公开(公告)号：WO2019121053A1

公开(公告)日：2019-06-27

申请号：PCT/EP2018/083906

申请日：2018-12-07

Applicant: BASF SE

Inventor： GUTH, Felicitas ,  KOLTER, Karl ,  LANGLEY, Nigel ,  FREIDL, Kerri ,  BRUEGGEMANN, Kristina

IPC: C12N5/00

CPC classification number: C12N5/0018 ,  C12N5/00 ,  C12N2500/50

Abstract: A method for stabilizing cells in cell culture production, the method comprising culturing a cell line capable of expressing proteins in cell culture media, and supplementing said cell culture media with a graft polymer in which N-vinyl caprolactam and vinyl acetate moieties are grafted on a polyethylene glycol backbone.