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公开(公告)号：WO2006039360B1
公开(公告)日：2007-05-03
申请号：PCT/US2005034903
申请日：2005-09-29
Applicant: UNIV DELAWARE , MATERIALS RES SERVICES , RABOLT JOHN F , TSAO MEI-WEI
Inventor： RABOLT JOHN F , TSAO MEI-WEI
CPC classification number: A61B3/10 , A61B5/0059 , A61B5/14546 , G01J3/02 , G01J3/0208 , G01J3/021 , G01J3/0218 , G01J3/0294 , G01J3/04 , G01J3/108 , G01J3/14 , G01J3/2803 , G01J2003/2813 , G01N21/35 , G01N21/3504
Abstract: A method for detecting disease in a patient includes providing infrared (IR) light and coupling the IR light through direct lens coupling or through a first group of one or more optical fibers. IR light is reflected from a portion of the patient and collected by a lens arrangement or a second group of one or more optical fibers. The reflected IR light is dispersed into its spectrum which is detected and analyzed. An apparatus suitable for diagnosing a disease in a patient includes an IR light source and optical fiber or direct lens coupling of IR light onto a body part or fluid of the patient. Reflected light from the patient is optically dispersed using a prism or grating. An IR focal plane array receives the optically dispersed light. The spectrum of the reflected IR light is used to provide a diagnosis of disease in the patient by identifying various disease markers or chemical fingerprints. The method and apparatus are capable of non-invasively detecting disease markers in a patient.
Abstract translation: 用于检测患者疾病的方法包括提供红外（IR）光并通过直接透镜耦合或通过第一组一根或多根光纤耦合IR光。 IR光从患者的一部分反射并由透镜装置或第二组一根或多根光纤收集。 反射的红外光被分散到其光谱中，该光谱被检测和分析。 适用于诊断患者疾病的装置包括IR光源和光纤或将IR光直接连接到患者的身体部位或液体上的直接透镜。 来自患者的反射光使用棱镜或光栅进行光学分散。 IR焦平面阵列接收光学分散的光。 反射红外光的光谱用于通过识别各种疾病标志物或化学指纹来提供患者疾病的诊断。 该方法和装置能够非侵入性地检测患者中的疾病标志物。
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公开(公告)号：WO2006039360A3
公开(公告)日：2007-03-29
申请号：PCT/US2005034903
申请日：2005-09-29
Applicant: UNIV DELAWARE , MATERIALS RES SERVICES , RABOLT JOHN F , TSAO MEI-WEI
Inventor： RABOLT JOHN F , TSAO MEI-WEI
CPC classification number: A61B3/10 , A61B5/0059 , A61B5/14546 , G01J3/02 , G01J3/0208 , G01J3/021 , G01J3/0218 , G01J3/0294 , G01J3/04 , G01J3/108 , G01J3/14 , G01J3/2803 , G01J2003/2813 , G01N21/35 , G01N21/3504
Abstract: A method for detecting disease in a patient includes providing infrared (IR) light and coupling the IR light through direct lens coupling or through a first group of one or more optical fibers. IR light is reflected from a portion of the patient and collected by a lens arrangement or a second group of one or more optical fibers. The reflected IR light is dispersed into its spectrum which is detected and analyzed. An apparatus suitable for diagnosing a disease in a patient includes an IR light source and optical fiber or direct lens coupling of IR light onto a body part or fluid of the patient. Reflected light from the patient is optically dispersed using a prism or grating. An IR focal plane array receives the optically dispersed light. The spectrum of the reflected IR light is used to provide a diagnosis of disease in the patient by identifying various disease markers or chemical fingerprints. The method and apparatus are capable of non-invasively detecting disease markers in a patient.
