公开(公告)号：AU2003282634A1

公开(公告)日：2004-02-25

申请号：AU2003282634

申请日：2003-03-20

Applicant: CALIFORNIA INST OF TECHN

Inventor： DAM MICHAEL VAN ,  UNGER MARC A ,  QUAKE STEPHEN R

IPC: B01J19/00 ,  B81B1/00 ,  C07B61/00 ,  C12Q20060101 ,  C40B40/06 ,  C40B40/10 ,  C40B50/14 ,  C40B60/14 ,  G01N1/00 ,  G01N15/06 ,  G01N21/00 ,  G01N21/29 ,  G01N27/00 ,  G01N27/12 ,  G01N33/00 ,  G01N33/48

Abstract: The present invention provides a microfluidic device for synthesizing an array of compounds and methods for using the same. In particular, the microfluidic device of the present invention comprises a solid support base, an elastomeric layer attached to the solid support, and a plurality of flow channels located within the interface between the solid support and the elastomeric layer. In addition, the solid support comprises a functional group for forming a bond with a reactive reagent. In some embodiments, the microfluidic device further comprises a second plurality of flow channels that intersect the first plurality of flow channels. A plurality of control channels are also present in the microfluidic devices of the present invention. The control channels can be actuated to regulate flow of fluids within the flow channel(s).

公开(公告)号：AU2003282634A8

公开(公告)日：2004-02-25

申请号：AU2003282634

申请日：2003-03-20

Applicant: CALIFORNIA INST OF TECHN

Inventor： DAM MICHAEL VAN ,  UNGER MARC A ,  QUAKE STEPHEN R

IPC: B01J19/00 ,  B81B1/00 ,  C07B61/00 ,  C12Q20060101 ,  C40B40/06 ,  C40B40/10 ,  C40B50/14 ,  C40B60/14 ,  G01N1/00 ,  G01N15/06 ,  G01N21/00 ,  G01N21/29 ,  G01N27/00 ,  G01N27/12 ,  G01N33/00 ,  G01N33/48

Abstract: The present invention provides a microfluidic device for synthesizing an array of compounds and methods for using the same. In particular, the microfluidic device of the present invention comprises a solid support base, an elastomeric layer attached to the solid support, and a plurality of flow channels located within the interface between the solid support and the elastomeric layer. In addition, the solid support comprises a functional group for forming a bond with a reactive reagent. In some embodiments, the microfluidic device further comprises a second plurality of flow channels that intersect the first plurality of flow channels. A plurality of control channels are also present in the microfluidic devices of the present invention. The control channels can be actuated to regulate flow of fluids within the flow channel(s).

公开(公告)号：HK1106262A1

公开(公告)日：2008-03-07

申请号：HK08100301

申请日：2008-01-09

Applicant: UNIV NORTH CAROLINA ,  CALIFORNIA INST OF TECHN

Inventor： JOSEPH M DESIMONE M ,  JASON P ROLLAND P ,  STEPHEN R QUAKE R ,  DEREK A SCHORZMAN A ,  YARBROUGH JASON ,  DAM MICHAEL VAN

IPC: B05D20060101 ,  B81B1/00 ,  C08G20060101 ,  C08J20060101 ,  H01M20060101

公开(公告)号：AU2004276302A1

公开(公告)日：2005-04-07

申请号：AU2004276302

申请日：2004-09-23

Applicant: UNIV NORTH CAROLINA ,  CALIFORNIA INST OF TECHN

Inventor： SCHORZMAN DEREK A ,  DAM MICHAEL VAN ,  ROLLAND JASON P ,  QUAKE STEPHEN R ,  DESIMONE JOSEPH M ,  YARBROUGH JASON

IPC: C08G85/00 ,  B81B1/00 ,  C08G20060101