公开(公告)号：WO2003099269A1

公开(公告)日：2003-12-04

申请号：PCT/KR2002/001209

申请日：2002-06-25

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  SCIGENIC CO., LTD. ,  KIM, Dong-Jin ,  SHIN, Kye-Jung ,  YU, Jaehoon ,  LEE, Hee-Sul

Inventor： KIM, Dong-Jin ,  SHIN, Kye-Jung ,  YU, Jaehoon ,  LEE, Hee-Sul

IPC: A61K31/195

CPC classification number: C07C229/44 ,  C07C45/71 ,  C07C47/575 ,  C07C59/68 ,  C07C67/343 ,  C07C69/734

Abstract: The present invention relates to cinnamic acid dimers, their preparation and the use thereof for treating neurodegenerative disease, which have excellent effect on enhancing the learning and memory-retention ability in vivo and have fewer side-effects by showing no hormone properties, even when administered for a long period of time, and thus which can be used for neurodegenerative disease including dementia.

Abstract translation: 本发明涉及肉桂酸二聚体及其制备方法及其用于治疗神经变性疾病的用途，其对于增强体内的学习和记忆保持能力具有优异的效果，并且即使在施用时也不显示激素性质，具有较少的副作用 长时间，因此可用于包括痴呆的神经变性疾病。

公开(公告)号：WO2003093194A1

公开(公告)日：2003-11-13

申请号：PCT/KR2003/000858

申请日：2003-04-28

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  LEE, Hae-Weon ,  KIM, Joo-Sun ,  LEE, Jong-Ho ,  SONG, Hue-Sup ,  SHIN, Hyun-Ick

Inventor： LEE, Hae-Weon ,  KIM, Joo-Sun ,  LEE, Jong-Ho ,  SONG, Hue-Sup ,  SHIN, Hyun-Ick

IPC: C04B35/573

CPC classification number: C04B35/63 ,  B82Y30/00 ,  C04B35/573 ,  C04B35/634 ,  C04B2235/3826 ,  C04B2235/422 ,  C04B2235/428 ,  C04B2235/48 ,  C04B2235/5436 ,  C04B2235/5454 ,  C04B2235/604 ,  C04B2235/608 ,  C04B2235/77

Abstract: A method of manufacturing reaction-bonded silicon carbide is disclosed , which comprises; preparing a silicon providing body including silicon powder and a binder; preparing a compact body of silicon carbide and carbon; keeping the silicon providing body contacting the compact body; and heating the contacted bodies at temperature higher than the melting point of silicon in vacuum or inert atmosphere so that fused silicon in the silicon providing body can be infiltrated into the compact body.

Abstract translation: 公开了一种制造反应粘合碳化硅的方法，其包括： 制备包括硅粉和粘合剂的硅提供体; 制备碳化硅和碳的紧凑​​体; 保持硅提供体接触紧凑体; 并且在真空或惰性气氛中高于硅熔点的温度加热接触体，使得硅提供体中的熔融硅可被渗入到紧凑体内。

公开(公告)号：WO2003093180A1

公开(公告)日：2003-11-13

申请号：PCT/KR2002/000822

申请日：2002-05-02

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  BAE, Jae-Ho ,  AHN, Kyu-Hong ,  LEE, Seock-Heon

Inventor： BAE, Jae-Ho ,  AHN, Kyu-Hong ,  LEE, Seock-Heon

IPC: C02F3/34

CPC classification number: C02F3/2806 ,  C02F3/10 ,  C02F3/345 ,  Y02W10/15

Abstract: The present invention relates to a biological denitrification apparatus and a denitrification method using a fluidized-bed reactor filled with elemental sulfur. The apparatus comprises: a reactor filled with elemental sulfur and limestone therein; an inlet port at a lower portion of the reactor for introducing the wastewater to flow from the lower portion to an upper portion of the reactor; a treated water sedimentation basin over the reactor for collecting the introduced water after passing through the reactor; a treated water recycle line between the treated water sedimentation basin and the inlet port of the reactor for recycling the treated water from the treated water sedimentation basin to the inlet port of the reactor; a pump mounted to an end of the treated water recycle line for increasing the flow rate of the recycled water; and a T-shaped precipitator at one end of the recycle line for precipitating suspended solids such as microbes contained in the treated water recycled to the reactor, in which the treated water sedimentation basin has a diameter at least twice that of the reactor in order to function as a sedimentation basin.

