公开(公告)号：KR101821350B1

公开(公告)日：2018-01-25

申请号：KR1020110076013

申请日：2011-07-29

Applicant: 에스케이텔레콤 주식회사 ,  서울대학교산학협력단

Inventor： 김영두 ,  최성현 ,  최문환 ,  신연철 ,  구종회 ,  손위평

IPC: H04L1/00 ,  H04L12/70 ,  H03M13/03

Abstract: 본발명에서는무선랜기반의멀티-셀멀티캐스트환경에서의비디오전송에있어서, 단말장치로멀티캐스트비디오패킷을전송하여주는각각의액세스포인트등의무선통신장치가단말장치와의무선채널정보를바탕으로멀티캐스트비디오패킷의전송을위한 FEC 인코딩비율을독립적으로설정하여멀티캐스트비디오패킷의전송효율을높이도록한다. 즉, 비디오멀티캐스트서비스를받는단말장치들이무선채널정보를 FEC 인코딩비율조정기능을구비하는액세스포인트등의무선통신장치로피드백하고, 무선채널정보를이용하여액세스포인트별독립적인 FEC 인코딩비율을사용하도록함으로써낮은 FEC 인코딩비율로인한무선자원의불필요한낭비를방지시킬수 있다. 또한, 동일채널에서동작하는액세스포인트들이서로겹치는전송영역을가지고있는경우액세스포인트들간비디오패킷의전송시기를서로다르게설정하여겹치는전송영역에위치한단말장치에서비디오패킷의충돌이발생하지않도록한다.

公开(公告)号：KR101213325B1

公开(公告)日：2012-12-18

申请号：KR1020100014876

申请日：2010-02-18

Applicant: 서울대학교산학협력단

Inventor： 정용근 ,  최현우 ,  김영두

IPC: C12N15/85 ,  C12N15/12 ,  A01K67/027

Abstract: 본발명은델타-tau 유전자를발현하는형질전환알츠하이머형치매동물및 이의제조방법에관한것이다. 본발명에따른 &Dgr;tau 유전자를발현하는형질전환알츠하이머형치매동물은, BAI1-AP4 프로모터와, tau 단백질의 C-말단부위에서 421번아미노산(아스파르트산, Asp421)과 422번아미노산사이부분이절단되어 1번~421번의아미노산영역을코딩하는인간 &Dgr;tau 유전자를연결시켜형질전환용벡터를구축하고, 상기벡터를동물의수정란에주입한다음, 상기수정란을대리모동물에착상시켜생산되는것을특징으로한다.

公开(公告)号：KR1020130014093A

公开(公告)日：2013-02-07

申请号：KR1020110076013

申请日：2011-07-29

Applicant: 에스케이텔레콤 주식회사 ,  서울대학교산학협력단

Inventor： 김영두 ,  최성현 ,  최문환 ,  신연철 ,  구종회 ,  손위평

IPC: H04L1/00 ,  H04L12/56 ,  H03M13/03

CPC classification number: H04N21/6405 ,  H04L1/0041 ,  H04W84/12

Abstract: PURPOSE: In a wireless LAN environment, a video transmission system, a wireless communication apparatus and a method thereof are provided to use wireless channel information, thereby use independent FEC(Forward Error Correction) encoding rate per access point. CONSTITUTION: A video server(400) stores various video contents for a multimedia internet service. The video server provides the stored various video contents to terminal devices(408,410,412,414) through communications network. The video server divides video data into packets before delivering the video data to access points(402,404,406). The video server encodes the divided packet form video data by using a predetermined packet level FEC coding method. The video server transmits the encoded video data to the terminal devices through each access point. [Reference numerals] (400) Video server; (402,404,406) Access point; (AA) Application layer FEC encoding; (BB) FEC rate control through parity packet deletion; (CC) Application layer FEC decoding; (DD) Resource-saving effect; (EE) Wireless channel loss

Abstract translation: 目的：在无线LAN环境中，提供视频传输系统，无线通信装置及其方法以使用无线信道信息，从而对每个接入点使用独立的FEC（前向纠错）编码率。 规定：视频服务器（400）存储用于多媒体互联网服务的各种视频内容。 视频服务器通过通信网络将存储的各种视频内容提供给终端设备（408,410,412,414）。 视频服务器在将视频数据传送到接入点之前将视频数据分割成包（402,404,406）。 视频服务器通过使用预定的分组级FEC编码方法来对分割的分组格式的视频数据进行编码。 视频服务器通过每个接入点将编码的视频数据发送到终端设备。 （附图标记）（400）视频服务器; （402,404,406）接入点; （AA）应用层FEC编码; （BB）通过奇偶校验分组删除进行FEC速率控制; （CC）应用层FEC解码; （DD）资源节约效应; （EE）无线信道丢失

公开(公告)号：KR1020140103603A

公开(公告)日：2014-08-27

申请号：KR1020130017181

申请日：2013-02-18

Applicant: 서울대학교산학협력단

Inventor： 정용근 ,  김영두 ,  쥬닝유안

IPC: A61K31/445 ,  A61P25/28 ,  A61P25/00

CPC classification number: A61K31/454

Abstract: The present invention relates to a medicine for treating neurodegenerative disease and, more specifically, to a composition for preventing and treating tau protein-mediated neurodegenerative disease, comprising pimozide as an active ingredient, whereby neurodegenerative disease is caused by phosphorylation and aggregation of tau proteins.

Abstract translation: 本发明涉及一种治疗神经变性疾病的药物，更具体地说，涉及一种用于预防和治疗tau蛋白介导的神经变性疾病的组合物，其包含作为活性成分的匹莫齐地，其中由tau蛋白的磷酸化和聚集引起神经变性疾病。

公开(公告)号：KR1020110095067A

公开(公告)日：2011-08-24

申请号：KR1020100014876

申请日：2010-02-18

Applicant: 서울대학교산학협력단

Inventor： 정용근 ,  최현우 ,  김영두

IPC: C12N15/85 ,  C12N15/12 ,  A01K67/027

Abstract: PURPOSE: A method for preparing a transgenic dementia animal of Alzheimer type is provided to express human delta-tau protein in cerebral cortex, hippocampus, and bovine brain and to enhance hyperphosphorylation and agglomeration of tau protein. CONSTITUTION: A vector for transformation contains BAI1-AP4 promoter and human delt-tau gene encoding 1-421th amino acid region cutting between 421th(aspartic acid, Asp421) and 422th amino acids in tau protein C-terminal. BAI1-AP4 promoter is a promoter which specifically expresses in cerebral cortex and Hippocampus region of a mouse. A transgenic dementia animal(deposit number: KCTC11622BP) of Alzheimer type is prepared by introducing the vector. A method for preparing the animal comprises: a step of constructing the vector; a step of injecting the vector to a fertilized egg; and a step of performing implantation of the fertilized egg to an animal.

Abstract translation: 目的：提供一种制备阿尔茨海默型转基因痴呆动物的方法，以在大脑皮质，海马和牛脑中表达人类δ-tau蛋白，并增强tau蛋白的过度磷酸化和凝聚。 构成：转化载体含有编码1-4位氨基酸区域的BAI1-AP4启动子和人类delt-tau基因，其在第421位（天冬氨酸，Asp421）和tau蛋白C末端的第422位氨基酸之间切割。 BAI1-AP4启动子是在小鼠的大脑皮质和海马区特异性表达的启动子。 通过引入载体制备阿尔茨海默型的转基因痴呆动物（保藏号：KCTC11622BP）。 制备动物的方法包括：构建载体的步骤; 将载体注射到受精卵的步骤; 以及将受精卵植入动物的步骤。