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公开(公告)号：WO2017143194A8
公开(公告)日：2017-08-24
申请号：PCT/US2017/018375
申请日：2017-02-17
Inventor： SMITH, Gary , CONRADIE, Alex, Van Eck , KIRBY, Gregory, S. , PEARLMAN, Paul, S.
Abstract: Biocatalytic processes for producing a product wherein an aqueous stream comprising at least one fermentable substrate and/or a gaseous stream comprising at least one of CO 2 /H 2 , H 2 , methane, and/or CO are povided to a fermentation zone comprising at least one organism capable of metabolizing a substance present in one of the streams. The fermentation may operate at conditions to mixotrophically metabolize at least one gaseous substrate and at least one substrate present in the aqueous stream.
Abstract translation: 用于生产产物的生物催化方法，其中包含至少一种可发酵底物的含水物流和/或包含CO 2 / H 2中的至少一种的气态物流 甲烷和/或CO被提供给包含至少一种能够代谢存在于其中一种物质中的物质的生物体的发酵区。 发酵可以在混合营养代谢至少一种气态底物和存在于含水流中的至少一种底物的条件下进行。
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公开(公告)号：WO2017143194A2
公开(公告)日：2017-08-24
申请号：PCT/US2017/018375
申请日：2017-02-17
Inventor： SMITH, Gary , CONRADIE, Alex, Van Eck , KIRBY, Gregory, S. , PEARLMAN, Paul, S.
CPC classification number: C12P13/001 , C12M29/00 , C12M41/00 , C12N1/20 , C12P5/00 , C12P5/007 , C12P5/02 , C12P7/065 , C12P7/24 , C12P7/625 , C12P13/00 , C25B1/04 , F01D15/10 , F01K7/16 , F01K11/02 , F05D2220/31 , Y02E50/343 , Y02E60/366
Abstract: The present disclosure describes biocatalytic processes for producing a product, comprising providing an aqueous stream (AS) comprising at least one fermentable substrate and a gaseous stream (GS) comprising at least one of CO 2 /H 2 , H 2 , methane, and/or CO to a fermentation zone, wherein the GS and AS stream are optionally contacted and/or mixed; the fermentation zone comprising at least one organism capable of metabolizing an AS substrate and a GS substrate, wherein the fermentation operates at conditions to mixotrophically metabolize at least one gaseous substrate in the GS and at least one substrate in the AS, producing the product. The present disclosure also describes compositions comprising an AS, a GS, and an organism, wherein the organism or an equivalent or engineered equivalent thereof is a methanotroph or a hydrogen-metabolizing or CO-metabolizing chemolithotrophic organism, and wherein the organism is capable of mixotrophic metabolism of at least one gaseous substrate in the GS and at least one substrate in the AS. The present disclosure also describes a process wherein said fermentation operates at conditions to mixotrophically metabolize at least H 2 in the gaseous stream and glycerol and lactic acid in the aqueous stream. The present disclosure also describes a system for producing a fermentation or bio-derived product.
Abstract translation: 本公开描述了用于生产产物的生物催化方法，包括提供包含至少一种可发酵底物的水性流（AS）和包含CO 2中的至少一种的气态流（GS） 甲烷和/或CO到发酵区，其中所述GS和AS流任选地被接触和/或混合; 所述发酵区包含至少一种能够代谢AS底物和GS底物的生物体，其中所述发酵在使所述GS中的至少一种气态底物与所述AS中的至少一种底物混合营养代谢的条件下操作，产生所述产物。 本公开还描述了包含AS，GS和生物体的组合物，其中所述生物体或其等同物或工程等同物是甲烷氧化菌或氢代谢或CO代谢化学无机生物体，并且其中所述生物体能够混养 GS中的至少一种气态底物和AS中的至少一种底物的代谢。 本发明还描述了一种方法，其中所述发酵在使气态流中的至少H 2和甘油和水性流中的乳酸混合营养代谢的条件下操作。 本公开还描述了用于生产发酵或生物衍生产品的系统。
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Patent Agency Ranking
公开(公告)号：WO2017143194A3
公开(公告)日：2017-08-24
申请号：PCT/US2017/018375
申请日：2017-02-17
Inventor： SMITH, Gary , CONRADIE, Alex, Van Eck , KIRBY, Gregory, S. , PEARLMAN, Paul, S.
Abstract: Biocatalytic processes for producing a product wherein an aqueous stream comprising at least one fermentable substrate and/or a gaseous stream comprising at least one of CO 2 /H 2 , H 2 , methane, and/or CO are povided to a fermentation zone comprising at least one organism capable of metabolizing a substance present in one of the streams. The fermentation may operate at conditions to mixotrophically metabolize at least one gaseous substrate and at least one substrate present in the aqueous stream.
