단

Inventor： 김상찬 ,  최홍식 ,  박숙자 ,  이종록 ,  박원묵 ,  박상미 ,  조미정

IPC: A61K36/48 ,  A61P1/16 ,  A61P1/00

CPC classification number: A61K36/48 ,  A61K2236/331 ,  A61K2236/333 ,  Y10S514/894

Abstract: PURPOSE: A composition containing Statholobi Caulis extract is provided to reduce H4IIE cytotoxicity induced by cadmium and to protect liver. CONSTITUTION: A pharmaceutical composition for preventing and treating liver disease contains Statholobi Caulis extract as an active ingredient. The Statholobi Caulis extract is a soluble in water including purified water, low alcohol of C1-C4, or mixture solvent thereof. A health food for preventing and treating alcoholic liver diseases contains Statholobi Caulis extract as an active ingredient. The health food is used in the form of powder, granule, tablet, capsule, or beverage.

Abstract translation: 目的：提供含有斑马鱼提取物的组合物，以减少镉引起的H4IIE细胞毒性并保护肝脏。 构成：用于预防和治疗肝病的药物组合物含有斑马鱼提取物作为活性成分。 斑马提取物是可溶于水，包括纯水，C1-C4的低级醇或其混合溶剂。 一种用于预防和治疗酒精性肝病的保健食品含有斑马鱼提取物作为活性成分。 保健食品以粉末，颗粒，片剂，胶囊或饮料的形式使用。