公开(公告)号：WO2008036533A2

公开(公告)日：2008-03-27

申请号：PCT/US2007078206

申请日：2007-09-11

Applicant: UNIV WASHINGTON

Inventor： FAUVER MARK E ,  SEIBEL ERIC J ,  MEYER MICHAEL G ,  NELSON ALAN C ,  RAHN RICHARD J ,  NEUMANN THOMAS ,  JOHNSON ROGER H

IPC: E01C19/38

CPC classification number: G01N21/4795 ,  G01N15/147 ,  G01N15/1475

Abstract: A method for tracking an object (414) in a system for optical tomography, where the object (414) is contained in a tube (410) having a center of rotation (422), the object (414) has a centroid (415), and the object (414) is offset from the center of rotation. Image data is acquired by scanning the object (414) through an extended depth of field while the object (414) is being rotated. A distance value of the object (414) centroid (415) from the center of rotation is calculated from the image data, A rotation angle value (ßR) is caicuiated from the acquired image data. An extent of the object (414) is determined limiting the extended depth of field being scanned to less than or equal to the extent of the object (414) so as to increase image resolution in a resultant pseudoprojection image.

Abstract translation: 一种用于追踪光学断层摄影系统中的物体（414）的方法，其中物体（414）被包含在具有旋转中心（422）的管（410）中，物体（414）具有质心（415） ，并且物体（414）偏离旋转中心。 通过在对象（414）被旋转时通过扩展景深扫描对象（414）来获取图像数据。 根据图像数据计算出旋转中心的物体（414）质心（415）的距离值，从所获取的图像数据中减去旋转角度值（ßR）。 确定对象（414）的范围，将正被扫描的扩展景深限制为小于或等于对象（414）的范围，以便增加所得伪投影图像中的图像分辨率。

公开(公告)号：WO2005050558A3

公开(公告)日：2007-05-31

申请号：PCT/US2004037323

申请日：2004-11-08

Applicant: UNIV WASHINGTON

Inventor： FAUVER MARK E ,  RAHN JOHN RICHARD ,  SEIBEL ERIC J ,  NELSON ALAN C

IPC: A61B5/05 ,  G01N21/17 ,  A61B10/00 ,  G01N15/14 ,  G01N21/03 ,  G01N21/05 ,  G01N21/21 ,  G01N21/47 ,  G06T20060101

CPC classification number: G01N15/1475 ,  G01N15/1468 ,  G01N15/147 ,  G01N21/05 ,  G01N21/4795 ,  G01N2015/1006 ,  G01N2015/1075 ,  G01N2015/1447 ,  G01N2021/0346 ,  G01N2021/1787 ,  G01N2201/0813 ,  G01N2223/612 ,  G06T11/006 ,  G06T2211/421

Abstract: A system for optical imaging of a thick specimen (1) that permits rapid acquisition of data necessary for tomographic reconstruction of the three-dimensional (3D) image. One method involves the scanning of the focal plane of an imaging system (60, 61) and integrating the range of focal planes onto a detector (43). The focal plane of an optical imaging system (60, 61) is scanned along the axis perpendicular to said plane through the thickness of a specimen (1) during a single detector exposure. Secondly, methods for reducing light scatter when using illumination point sources (11) are presented. Both approaches yield shadowgrams. This process is repeated from multiple perspectives, either in series using a single illumination/detection subsystem, or in parallel using several illumination/detection subsystems. A set of pseudo-projections is generated, which are input to a three dimensional tomographic image reconstruction algorithm (74).

Abstract translation: 一种厚样本（1）的光学成像系统，其允许快速获取三维（3D）图像的层析成像所需的数据。 一种方法包括扫描成像系统（60,61）的焦平面并将焦平面的范围集成到检测器（43）上。 在单个检测器曝光期间，光学成像系统（60,61）的焦平面沿垂直于所述平面的轴扫描样本（1）的厚度。 其次，提出了当使用照明点源（11）时减少光散射的方法。 两种方法产生阴影图。 该过程从多个角度重复，使用单个照明/检测子系统串联使用，或者使用几个照明/检测子系统并行重复。 产生一组伪投影，其被输入到三维断层图像重建算法（74）。

