公开(公告)号：WO1992005696A1

公开(公告)日：1992-04-16

申请号：PCT/US1991006731

申请日：1991-09-20

Applicant: UNIVERSITY OF FLORIDA

Inventor： UNIVERSITY OF FLORIDA ,  GOLDBERG, Eugene, P. ,  YAHIAOUI, Ali

IPC: A01N01/02

CPC classification number: B05D3/068 ,  A61F2/14 ,  A61F2/16 ,  A61F2002/0086 ,  A61F2002/009 ,  A61L27/16 ,  A61L27/34 ,  A61L2400/18 ,  A61L2430/16 ,  B05D7/02 ,  G02B1/043 ,  Y10S623/901 ,  C08L51/00 ,  C08L39/06 ,  C08L33/14

Abstract: An improved method for modifying the surface of an ocular implant material (10) by the gamma or electron beam irradiation induced chemical graft coating thereon of a monomer comprising N-vinyl-pyrrolidone, 2-hydroxyethylmethacrylate or a mixture of the two to form a hydrophilic graft polymer coating, the improvement comprising pre-soaking the ocular implant material (10) in a monomer or a solution comprising a monomer prior to conducting the gamma- or electron beam-irradiation induced graft polymerization in a second solution of a monomer.

Abstract translation: 一种用于通过伽马或电子束照射诱导化学接枝涂覆在其上的包含N-乙烯基吡咯烷酮，甲基丙烯酸2-羟乙酯或两者的混合物的单体的眼部植入材料（10）的表面的改进方法，以形成亲水 接枝聚合物涂层，其改进包括在将单体或包含单体的溶液在进行在单体的第二溶液中的γ射线或电子束照射诱导的接枝聚合之前将眼睛植入材料（10）预浸泡。

公开(公告)号：WO1991017965A2

公开(公告)日：1991-11-28

申请号：PCT/US1991003516

申请日：1991-05-17

Applicant: UNIVERSITY OF FLORIDA

Inventor： UNIVERSITY OF FLORIDA ,  HENCH, Larry, L. ,  CLARK, Arthur, E. ,  LI, Rounan

IPC: C03C03/097

CPC classification number: A61L27/32 ,  A61F2310/00293 ,  A61F2310/00796 ,  A61L27/12 ,  C03C1/006 ,  C03C3/097 ,  C03C4/0007

Abstract: Sol-gel processing techniques are used to produce alkali-free bioactive glass compositions based on SiO2, CaO and P2O5. By varying the SiO2 content, a range of hydroxyapatite production rates can be obtained; conversely, varying the time of exposure to actual or simulated in vivo solutions permits use of a range of allowable proportions of SiO2. The sol-gel derived compositions can be chosen to achieve target values for thermal expansion coefficient, elastic modulus and volume electrical resistivity.

公开(公告)号：WO1990006056A1

公开(公告)日：1990-06-14

申请号：PCT/US1989005443

申请日：1989-12-01

Applicant: UNIVERSITY OF FLORIDA

Inventor： UNIVERSITY OF FLORIDA ,  BEWICK, Thomas, A.

IPC: A01N63/04

CPC classification number: C12R1/645 ,  A01N63/04

Abstract: The subject invention concerns a novel bioherbicide and its use to control a major weed found in many fields in the Southern United States and in the Caribbean. Specifically, a novel Colletotrichum isolate in an agricultural composition can be used to effectively control purple nutsedge without adversely affecting field crops. Further, the novel isolate in a mixture with other biocontrol agents can be used to control nutsedge and other undesired vegetation, such as Florida beggarweed, sicklepod, showy crotalaria and coffee senna.

Abstract translation: 本发明涉及一种新颖的生物除草剂及其用于控制​​在美国南部和加勒比南部许多领域中发现的主要杂草的用途。 具体来说，一种农业组合中的新颖的Colletotrichum分离物可用于有效地控制紫色坚果，而不会对田间作物产生不利影响。 此外，与其他生物防治剂的混合物中的新型分离物可以用于控制坚果和其他不期望的植物，例如佛罗里达乞丐，镰刀菌，波罗的海和咖啡番茄。

公开(公告)号：WO1990004364A1

公开(公告)日：1990-05-03

申请号：PCT/US1989004715

申请日：1989-10-23

Applicant: COOK INCORPORATED ,  UNIVERSITY OF FLORIDA

Inventor： COOK INCORPORATED ,  UNIVERSITY OF FLORIDA ,  MELKER, Richard, J. ,  GEAREN, Peter, F. ,  MILLER, Gary, J. ,  DeBRUYNE, Michael, P. ,  MOLITOR, Lisa