Abstract translation: 一种检测患者疾病的方法包括提供红外（IR）光并通过直接透镜耦合或通过第一组一根或多根光纤耦合红外光。 IR光从患者的一部分反射并且由透镜装置或第二组一个或多个光纤收集。 反射的红外光被分散到其被检测和分析的光谱中。 适用于诊断患者疾病的设备包括IR光源和光纤或将IR光直接透镜耦合到患者的身体部分或流体上。 使用棱镜或光栅将来自患者的反射光进行光学分散。 红外焦平面阵列接收光分散的光。 反射的IR光谱用于通过鉴定各种疾病标志物或化学指纹来提供患者疾病的诊断。 该方法和装置能够无创地检测患者中的疾病标志物。
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Patent Agency Ranking
公开(公告)号：CA2582097A1
公开(公告)日：2006-04-13
申请号：CA2582097
申请日：2005-09-29
Applicant: UNIV DELAWARE , MATERIALS RES SERVICES
Inventor： RABOLT JOHN F , TSAO MEI-WEI
Abstract: A method for detecting disease in a patient includes providing infrared (IR) light and coupling the IR light through direct lens coupling or through a first group of one or more optical fibers. IR light is reflected from a portion of the patient and collected by a lens arrangement or a second group of one or more optical fibers. The reflected IR light is dispersed into its spectrum which is detected and analyzed. An apparatus suitable for diagnosing a disease in a patient includes an IR light source and optical fiber or direct lens coupling of IR light onto a body part or fluid of the patient. Reflected light from the patient is optically dispersed using a prism or grating. An IR focal plane array receives the optically dispersed light. The spectrum of the reflected IR light is used to provide a diagnosis of disease in the patient by identifying various disease markers or chemical fingerprints. The method and apparatus are capable of non-invasively detecting disease markers in a patient.
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公开(公告)号：EP1793732A4
公开(公告)日：2009-11-11
申请号：EP05801847
申请日：2005-09-29
Applicant: UNIV DELAWARE , MATERIALS RES SERVICES
Inventor： RABOLT JOHN F , TSAO MEI-WEI
CPC classification number: A61B3/10 , A61B5/0059 , A61B5/14546 , G01J3/02 , G01J3/0208 , G01J3/021 , G01J3/0218 , G01J3/0294 , G01J3/04 , G01J3/108 , G01J3/14 , G01J3/2803 , G01J2003/2813 , G01N21/35 , G01N21/3504
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公开(公告)号：AU2006200758C1
公开(公告)日：2006-03-16
申请号：AU2006200758
申请日：2006-02-23
Applicant: UNIV DELAWARE
Inventor： ELMORE DOUGLAS L , TSAO MEI-WEI , RABOLT JOHN F
IPC: G01J3/40
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公开(公告)号：AU2005292074A1
公开(公告)日：2006-04-13
申请号：AU2005292074
申请日：2005-09-29
Applicant: MATERIALS RES SERVICES , UNIV DELAWARE
Inventor： TSAO MEI-WEI , RABOLT JOHN F
IPC: G01C3/14
Abstract: A method for detecting disease in a patient includes providing infrared (IR) light and coupling the IR light through direct lens coupling or through a first group of one or more optical fibers. IR light is reflected from a portion of the patient and collected by a lens arrangement or a second group of one or more optical fibers. The reflected IR light is dispersed into its spectrum which is detected and analyzed. An apparatus suitable for diagnosing a disease in a patient includes an IR light source and optical fiber or direct lens coupling of IR light onto a body part or fluid of the patient. Reflected light from the patient is optically dispersed using a prism or grating. An IR focal plane array receives the optically dispersed light. The spectrum of the reflected IR light is used to provide a diagnosis of disease in the patient by identifying various disease markers or chemical fingerprints. The method and apparatus are capable of non-invasively detecting disease markers in a patient.
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公开(公告)号：AU2002211338B2
公开(公告)日：2005-09-29
申请号：AU2002211338
申请日：2001-10-01
Applicant: UNIV DELAWARE
Inventor： RABOLT JOHN F , TSAO MEI-WEI
Abstract: An apparatus and method capable of providing IR spectral information using IR absorption phenomena requires no moving parts or Fourier Transform during operation. IR spectral information and chemical analysis of a sample in a sample containing functional groups is determined by using an IR source (310), a sampling accessory (330) for positioning the sample volume, an optically dispersive element (350), a focal plane array (FPA) arranged to detect the dispersed light beam, and a processor (380) and display (390) to control the FPA, and display an IR spectrograph. Fiber-optic coupling allows remote sensing, and portability, reliability, and ruggedness is enhanced due to the no-moving part construction. Use of the apparatus and method has broad industrial and environmental application, including measurement of thickness and chemical composition of various films, coatings, and liquids, and may also be used in a real-time sensing of hazardous materials, including chemical and biological warface agents.
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