Abstract:
A multi-channel fluorescence measuring optical system and a multi-channel fluorescence sample analyzer using the optical system are provided. The multi-channel fluorescence measuring optical system, which irradiates light onto a plurality of sample channels and detecting fluorescence radiated from samples, includes: a light source (60a-d); an integrator (70) for giving the light irradiated from the light source a uniform intensity distribution; a sample holder (80) having a plurality of sample channels on which the samples (m) are mounted, wherein the samples are exited by the light emitted from the integrator; and a beam splitter (75) between the integrator and the sample holder for dividing the incident light in a predetermined ratio. Since the light intensities of fluorescence images are detected using optical fiber bundles (85a-d) and photodiodes (89a-d), the manufacturing cost can be greatly reduced, and the optical system can be miniaturized.
Abstract:
A photometric reading device comprises a plurality of reading elements (30), each comprising a light emitting diode and a corresponding photodiode on opposing sides of a sample pathway along which a sample microplate (l0) can travel. The microplate (l0) includes rows of sample wells arranged transverse to the line of relative motion of the microplate (l0) and the reading elements (30). The reading elements (30) are arranged such that, during continuous relative motion of the reading elements (30) and the microplate (l0), the reading elements (30) come into registration sequentially with the wells in the first row of wells in the microplate (l0), then with the wells in the second row of wells, and so on.
Abstract:
57 Endotoxin contents in samples can be determined qualitatively or quantitatively, singly or in parallel, with high precision in a short time by a process comprising applying a light to each sample solution, measuring an initial transmitted light amount l o and a transmitted light amount at a time t, I(t), to give a ratio R(t) = l(t)/l o , and judging a gelation point by a threshold value of R(t), or further obtaining a gelation time from the gelation point. An apparatus used therefore is also disclosed.
Abstract:
PROBLEM TO BE SOLVED: To provide a device for a photometric test of a sample which is hardly failed and capable of avoiding a variation in accuracy among individual detection units. SOLUTION: The device includes at least: sample holder equipment (11) having a holding means (15) for holding at least two sample containers; measurement equipment; and movable equipment (14) where the sample holder equipment (11) is fixed, and the measurement equipment is arranged on the movable equipment (14) and can be displaced by the movable equipment. COPYRIGHT: (C)2011,JPO&INPIT
Abstract:
PROBLEM TO BE SOLVED: To provide an optical system for multi-channel fluorometry. SOLUTION: This optical system for the multi-channel fluorometry for emitting light to a plurality of sample channels to detect fluorescence emitted from samples includes a light source 10; an integrator 20 for bringing the light emitted from the light source into light having a uniform intensity distribution; a sample holder 30 provided with the plurality of sample channels for mounting the samples fluorescence-reacting with the light emitted from the integrator; and a beam splitter 33 arranged between the integrator and the sample holder to separate incident light at a prescribed ratio. COPYRIGHT: (C)2006,JPO&NCIPI
Abstract:
A system for measuring optical signal detector performance includes an optical signal detector comprising a first detection channel having a first light source and a first sensor. The first detection channel is configured to emit and focus light generated by the first light source at a first detection zone, and to receive and focus light on the first sensor. The system also includes a controller operatively coupled to the optical signal detector and configured to determine an operational performance status of the optical signal detector based on at least one of (i) a first measured characteristic of light focused on the sensor while a first non-fluorescent surface portion is in the first detection zone and (ii) a second measured characteristic of light focused on the sensor while a void is in the first detection zone. The optical signal detector can be a fluorometer.