公开(公告)号：CA2663744C

公开(公告)日：2016-04-26

申请号：CA2663744

申请日：2007-09-11

Applicant: UNIV WASHINGTON ,  VISIONGATE INC

Inventor： FAUVER MARK E ,  SEIBEL ERIC J ,  MEYER MICHAEL G ,  NELSON ALAN C ,  RAHN RICHARD J ,  NEUMANN THOMAS ,  JOHNSON ROGER H

IPC: G01N15/10 ,  C12M1/34 ,  G01B11/24

Abstract: A method for tracking an object (414) in a system for optical tomography, where the object (414) is contained in a tube (410) having a center of rotation (422), the object (414) has a centroid (415), and the object (414) is offset from the center of rotation. Image data is acquired by scanning the object (414) through an extended depth of field while the object (414) is being rotated. A distance value of the object (414) centroid (415) from the center of rotation is calculated from the image data, A rotation angle value (.beta.R) is caicuiated from the acquired image data. An extent of the object (414) is determined limiting the extended depth of field being scanned to less than or equal to the extent of the object (414) so as to increase image resolution in a resultant pseudoprojection image.

公开(公告)号：CA2663744A1

公开(公告)日：2008-03-27

申请号：CA2663744

申请日：2007-09-11

Applicant: UNIV WASHINGTON

Inventor： JOHNSON ROGER H ,  NEUMANN THOMAS ,  MEYER MICHAEL G ,  FAUVER MARK E ,  SEIBEL ERIC J ,  NELSON ALAN C ,  RAHN RICHARD J

IPC: G06K9/00

Abstract: A method for tracking an object (414) in a system for optical tomography, where the object (414) is contained in a tube (410) having a center of rota tion (422), the object (414) has a centroid (415), and the object (414) is o ffset from the center of rotation. Image data is acquired by scanning the ob ject (414) through an extended depth of field while the object (414) is bein g rotated. A distance value of the object (414) centroid (415) from the cent er of rotation is calculated from the image data, A rotation angle value (.b eta.R) is caicuiated from the acquired image data. An extent of the object ( 414) is determined limiting the extended depth of field being scanned to les s than or equal to the extent of the object (414) so as to increase image re solution in a resultant pseudoprojection image.

公开(公告)号：AU2007297473B2

公开(公告)日：2013-11-14

申请号：AU2007297473

申请日：2007-09-11

Applicant: UNIV WASHINGTON ,  VISIONGATE INC

Inventor： SEIBEL ERIC J ,  NEUMANN THOMAS ,  NELSON ALAN C ,  MEYER MICHAEL G ,  FAUVER MARK E ,  RAHN RICHARD J ,  JOHNSON ROGER H

IPC: G06K9/00

Abstract: A method for tracking an object (414) in a system for optical tomography, where the object (414) is contained in a tube (410) having a center of rotation (422), the object (414) has a centroid (415), and the object (414) is offset from the center of rotation. Image data is acquired by scanning the object (414) through an extended depth of field while the object (414) is being rotated. A distance value of the object (414) centroid (415) from the center of rotation is calculated from the image data, A rotation angle value (&bgr;R) is caicuiated from the acquired image data. An extent of the object (414) is determined limiting the extended depth of field being scanned to less than or equal to the extent of the object (414) so as to increase image resolution in a resultant pseudoprojection image.

公开(公告)号：AU2007297473A1

公开(公告)日：2008-03-27

申请号：AU2007297473

申请日：2007-09-11

Applicant: UNIV WASHINGTON

Inventor： NELSON ALAN C ,  JOHNSON ROGER H ,  FAUVER MARK E ,  SEIBEL ERIC J ,  NEUMANN THOMAS ,  RAHN RICHARD J ,  MEYER MICHAEL G

IPC: E01C19/38 ,  G06K9/00

Abstract: An optical tomography system for imaging an object of interest including a light source for illuminating the object of interest with a plurality of radiation beams. The object of interest is held within an object containing tube such that it is illuminated by the plurality of radiation beams to produce emerging radiation from the object containing tube, a detector array is located to receive the emerging radiation and produce imaging data used by a mechanism for tracking the object of interest.