公开(公告)号：EP1196167A1

公开(公告)日：2002-04-17

申请号：EP00948576.4

申请日：2000-06-30

Applicant: Lipton, Stuart A.

Inventor： Lipton, Stuart A.

IPC: A61K31/40 ,  A61K31/44 ,  A61K31/415

CPC classification number: A61K31/506 ,  A61K31/00 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/4545

Abstract: The invention relates to a method of reducing neuronal injury or apoptosis including administering to a patient in need thereof an effective amount of a p38 mitogen-activated protein kinase (MAPK) inhibitor. Methods of treating an HIV-mediated dementia, glaucoma, or other neurodegenerative disorders are also disclosed.

公开(公告)号：EP1196167B1

公开(公告)日：2006-04-19

申请号：EP00948576.4

申请日：2000-06-30

Applicant: Lipton, Stuart A.

Inventor： Lipton, Stuart A.

IPC: A61K31/40 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/506 ,  A61K31/415 ,  A61K31/4545 ,  A61K31/00

CPC classification number: A61K31/506 ,  A61K31/00 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/4545

Abstract: The invention relates to a method of reducing neuronal injury or apoptosis including administering to a patient in need thereof an effective amount of a p38 mitogen-activated protein kinase (MAPK) inhibitor. Methods of treating an HIV-mediated dementia, glaucoma, or other neurodegenerative disorders are also disclosed.