公开(公告)号：US20150164468A1

公开(公告)日：2015-06-18

申请号：US14538039

申请日：2014-11-11

Applicant: INSTITUTE FOR BASIC SCIENCE

Inventor： CHI YOUNG AHN ,  KI WAN JEON ,  SUNG HO KANG

IPC: A61B8/08 ,  G06T17/00 ,  A61B8/06

CPC classification number: A61B8/0883 ,  A61B8/06 ,  A61B8/488 ,  A61B8/5207 ,  A61B8/5223 ,  A61B8/5253 ,  G01S15/8984 ,  G01S15/8993 ,  G01S15/8995 ,  G06T7/269 ,  G06T7/55 ,  G06T17/00 ,  G06T2207/10132 ,  G06T2207/30048 ,  G06T2207/30104

Abstract: An apparatus and method for processing an echocardiogram using the Navier-Stokes equation is provided. The apparatus includes an ultrasonic sensor that transmits ultrasonic waves to the heart in three different directions and receives echoes thereof; an image processor that constructs first to third echocardiograms captured from the three different directions, respectively, based on the received echoes of the ultrasonic waves; a three-dimensional model construction unit that constructs a three-dimensional model of a left ventricle of the heart based on the first to third echocardiograms; and a blood flow vector calculation unit that calculates blood flow vectors within the left ventricle by applying the three-dimensional model of the left ventricle to boundary conditions in the Navier-Stokes equation. In echocardiogram processing, vector components of the blood flow within the left ventricle are calculated using the Navier-Stokes equation, whereby the vector components of the blood flow can be more accurately calculated.

Abstract translation: 提供了一种使用Navier-Stokes方程处理超声心动图的装置和方法。 该装置包括：超声波传感器，其以三个不同的方向向心脏发送超声波并接收其回波; 基于所接收到的超声波的回波，分别构建从三个不同方向捕获的第一到第三超声心动图的图像处理器; 基于第一至第三超声心动图构建心脏左心室的三维模型的三维模型构建单元; 以及血流矢量计算单元，其通过将所述左心室的三维模型应用于Navier-Stokes方程中的边界条件来计算所述左心室内的血流矢量。 在超声心动图处理中，使用Navier-Stokes方程计算左心室内血流量的矢量分量，从而可以更精确地计算血流的矢量分量。

公开(公告)号：US12241166B2

公开(公告)日：2025-03-04

申请号：US17588597

申请日：2022-01-31

Applicant: RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY ,  INSTITUTE FOR BASIC SCIENCE

Inventor： Hyoyoung Lee ,  Jadhav Amol

IPC: C25B11/053 ,  C25B1/04

Abstract: The present application relates to an electrode catalyst for water electrolysis including a first transition metal foam, a metal layered double hydroxide (LDH)/metal oxide mixed layer which contains a second transition metal and a third transition metal that are formed on the surface of the first transition metal foam, and fourth transition metal oxyhydroxide nanoparticles formed on the surface of the mixed layer, in which the mixed layer surface contains the metal layered double hydroxide.

公开(公告)号：US12235166B2

公开(公告)日：2025-02-25

申请号：US17606279

申请日：2019-10-17

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION ,  INSTITUTE FOR BASIC SCIENCE

Inventor： Je Geun Park ,  Ha Leem Kim ,  Matthew John Coak

IPC: G01K1/14 ,  G01K1/02 ,  G01K7/34 ,  G01K13/00

Abstract: Provided is a probe system for low-temperature high-precision heat transport measurement, the probe system including a sample loader where a sample is loaded. In the probe system for low-temperature high-precision heat transport measurement, the sample loader includes a first frame including a sample loading space, and a second frame including an open end coupled to the first frame to accommodate the sample loading space.

公开(公告)号：US12188120B2

公开(公告)日：2025-01-07

申请号：US18047970

申请日：2022-10-19

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION ,  INSTITUTE FOR BASIC SCIENCE

Inventor： Jungwon Park ,  Jihoon Kim

IPC: C23C16/30 ,  C23C16/02 ,  C23C16/458 ,  C23C16/46

Abstract: A method of forming a compound structure according to embodiments of the present disclosure comprises loading a metal precursor on a substrate, providing a chalcogen precursor to the substrate, and reacting the chalcogen precursor with the metal precursor. The metal precursor comprises transition metal nanoparticles. The compound structure has a 2-dimensional structure.

公开(公告)号：US12168684B2

公开(公告)日：2024-12-17

申请号：US17468590

申请日：2021-09-07

Applicant: INSTITUTE FOR BASIC SCIENCE

Inventor： Won Do Heo ,  Yun Ju Lee ,  Daseuli Yu ,  Byung Ouk Park

IPC: C07K16/00 ,  C07K14/00 ,  C07K16/14 ,  C07K16/18

Abstract: The present invention relates to the preparation of an antibody analogue capable of being activated reversibly, and uses thereof, and provides a fusion protein comprising an inactive first fragment of an antibody analogue is fused to a stimulus-induced dimerization protein.

