公开(公告)号：JP2002058388A

公开(公告)日：2002-02-26

申请号：JP2000246570

申请日：2000-08-15

Applicant: ACADEMIA SINICA

Inventor： LEE IN-FE

IPC: A01K67/027 ,  C12N5/10 ,  C12N15/09 ,  C12R1/91

Abstract: PROBLEM TO BE SOLVED: To obtain a transgenic animal model for providing better knowledge about a phenomenon of molecules for adjusting the differentiation of fat cells and the storage of fat at an organic level in order to more understand a mechanism for leading to obesity and develop a strategy for controlling a specific type of obesity. SOLUTION: This transgenic animal in which the genomic DNA comprises a gene containing a C/EBPα promoter operably linked to a DNA sequence encoding a C/EBPβ polypetide. In the transgenic animal, the genomic DNA is capable of exhibiting fat accumulation reduced in white fat tissues of the transgenic animal as compared with a control animal without containing the gene.