公开(公告)号：ES2283002T3

公开(公告)日：2007-10-16

申请号：ES96916256

申请日：1996-06-07

Applicant: HOWARD FOUNDATION

Inventor： HOWARD ALAN NORMAN ,  LANDRUM JOHN THOMAS ,  BONE RICHARD ANDREW

IPC: A61K31/045 ,  A23L33/00 ,  A23L33/15 ,  A23L33/155 ,  A61K31/047 ,  A61K31/07 ,  A61K31/12 ,  A61K31/22 ,  A61K31/23 ,  A61K31/355 ,  A61K31/375 ,  A61K33/04 ,  A61K33/24 ,  A61K33/34 ,  A61P27/00

Abstract: SE DESCRIBEN LOS CAROTENOIDES LUTEINA Y ZEAXANTINA PARA SU USO FARMACEUTICO EN EL TRATAMIENTO DE LA DEGENERACION MACULAR AVANZADA. SE DESPLIEGAN ELEVADAS CONCENTRACIONES PARA PRODUCIR LOS NIVELES ELEVADOS DE CAROTENOIDES EN SUERO QUE SE NECESITAN PARA QUE SEAN CAPTADOS POR LA MACULA.

公开(公告)号：CA2284120C

公开(公告)日：2006-11-14

申请号：CA2284120

申请日：1998-03-04

Applicant: HOWARD FOUNDATION

Inventor： ORTA CARLOS MANUEL ,  HUANG WENLUE ,  LANDRUM JOHN THOMAS ,  BONE RICHARD ANDREW

IPC: G01J1/34 ,  A61B3/06 ,  A61B3/10 ,  A61B3/14 ,  G01J1/22

Abstract: A flicker photometer has beam generating means (1, 8 and 4) for generating two beams of light of different colours. Light from the beams is viewed at the viewing means, and the intensity of light of one beam relative to that of the other beam can be adjusted by adjustment means comprising an attenuating filter (20) which is movably mounted in the path of one beam. Movement of the filter relative to the beam alters the degree to which the beam is attenuated, and is achieved using an electric motor (22). The motor provides a relatively easy means of adjusting the filter position, and can be used to provide coarse and fine adjustments in response to suitable signals from an optical encoder. The motor also enables the filter, along with the beam generating means, to be mounted on a movable table for use in enabling the photometer to accommodate both short and long-sighted subjects.

公开(公告)号：ZA982011B

公开(公告)日：1999-09-10

申请号：ZA982011

申请日：1998-03-10

Applicant: HOWARD FOUNDATION

Inventor： BONE RICHARD ANDREW ,  LANDRUM JOHN THOMAS ,  HUANG WENLUE ,  ORTA CARLOS MANUEL

IPC: A61B3/02 ,  A61B3/06 ,  G01J3/08 ,  A61B ,  G01J

Abstract: A flicker photometer comprises generating means (1, 8, 4) for generating two beams of light of different colours. Both beams are directed to a viewing means (190), and a subject can vary the intensity of light from one beam relative to the other. The colour of the light seen by the subject is caused to alternate. The performance of the photometer is improved by screens which scatter light before it reaches the subject. A first of the screens (186, 188) reflects light from one beam, whilst a second screen (b) is translucent, and thus transmits light from the other. If light of wavelengths to which the eye is less sensitive is passed through the second screen, whilst light of a wavelength to which the eye is more sensitive passes through the first screen, the screens help to make it practicable for the generating means to use a single lamp (1) to produce the light for both beams.

公开(公告)号：CA2284120A1

公开(公告)日：1998-09-17

申请号：CA2284120

申请日：1998-03-04

Applicant: HOWARD FOUNDATION

Inventor： BONE RICHARD ANDREW ,  ORTA CARLOS MANUEL ,  HUANG WENLUE ,  LANDRUM JOHN THOMAS

IPC: A61B3/06 ,  G01J1/22 ,  G01J1/34

Abstract: A flicker photometer has beam generating means (1, 8 and 4) for generating two beams of light of different colours. Light from the beams is viewed at the viewing means, and the intensity of light of one beam relative to that of the other beam can be adjusted by adjustment means comprising an attenuating filter (20) which is movably mounted in the path of one beam. Movement of the filter relative to the beam alters the degree to which the beam is attenuated, and is achieved using an electric motor (22). The motor provides a relatively easy means of adjusting the filter position, and can be used to provide coarse and fine adjustments in response to suitable signals from an optical encoder. The motor also enables the filter, along with the beam generating means, to be mounted on a movable table for use in enabling the photometer to accommodate both short and long-sighted subjects.

