公开(公告)号：US3862958A

公开(公告)日：1975-01-28

申请号：US30424172

申请日：1972-11-06

Applicant: BASF AG

Inventor： RUECHARDT CHRISTOPH ,  HASSMANN VOLKER ,  QUADBECK-SEEGER HANS-JUERGEN ,  ARMBRUST HERBERT

IPC: C07D231/56 ,  C07D249/10

CPC classification number: C07D249/10 ,  C07D231/56

Abstract: Preparation of indazoles by reacting o-toluidines with alkyl nitrites, esters of glycols or glycol derivatives with nitrous acid, and/or nitrous gases in the presence of acetic anhydride, an alkali metal salt of an alkanoic acid and an organic solvent followed by elimination of the acetyl group from the 1acetylindazole formed. The compounds prepared by the process of the invention are valuable intermediates in the manufacture of dyes, pharmaceuticals and pesticides.

Abstract translation: 在乙酸酐，链烷酸的碱金属盐和有机溶剂的存在下，使邻甲苯胺与亚硝酸烷基酯，二醇或二醇衍生物与亚硝酸的酯和/或亚硝基气体反应制备吲唑，然后除去 形成来自1-乙酰基吲唑基的乙酰基。 通过本发明方法制备的化合物是制造染料，药物和农药的有价值的中间体。