公开(公告)号：WO1994004502A1

公开(公告)日：1994-03-03

申请号：PCT/US1993007521

申请日：1993-08-11

Applicant: ABBOTT LABORATORIES

Inventor： ABBOTT LABORATORIES ,  WANG, Xiu, C. ,  KALARITIS, Panos ,  CHANG, Michelle, L.

IPC: C07D213/90

CPC classification number: C07D213/20 ,  C07C51/377 ,  C07C201/12 ,  C07C63/70 ,  C07C205/58

Abstract: A process for the preparation of halobenzoic acids, comprising the step of reacting a halonitrobenzene with a pyridinium salt to form an intermediate of formula (I), wherein R is selected from the group consisting of hydrogen, alkyl, aryl, alkenyl, alkynyl, -CN, -COOR' and -COR' where R' is alkyl or aryl; X is chloro or fluoro; Y is hydrogen, chloro or fluoro; and Z is chloro, bromo or iodo.

Abstract translation: 一种制备卤代苯甲酸的方法，包括使卤代硝基苯与吡啶鎓盐反应形成式（I）的中间体的步骤，其中R选自氢，烷基，芳基，烯基，炔基， CN，-COOR'和-COR'，其中R'是烷基或芳基; X是氯或氟; Y是氢，氯或氟; Z是氯，溴或碘。

公开(公告)号：EP0655997B1

公开(公告)日：1997-02-12

申请号：EP93919956.8

申请日：1993-08-11

Applicant: ABBOTT LABORATORIES

Inventor： WANG, Xiu, C. ,  KALARITIS, Panos ,  CHANG, Michelle, L.

IPC: C07D213/20 ,  C07C205/58

CPC classification number: C07D213/20 ,  C07C51/377 ,  C07C201/12 ,  C07C63/70 ,  C07C205/58

Abstract: A process for the preparation of halobenzoic acids, comprising the step of reacting a halonitrobenzene with a pyridinium salt to form an intermediate of formula (I), wherein R is selected from the group consisting of hydrogen, alkyl, aryl, alkenyl, alkynyl, -CN, -COOR' and -COR' where R' is alkyl or aryl; X is chloro or fluoro; Y is hydrogen, chloro or fluoro; and Z is chloro, bromo or iodo.

公开(公告)号：EP0655997A1

公开(公告)日：1995-06-07

申请号：EP93919956.0

申请日：1993-08-11

Applicant: ABBOTT LABORATORIES

Inventor： WANG, Xiu, C. ,  KALARITIS, Panos ,  CHANG, Michelle, L.

IPC: C07C51 ,  C07C63 ,  C07C205 ,  C07D213

CPC classification number: C07D213/20 ,  C07C51/377 ,  C07C201/12 ,  C07C63/70 ,  C07C205/58

Abstract: A process for the preparation of halobenzoic acids, comprising the step of reacting a halonitrobenzene with a pyridinium salt to form an intermediate of formula (I), wherein R is selected from the group consisting of hydrogen, alkyl, aryl, alkenyl, alkynyl, -CN, -COOR' and -COR' where R' is alkyl or aryl; X is chloro or fluoro; Y is hydrogen, chloro or fluoro; and Z is chloro, bromo or iodo.