IPC: A61B17/34

CPC classification number: A61B17/3472 ,  A61B17/864 ,  A61B17/8811

Abstract: An intraosseous needle assembly includes an intraosseous needle (10) having a threaded shaft (12) with a passageway extending substantially therethrough, a solid and pointed tip (13) at one end thereof, the tip having a pair of concave identations (41), (42), creating cutting edges. At the opposite end of the shaft, or hub, the needle is adapted to couple with an appropriate gripping device. A handle is provided in the shape of a ball knob and is adapted to telescopically and grippingly receive the hub (11) of the needle. The hub and handle are both equipped with mutually engaging torque-transmitting surfaces.

Abstract translation: 骨内针组件包括具有螺纹轴（12）的骨内针（10），所述螺纹轴具有基本上穿过其延伸的通道，在其一端处具有实心尖尖（13），所述尖端具有一对凹形标记（41）， （42），创建切割刃。 在轴或轮毂的相对端，针适于与适当的夹紧装置连接。 手柄设置成球形旋钮的形状，并且适于伸缩地并且夹紧地容纳针的轮毂（11）。 轮毂和手柄均配有相互接合的扭矩传递表面。

公开(公告)号：WO1990003819A1

公开(公告)日：1990-04-19

申请号：PCT/US1989004296

申请日：1989-10-05

Applicant: UNIVERSITY OF FLORIDA

Inventor： UNIVERSITY OF FLORIDA ,  LAMPOTANG, Samsun ,  GRAVENSTEIN, Dietrich ,  GRAVENSTEIN, Joachim, S. ,  GRAVENSTEIN, Nikolaus ,  BANNER, Michael, J.

IPC: A61M16/00

CPC classification number: A61M16/0488 ,  A61M2016/0413 ,  A61M2230/432

Abstract: A monitor (1) for detecting CO2 content of a gas exiting a patient comprising a reservoir (2) containing a composition (3) having an initial pH in solution above about 3.8 and which changes color in solution in response to exposure to CO2, the reservoir (2) having an opening (4) for communication only with gas (5) exiting and entering the patient during intubation and a semipermeable membrane (6) which is permeable to CO2, the membrane separating the composition (3) from the exiting and entering gases (5).

Abstract translation: 一种用于检测离开患者的气体的CO 2含量的监测器（1），其包括储存器（2），所述储存器（2）含有溶液中的初始pH高于约3.8并且响应于暴露于CO 2而在溶液中变色的组合物（3） 储存器（2）具有仅用于在插管期间离开并进入患者的气体（5）的开口（4）和可渗透CO 2的半透膜（6），所述膜将组合物（3）与离开和/ 进入气体（5）。

公开(公告)号：WO1990002193A1

公开(公告)日：1990-03-08

申请号：PCT/US1989003753

申请日：1989-08-29

Applicant: UNIVERSITY OF FLORIDA

Inventor： UNIVERSITY OF FLORIDA ,  INGRAM, Lonnie, O. ,  CONWAY, Tyrrell ,  ALTERTHUM, Flavio

IPC: C12P07/06

CPC classification number: G06T1/00 ,  C12N15/52 ,  C12P7/065 ,  F25B2313/02731 ,  F25B2313/02732 ,  F25B2313/02741 ,  F25B2313/02743 ,  Y02E50/17

Abstract: A novel operon and plasmids comprising genes which code for the alcohol dehydrogenase and pyruvate decarboxylase activities of Zymomonas mobilis are described. Also disclosed are methods for increasing the growth of microorganisms or eukaryotic cells and methods for reducing the accumulation of undesirable metabolic products in the growth medium of microorganisms or cells.

公开(公告)号：WO1989011857A1

公开(公告)日：1989-12-14

申请号：PCT/US1989002164

申请日：1989-05-18

Applicant: UNIVERSITY OF FLORIDA

Inventor： UNIVERSITY OF FLORIDA ,  GOLDBERG, Eugene, P. ,  YAACOBI, Yoseph

IPC: A61K31/79

CPC classification number: A61L31/10 ,  A61K31/727 ,  A61K31/728 ,  A61K31/79 ,  A61L17/145 ,  C08L39/06 ,  C08L5/08 ,  C08L1/28 ,  A61K31/74

Abstract: An improved method and composition for preventing adhesions during surgery. Tissue surfaces and surgical articles involved in the surgery are coated with a solution of a hydrophilic, polymeric material prior to manipulation of the tissue during surgery. The composition comprises a solution of a polymeric material having a molecular weight of about 500,000 or above having a concentration of from about 0.01 to about 15 %, by weight.

