公开(公告)号：JP2013155183A

公开(公告)日：2013-08-15

申请号：JP2013078582

申请日：2013-04-04

Applicant: Basf Se ,  ビーエーエスエフ ソシエタス・ヨーロピアBasf Se

Inventor： BERGNER EIKE JOHANNES ,  EBEL KLAUS ,  THORSTEN JOHANN ,  OLIVER LOEBER

IPC: C07C29/17 ,  A23L27/20 ,  B01J27/232 ,  B01J31/24 ,  C07B53/00 ,  C07B61/00 ,  C07C29/56 ,  C07C29/76 ,  C07C33/025 ,  C07C35/12 ,  C07C35/17 ,  C07C45/29 ,  C07C47/21

CPC classification number: C07C29/17 ,  C07B2200/07 ,  C07C29/172 ,  C07C45/002 ,  C07C2601/14 ,  C12C11/02 ,  C07C33/025 ,  C07C35/12 ,  C07C29/56 ,  C07C35/17 ,  C07C47/21

Abstract: PROBLEM TO BE SOLVED: To provide a method of asymmetrically synthesizing optical activity menthol from one or more inexpensive achiral starting materials that do not require isolation from a natural supply source.SOLUTION: (a) Optical activity citronellol is obtained by enantio-selectively hydrogenating geraniol, nerol, or a mixture of geraniol and nerol, (b) optical activity citronellal is obtained by reaction of the obtained optical activity citronellol, (c) a mixture containing optical activity isopulegol is obtained by cyclizing the obtained optical activity citronellal, and (d) optical activity menthol is obtained by extracting the optical activity isopulegol from the obtained mixture and then hydrogenating it, or by hydrogenating the optical activity isopulegol contained in the mixture to produce optical activity menthol and then extracting the obtained optical activity menthol from the mixture obtained as a hydrogenated product. Thus, in this method, optical activity menthol is manufactured from geraniol, nerol, or a mixture of geraniol and nerol.

Abstract translation: 要解决的问题：提供从不需要与天然供应源分离的一种或多种廉价的非手性起始原料不对称地合成光学活性薄荷醇的方法。解决方案：（a）通过对映选择性氢化香叶醇获得光学活性香茅醇 ，橙花醇或香叶醇和橙花醇的混合物，（b）通过所得光学活性香茅醇反应获得光学活性香茅醛，（c）通过使获得的光学活性香茅醛环化获得含有光学活性的混合物， ）光学活性薄荷醇通过从获得的混合物中提取光学活性异双胍，然后将其氢化，或通过氢化混合物中所含的光学活性异双胍获得光学活性薄荷醇，然后从获得的混合物中提取所得的光学活性薄荷醇 氢化产物。 因此，在该方法中，光学活性薄荷脑由香叶醇，橙花醇或香叶醇和橙花醇的混合物制成。

公开(公告)号：MY145446A

公开(公告)日：2012-02-15

申请号：MYPI20090102

申请日：2007-07-09

Applicant: BASF SE

Inventor： THORSTEN JOHANN ,  HEIKO URTEL ,  YIN CHIN SOO

IPC: C07C45/00

Abstract: A METHOD FOR DEHYDROGENATING PRIMARY OR SECONDARY ALCOHOLS HAVING 1 TO 12 CARBON ATOMS TO GIVE THE CORRESPONDING ALDEHYDES OR KETONES IN WHICH THE ALCOHOL IS BROUGHT INTO CONTACT WITH A CATALYTICALLY ACTIVE COMPOSITION COMPRISING AN ACTIVE COMPONENT OF THE FORMULA PDABIBYCZD, WHERE Y IS SELECTED FROM THE GROUP CONSISTING OF CO, RH, PT, AG, AU, AND ( Z IS SELECTED FROM THE GROUP CONSISTING OF NA, CS, MG, CA, BA, V, CR, W, FE, NI, CU, SB WHERE THE INDICES A, B, C AND D GIVE THE MASS RATIOS OF THE RESPECTIVE ELEMENTS TO ONE ANOTHER, WHERE A= 0.1 - 3, B = 0.1 - 3, 15 C = 0 - 3, D = 0 - 1.

公开(公告)号：MY145433A

公开(公告)日：2012-02-15

申请号：MYPI20084963

申请日：2008-12-05

Applicant: BASF SE

Inventor： STEFFEN MAAS ,  THORSTEN JOHANN ,  MICHAEL KOCH ,  TILMAN SIRCH ,  STEPHAN SCHLITTER ,  STEFAN RITTINGER ,  MICHAEL STEINIGER ,  SPENGEMAN TODD C

IPC: C07C27/04

Abstract: PROCESS FOR HYDROGENATING METHYLOLALKANALS 5 R 1 OHCH2--C-CHO 1 2 R 10 A PROCESS FOR CATALYTICALLY HYDROGENATING METHYLOLALKANALS OF THE GENERAL FORMULA (1) IN WHICH R1 AND R2 EACH SIGNIFIES, INDEPENDENT OF ONE ANOTHER, A FURTHER METHYLOL GROUP OR AN ALKYL GROUP HAVING FROM I TO 22 C ATOMS, OR AN ARYL OR ARALKYL GROUP HAVING FROM 6 TO 33 C ATOMS, IN THE LIQUID PHASE WITH HYDROGEN OVER A HYDROGENATION CATALYST, CHARACTERIZED BY THE USE OF THE MOLAR RATIO OF 1 5 HYDROGEN TO METHYLOLALKANAL OF GREATER THAN 1.