Abstract translation: 本发明涉及使用填充有元素硫的流化床反应器的生物脱氮装置和脱氮方法。 该装置包括：填充有元素硫和石灰石的反应器; 反应器下部的入口，用于引入废水从反应器的下部流向上部; 经过反应器处理的水沉淀池，用于在通过反应器之后收集引入的水; 经过处理的水沉淀池和反应器入口之间的经处理的水循环管线，用于将经处理的水从经处理的水沉淀池再循环到反应器的入口; 安装在经处理的水循环管线末端的泵，用于增加循环水的流量; 以及在再循环管线的一端的T形除尘器，用于沉淀循环到反应器中的处理水中所含的悬浮固体如微生物，其中经处理的水沉降池的直径至少为反应器的两倍，以便 作为沉积盆地。

公开(公告)号：WO2003072315A1

公开(公告)日：2003-09-04

申请号：PCT/KR2002/000710

申请日：2002-04-18

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  KIM, Mun-Sang ,  KANG, Sung-Chul ,  CHO, Chang-Hyun ,  SHIN, Hyun-Oh ,  KIM, Jea-Sun ,  HWANG, Yo-Ha

Inventor： KIM, Mun-Sang ,  KANG, Sung-Chul ,  CHO, Chang-Hyun ,  SHIN, Hyun-Oh ,  KIM, Jea-Sun ,  HWANG, Yo-Ha

IPC: B25J13/00

CPC classification number: B25J17/0208 ,  B25J9/1015 ,  B25J9/1633 ,  B25J9/1697 ,  B25J19/0091 ,  G05B2219/39527 ,  G05B2219/39577 ,  G05B2219/40557 ,  G05B2219/40609

Abstract: A working robot, which is able to perform a required operation by locating a tool on a working position of a moving object, comprises a robot body moving with the object according to the movement of the object with more than one degree of freedom; an actuator mounted on a free end of the robot body and including a tool mounting unit, on which the tool is mounted, connected by a passive joint which reacts passively to small displacement of the object for locating the tool on the working position; and a control device for controlling the robot body, the actuator, and the tool.

Abstract translation: 能够通过将工具定位在移动物体的工作位置上而能够进行所需操作的工作机器人包括：机器人主体，根据物体的移动具有多于一个自由度; 安装在所述机器人主体的自由端上的致动器，并且包括工具安装单元，所述工具安装在所述工具安装单元上，所述工具安装单元通过被动接头连接，所述被动接头被动地对所述物体的小位移进行反应， 以及用于控制机器人主体，致动器和工具的控制装置。

公开(公告)号：WO2003044034A1

公开(公告)日：2003-05-30

申请号：PCT/KR2001/002101

申请日：2001-12-05

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  YU, Jaehoon ,  LEE, Jongkook ,  KWON, Miyun ,  SHIN, Kye-Jung

Inventor： YU, Jaehoon ,  LEE, Jongkook ,  KWON, Miyun ,  SHIN, Kye-Jung

IPC: C07H15/232

CPC classification number: C07H5/10 ,  C07H15/232

Abstract: The present invention relates to heterodimeric conjugates of neomycin-chloramphenicol of formula 1, their preparation and their use. Because of their heterodimeric structure, they can recognize both stem and loop of RNA motif and show binding ability to a certain RNA such that they have an enhanced pharmaceutical efficacy and reduced side effect which can be caused by non-specific drugs. For these reasons, they can be effectively used as an antiviral agent, an antibacterial agent or an anticancer drugs.

Abstract translation: 本发明涉及式1的新霉素 - 氯霉素的异二聚体缀合物，其制备及其用途。 由于它们的异二聚体结构，它们可以识别RNA基序的茎和环，并且显示出对某些RNA的结合能力，使得它们具有增强的药物功效并且可以由非特异性药物引起的副作用降低。 由于这些原因，它们可以有效地用作抗病毒剂，抗菌剂或抗癌药物。

公开(公告)号：WO2003022265A1

公开(公告)日：2003-03-20

申请号：PCT/KR2001/001614

申请日：2001-09-26

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  DAEHWA PHARM. CO., LTD. ,  CHUNG, Hesson ,  JEONG, Seo, Young ,  KWON, Ick, Chan ,  PARK, Jae, Hyung ,  CHUNG, Jin, Wook ,  KIM, Young, Man ,  LEE, In-Hyun

Inventor： CHUNG, Hesson ,  JEONG, Seo, Young ,  KWON, Ick, Chan ,  PARK, Jae, Hyung ,  CHUNG, Jin, Wook ,  KIM, Young, Man ,  LEE, In-Hyun

IPC: A61K31/335

CPC classification number: A61K49/0452 ,  A61K9/0019 ,  A61K31/337 ,  A61K47/44

Abstract: Oily paclitaxel composition and formulation for chemoembolization and preparation method thereof solubilizing paclitaxel in an oily contrast medium. The composition of the present invention solubilizes paclitaxel and has an advantage of delivering anticancer drug to the target cells by chemoembolization since it is possible to visualize the blood vessel during the chemoembolization process.

