TARGET-SUBSTANCE DETECTION APPARATUS AND METHOD
    2.
    发明公开
    TARGET-SUBSTANCE DETECTION APPARATUS AND METHOD 有权
    ZIELSUBSTANZDETEKTIONSVORRICHTUNG UND -VERFAHREN

    公开(公告)号:EP2993460A4

    公开(公告)日:2017-04-26

    申请号:EP14804538

    申请日:2014-05-30

    Abstract: A detection device (100) detects an analyte that may be contained in a specimen. The detection device (100) includes a plurality of gold nanoparticles, an optical trapping light source (101), an illumination light source (102), an objective lens (103), an image pick-up device (108), and a computation unit (106). The plurality of gold nanoparticles are each modified with a probe DNA allowing the analyte to specifically adhere thereto. The optical trapping light source (101) emits polarized light for assembling the plurality of gold nanoparticles together. The objective lens (103) focuses and introduces the polarized light into a liquid containing a specimen and the plurality of gold nanoparticles. The image pick-up device (108) receives light from the liquid. The computation unit (106) detects an analyte based on a signal received from the image pick-up device (108).

    Abstract translation: 检测装置(100)检测可能包含在样本中的分析物。 检测装置(100)包括多个金纳米粒子,光俘获光源(101),照明光源(102),物镜(103),图像拾取装置(108)和计算机 单元(106)。 多个金纳米颗粒各自用允许分析物特异性粘附于其上的探针DNA修饰。 光俘获光源(101)发射用于将多个金纳米颗粒组装在一起的偏振光。 物镜(103)聚焦并将偏振光引入含有样本和多个金纳米颗粒的液体中。 图像拾取装置(108)接收来自液体的光。 计算单元(106)基于从图像拾取装置(108)接收的信号来检测分析物。

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