Abstract translation: 用于预防手术中粘连的改进方法和组合物。 在手术期间在组织操作之前，将包括在手术中的组织表面和手术制品涂覆在亲水性聚合物材料的溶液中。 组合物包含分子量为约500,000或更高的聚合物材料的溶液，其浓度为约0.01至约15重量％。

公开(公告)号：WO1989005575A1

公开(公告)日：1989-06-29

申请号：PCT/US1988003934

申请日：1988-11-15

Applicant: UNIVERSITY OF FLORIDA

Inventor： UNIVERSITY OF FLORIDA ,  GRAY, Dennis, J. ,  CONGER, Bob, V.

IPC: A01G07/00

CPC classification number: A01C1/00 ,  A01H4/006

Abstract: A method of producing synthetic seeds by inducing growth quiescence in plant somatic embryos by maintaining the embryos in an atmosphere having a relative humidity of 30-85 % or in an osmotically active environment having a moisture content of 30-85 % for a period of time sufficient to reduce the moisture content of the embryos to from 85-65 % to 4-15 % and for the embryos to cease growth.

Abstract translation: 通过在相对湿度为30-85％的气氛中或在水分含量为30-85％的渗透活性环境中保持胚胎一段时间来诱导植物体细胞胚中的生长静止来生产合成种子的方法 足以将胚胎的水分含量从85-65％降低到4-15％，并使胚胎停止生长。

公开(公告)号：WO1985003937A1

公开(公告)日：1985-09-12

申请号：PCT/US1985000236

申请日：1985-02-15

Applicant: UNIVERSITY OF FLORIDA ,  BODOR, Nicholas, S.

Inventor： UNIVERSITY OF FLORIDA

IPC: C07D213/82

CPC classification number: C07D213/82 ,  A61K47/559 ,  C07D211/90

Abstract: The subject compounds, which are adapted for the site-specific/sustained delivery of centrally acting drug species to the brain, are compounds of the formula (I), and the non-toxic pharmaceutically acceptable salts thereof, wherein D is the residue of a centrally acting primary, secondary or tertiary amine and -N is an unsubstituted or substituted dihydropyridyl, dihydroquinolyl or dihydroisoquinolyl radical. The corresponding ionic pyridinium, quinolinium and isoquinolinium salts D-N+ X , wherein X is the anion of a non-toxic pharmaceutically acceptable acid, are also disclosed.

Abstract translation: 适于中枢作用的药物物种的位点特异性/持续递送至脑的主题化合物是式（I）的化合物及其无毒的药学上可接受的盐，其中D是 中心作用的伯，仲或叔胺和-N是未取代或取代的二氢吡啶基，二氢喹啉基或二氢异喹啉基。 还公开了相应的离子型吡啶鎓，喹啉鎓和异喹啉鎓D-N + X - ，其中X - 是无毒的药学上可接受的酸的阴离子。

公开(公告)号：WO1998016110A1

公开(公告)日：1998-04-23

申请号：PCT/US1997018343

申请日：1997-10-10

Applicant: UNIVERSITY OF FLORIDA

Inventor： UNIVERSITY OF FLORIDA ,  MARTIN, Frank, N.

IPC: A01N63/04

CPC classification number: C12R1/645 ,  A01N63/04 ,  C07K14/375

Abstract: Described are non-phytopathogenic Pythium oligandrum isolates having activity to control phytopathogenic Pythium spp. or control damping-off of a plant, by applying an effective amount of the non-phytopathogenic isolates to a plant or its situs. The isolates can be applicable to vegetable crops utilizing transplant systems. Also described are methods of using the isolates and novel genetic sequences identified from the isolates which can be useful in identification procedures.

Abstract translation: 描述了具有控制植物病原性腐霉属（Pythium spp）的活性的非植物致病性腐霉菌（Pythium oligandrum）菌株。 或控制植物的阻尼，通过将有效量的非植物病原性分离物施用于植物或其部位。 分离株可适用于利用移植系统的蔬菜作物。 还描述了使用从分离物鉴定的分离物和新型遗传序列的方法，其可用于鉴定程序。