公开(公告)号：GB2323162B

公开(公告)日：2001-08-15

申请号：GB9804445

申请日：1998-03-04

Applicant: HOWARD FOUNDATION

Inventor： BONE RICHARD ANDREW ,  LANDRUM JOHN THOMAS ,  HUANG WENLUE ,  ORTA CARLOS MANUEL

IPC: A61B3/06 ,  G01J1/22 ,  G01J1/34 ,  A61B3/02

Abstract: A flicker photometer has beam generating means (1, 8 and 4) for generating two beams of light of different colors. Light from the beams is viewed at the viewing means, and the intensity of light of one beam relative to that of the other beam can be adjusted by adjustment means comprising an attenuating filter (20) which is movably mounted in the path of one beam. Movement of the filter relative to the beam alters the degree to which the beam is attenuated, and is achieved using an electric motor (22). The motor provides a relatively easy means of adjusting the filter position, and can be used to provide coarse and fine adjustments in response to suitable signals from an optical encoder. The motor also enables the filter, along with the beam generating means, to be mounted on a movable table for use in enabling the photometer to accommodate both short and long-sighted subjects.

公开(公告)号：ZA9802014B

公开(公告)日：1999-09-10

申请号：ZA9802014

申请日：1998-03-10

Applicant: HOWARD FOUNDATION

Inventor： BONE RICHARD ANDREW ,  LANDRUM JOHN THOMAS ,  HUANG WENLUE ,  ORTA CARLOS MANUEL

IPC: A61B3/06 ,  G01J1/22 ,  G01J1/34 ,  G01J

CPC classification number: A61B3/063 ,  G01J1/22 ,  G01J1/34

公开(公告)号：ZA9802011B

公开(公告)日：1999-09-10

申请号：ZA9802011

申请日：1998-03-10

Applicant: HOWARD FOUNDATION

Inventor： BONE RICHARD ANDREW ,  LANDRUM JOHN THOMAS ,  HUANG WENLUE ,  ORTA CARLOS MANUEL

IPC: A61B3/02 ,  A61B3/06 ,  G01J3/08 ,  A61B ,  G01J

CPC classification number: A61B3/02

公开(公告)号：GB2356701A

公开(公告)日：2001-05-30

申请号：GB0105344

申请日：1998-03-04

Applicant: HOWARD FOUNDATION

Inventor： BONE RICHARD ANDREW ,  LANDRUM JOHN THOMAS ,  HUANG WENLUE ,  ORTA CARLOS MANUEL

IPC: A61B3/02 ,  A61B3/12

公开(公告)号：GB2301775B

公开(公告)日：1999-08-04

申请号：GB9611967

申请日：1996-06-07

Applicant: HOWARD FOUNDATION

Inventor： HOWARD ALAN NORMAN ,  BONE RICHARD ANDREW ,  LANDRUM JOHN THOMAS

IPC: A23L33/00 ,  A23L33/15 ,  A23L33/155 ,  A61K31/045 ,  A61K31/047 ,  A61K31/07 ,  A61K31/12 ,  A61K31/22 ,  A61K31/23 ,  A61K31/355 ,  A61K31/375 ,  A61K33/04 ,  A61K33/24 ,  A61K33/34

Abstract: The carotenoids lutein and zeaxanthin are used either separately or in combination to treat age-related macular degeneration (AMD). The carotenoids are administered in the form of a pharmaceutical preparation, e.g. a capsule or alternatively as a food e.g. a genetically engineered tomato producing enhanced levels of carotenoid. High dosages of lutein and zeaxanthin are needed to ensure high serum levels necessary for take up of the carotenoids by the macula.

公开(公告)号：AU6507598A

公开(公告)日：1998-09-29

申请号：AU6507598

申请日：1998-03-04

Applicant: HOWARD FOUNDATION

Inventor： BONE RICHARD ANDREW ,  LANDRUM JOHN THOMAS ,  HUANG WENLUE ,  ORTA CARLOS MANUEL

IPC: A61B3/06 ,  G01J1/22 ,  G01J1/34

Abstract: A flicker photometer has beam generating means (1, 8 and 4) for generating two beams of light of different colors. Light from the beams is viewed at the viewing means, and the intensity of light of one beam relative to that of the other beam can be adjusted by adjustment means comprising an attenuating filter (20) which is movably mounted in the path of one beam. Movement of the filter relative to the beam alters the degree to which the beam is attenuated, and is achieved using an electric motor (22). The motor provides a relatively easy means of adjusting the filter position, and can be used to provide coarse and fine adjustments in response to suitable signals from an optical encoder. The motor also enables the filter, along with the beam generating means, to be mounted on a movable table for use in enabling the photometer to accommodate both short and long-sighted subjects.