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公开(公告)号：WO2019245895A1
公开(公告)日：2019-12-26
申请号：PCT/US2019/037157
申请日：2019-06-14
Inventor： SMITH, Gary , PEARLMAN, Paul, S. , KIRBY, Gregory, S.
IPC: C12P7/04
Abstract: Methods, systems and compositions for producing at least one light-boiling, volatile, organic product using at least a portion of one or more carbon containing substances from a non-biosynthetic process in a biosynthetic process are provided. These methods, systems and compositions are useful in reducing waste treatment load of carbon containing chemical process waste streams.
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公开(公告)号：WO2019089711A1
公开(公告)日：2019-05-09
申请号：PCT/US2018/058381
申请日：2018-10-31
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： PEARLMAN, Paul, S. , ROJAS, Hugo, Federico, Cueto , SMITH, Gary , KIRBY, Gregory, S.
CPC classification number: A23K10/12 , A23K20/10 , A23K20/105 , A23K20/147 , A23K50/10 , A23K50/80 , C12N1/20 , C12N9/0006 , C12N9/1029 , C12N15/102
Abstract: Nutritive compositions containing an organism having attenuated or no poly (3-hydroxybutyrate) production are provided. These nutritive compositions are useful as feed, such as animal feed and feed additives for ruminants, non-ruminants and aquaculture, etc. Materials and methods for production of these organisms are provided.
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6.发明申请PROCESS FOR SEPARATION OF DIAMINES AND/OR OMEGA-AMINOACIDS FROM A FEED MIXTURE 审中-公开从进料混合物中分离DIAMINES和/或OMEGA-AMINOACIDS的方法
公开(公告)号：WO2016164767A1
公开(公告)日：2016-10-13
申请号：PCT/US2016/026712
申请日：2016-04-08
Applicant: INVISTA NORTH AMERICA S.A.R.L. , PEARLMAN, Paul
Inventor： PEARLMAN, Paul , SMITH, Gary , KIRBY, Gregory, S.
IPC: B01D15/18 , C07C209/82 , C07C227/38 , C07C211/12 , C07C229/08
CPC classification number: B01D15/185 , B01D15/1892 , C07C209/82 , C07C209/86 , C07C211/09 , C07C213/10 , C07C227/38 , C07C227/40 , C12P13/001 , C12P13/005 , C07C211/12 , C07C229/08
Abstract: The present disclosure relates to methods for separating at least one amine chosen from diamines and omega-aminoacids from a feed mixture using a simulated moving bed (SMB) adsorptive technology.
Abstract translation: 本公开涉及使用模拟移动床（SMB）吸附技术从进料混合物中分离选自二胺和ω-氨基酸的至少一种胺的方法。
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公开(公告)号：EP3417066A2
公开(公告)日：2018-12-26
申请号：EP17708117.1
申请日：2017-02-17
Inventor： SMITH, Gary , CONRADIE, Alex, Van Eck , KIRBY, Gregory, S. , PEARLMAN, Paul, S.
CPC classification number: C12P13/001 , C12M29/00 , C12M41/00 , C12N1/20 , C12P5/00 , C12P5/007 , C12P5/02 , C12P7/065 , C12P7/24 , C12P7/625 , C12P13/00 , C25B1/04 , F01D15/10 , F01K7/16 , F01K11/02 , F05D2220/31 , Y02E50/17 , Y02E50/343 , Y02E60/366
Abstract: The present disclosure describes biocatalytic processes for producing a product, comprising providing an aqueous stream (AS) comprising at least one fermentable substrate and a gaseous stream (GS) comprising at least one of CO2/H2, H2, methane, and/or CO to a fermentation zone, wherein the GS and AS stream are optionally contacted and/or mixed; the fermentation zone comprising at least one organism capable of metabolizing an AS substrate and a GS substrate, wherein the fermentation operates at conditions to mixotrophically metabolize at least one gaseous substrate in the GS and at least one substrate in the AS, producing the product. The present disclosure also describes compositions comprising an AS, a GS, and an organism, wherein the organism or an equivalent or engineered equivalent thereof is a methanotroph or a hydrogen-metabolizing or CO-metabolizing chemolithotrophic organism, and wherein the organism is capable of mixotrophic metabolism of at least one gaseous substrate in the GS and at least one substrate in the AS. The present disclosure also describes a process wherein said fermentation operates at conditions to mixotrophically metabolize at least H2 in the gaseous stream and glycerol and lactic acid in the aqueous stream. The present disclosure also describes a system for producing a fermentation or bio-derived product.
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