Abstract translation: 油性紫杉醇组合物和化疗栓塞制剂及其在油性造影剂中增溶紫杉醇的制备方法。 本发明的组合物溶解紫杉醇，并且具有通过化学栓塞将抗癌药物递送至靶细胞的优点，因为在化学栓塞过程中可以使血管可视化。

公开(公告)号：WO1998029100A1

公开(公告)日：1998-07-09

申请号：PCT/KR1997000289

申请日：1997-12-31

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  JEONG, Seo, Young ,  CHOI, Kuiwon ,  KWON, Ick-Chan ,  KIM, Yong-Hee ,  CHOI, Jae, Bong ,  LEE, Kyu, Back

Inventor： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

IPC: A61K09/19

CPC classification number: A61K9/7007 ,  Y10S514/953 ,  Y10S514/964 ,  Y10S514/975

Abstract: A method of manufacturing a porous matrix-type drug delivery system is provided. It comprises the steps of: dispersing, stirring, and emulsifying an aqueous solution of a drug in an organic solvent having a polymer compound and a surface active agent solved therein; thereafter forming it into a desirable matrix shape; lyophilizing or drying it at a low temperature or room temperature until the matrix surface is hardened; and drying it again in order to remove the water and the organic solvent.

Abstract translation: 提供一种制造多孔基质型药物递送系统的方法。 其包括以下步骤：将药物的水溶液分散，搅拌和乳化在溶解有高分子化合物和表面活性剂的有机溶剂中; 然后将其形成为期望的矩阵形状; 在低温或室温下冻干或干燥，直到基质表面硬化; 并再次干燥以除去水和有机溶剂。

公开(公告)号：WO1997036949A1

公开(公告)日：1997-10-09

申请号：PCT/KR1997000055

申请日：1997-04-01

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  PACIFIC CORPORATION ,  JEONG, Seo, Young ,  KWON, Ick, Chan ,  KIM, Yong-Hee

Inventor： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  PACIFIC CORPORATION

IPC: C08J03/00

CPC classification number: A61K9/1694 ,  A61K9/1647 ,  C08J3/16

Abstract: A preparation method for biodegradable polymeric microspheres using a solvent extraction method and a preparation method for biodegradable polymeric microspheres for treating a local inflammation disease using the same which are capable of effectively curing ozena such as sinusitis and a middle ear inflammation. Since a non-solvant of the polymer is added into an outer aqueous phase in advance, the solidification of the polymer is implemented in a short time which, in turn, improves the encapsulation efficiency of the therapeutic agent used.

Abstract translation: 使用溶剂萃取方法的生物可降解聚合物微球的制备方法和用于治疗局部炎症疾病的生物可降解聚合物微球的制备方法，其能够有效地治愈诸如鼻窦炎和中耳炎的氧化物。 由于预先将聚合物的非溶剂加入到外部水相中，所以聚合物的凝固在短时间内进行，这又提高了所用治疗剂的包封效率。

公开(公告)号：WO1996037094A1

公开(公告)日：1996-11-28

申请号：PCT/KR1996000074

申请日：1996-05-22

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  LIU, Jang, Ryol ,  LEE, Kyung, Kwang ,  YU, Dae, Yeul ,  LEE, Mi, Hee

Inventor： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

IPC: A01H01/00

CPC classification number: C07K14/79 ,  C12N15/8283

Abstract: A process for the preparation of an antiviral plant, which comprises transforming a plant with an expression vector containing a lactoferrin(Lf) gene and culturing the transformed plant.

Abstract translation: 一种制备抗病毒植物的方法，其包括用含有乳铁蛋白（Lf）基因的表达载体转化植物并培养转化的植物。

公开(公告)号：WO2017184957A1

公开(公告)日：2017-10-26

申请号：PCT/US2017/028800

申请日：2017-04-21

Applicant: DREXEL UNIVERSITY ,  KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： GOGOTSI, Yury ,  ANASORI, Babak ,  ALHABEB, Mohamed, H. ,  HATTER, Christine, B. ,  KOO, Chong, Min ,  HONG, Soon Man ,  SHAHZAD, Faisal

IPC: H05K9/00 ,  G02B5/28

CPC classification number: H05K9/0088 ,  C01B32/921 ,  C01P2002/20 ,  C01P2002/72 ,  C01P2004/03 ,  C01P2004/04 ,  C01P2006/40 ,  H01B1/20 ,  H01L23/295 ,  H01L23/552 ,  H01L2924/3025 ,  H05K9/0084

Abstract: The present disclosure is directed to materials which provide electromagnetic shielding and methods of providing such electromagnetic shielding. In particular, the present disclosure describes the use of two-dimensional transition metal carbide, nitride, and carbonitride materials for this purpose.

Abstract translation: 本公开涉及提供电磁屏蔽的材料和提供这种电磁屏蔽的方法。 具体而言，本公开描述了二维过渡金属碳化物，氮化物和碳氮化物材料用于此目的的用途。