公开(公告)号：US20240350471A1

公开(公告)日：2024-10-24

申请号：US18684841

申请日：2021-08-20

Applicant: DANKOOK UNIVERSITY CHEONAN CAMPUS INDUSTRY ACADEMIC COOPERATION FOUNDATION ,  INSTITUTE FOR BASIC SCIENCE

Inventor： Bo-Eun Yoon ,  C. Justin Lee ,  Yoo Sung Kim ,  Moonsun Sa

IPC: A61K31/445 ,  A61K9/00 ,  A61P25/20 ,  C12Q1/6883 ,  G01N33/68

CPC classification number: A61K31/445 ,  A61K9/0056 ,  A61P25/20 ,  C12Q1/6883 ,  G01N33/6896 ,  C12Q2600/158 ,  G01N2800/305

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating attention deficit/hyperactivity disorder (ADHD), including SNAP5114 as an active ingredient. A Git1 gene-deficient hetero (+/−) mouse, confirmed to have increased amount of GABA in the brain striatum that controls hyperactivity, can be used as an animal model of ADHD, and by confirming that hyperactivity is ameliorated by administering SNAP5114 to the Git1 gene-deficient hetero (+/−) mouse, SNAP5114 is provided as a therapeutic agent for ADHD.

公开(公告)号：US20240272045A1

公开(公告)日：2024-08-15

申请号：US18566705

申请日：2022-06-03

Applicant: INSTITUTE FOR BASIC SCIENCE ,  UNIST(ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY)

Inventor： Yoon-Kyoung CHO ,  Vijaya SUNKARA

IPC: G01N1/34 ,  B01D15/38 ,  B01D21/01 ,  B01D21/26 ,  C12N5/09 ,  C12N15/10

CPC classification number: G01N1/34 ,  B01D15/3809 ,  B01D15/3828 ,  B01D21/01 ,  B01D21/262 ,  C12N5/0693 ,  C12N15/101 ,  C12N2509/10

Abstract: The present invention relates to a method and kit for isolating an extracellular vesicle (EV) from a biological sample using fractional precipitation. According to the method and kit, rapid isolation is possible, and an EV can be effectively isolated from various types of biological samples regardless of the sample sources. Unlike a method for isolating an EV on the basis of an existing precipitation method, the present invention can easily remove a salt by washing, and, thus, has the benefit of being able to isolate a highly pure EV with a high yield rate and can be applied to both small-scale EV isolation in research and diagnostic fields and large-scale EV isolation for industrial applications.

公开(公告)号：US20240263262A1

公开(公告)日：2024-08-08

申请号：US18640113

申请日：2024-04-19

Applicant: INSTITUTE FOR BASIC SCIENCE ,  UNIST(ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY)

Inventor： Ruoff RODNEY S. ,  Sunghwan JIN

IPC: C21D1/40 ,  C21D9/46 ,  C22F1/00 ,  C22F1/14 ,  C30B35/00

CPC classification number: C21D1/40 ,  C21D9/46 ,  C22F1/002 ,  C22F1/14 ,  C30B35/00

Abstract: The present invention relates to a method for manufacturing a monocrystalline metal foil and a monocrystalline metal foil manufactured thereby, the method comprising the steps of: fixing each of the ends of a polycrystalline metal foil to electrodes; and heat-treating the fixed polycrystalline metal foil to manufacture a monocrystalline metal foil.

公开(公告)号：US11981780B2

公开(公告)日：2024-05-14

申请号：US16606143

申请日：2018-04-18

Applicant: INSTITUTE FOR BASIC SCIENCE ,  POSTECH ACADEMY-INDUSTRY FOUNDATION

Inventor： Won Jong Kim ,  Junghong Park

IPC: C08J3/075 ,  C08J3/24 ,  F01N11/00 ,  G02C7/04

CPC classification number: C08J3/075 ,  C08J3/24 ,  F01N11/00 ,  C08J2387/00 ,  F01N2570/12 ,  G02C7/04

Abstract: The present invention relates to a polymeric gel comprising crosslink points, which are dissociated in response to nitrogen monoxide, and to a method for preparing a hydrogel, the method comprising the steps of: a) polymerizing a mixture of monomers comprising a monofunctional hydrophilic monomer and a monomer comprising a plurality of functional groups comprising an o-phenylenediamine residue; and b) separating a hydrogel formed by the polymerization.

公开(公告)号：US20240083959A1

公开(公告)日：2024-03-14

申请号：US18273080

申请日：2022-01-24

Applicant: INSTITUTE FOR BASIC SCIENCE ,  INHA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION ,  KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Ho Min KIM ,  Do-Kyun KIM ,  Ji-Kan RYU

IPC: C07K14/47

CPC classification number: C07K14/473 ,  A61K38/00

Abstract: The present invention relates to a deglycosylated LRG1 glycoprotein and a LRG1 glycoprotein variant, and a use thereof. The deglycosylated LRG1 glycoprotein and LRG1 glycoprotein variant of the present invention exhibit effects of angiogenesis, nerve growth and nerve regeneration that are superior to those of conventional LRG1 glycoproteins, and thus a composition containing thereof is effective in preventing and treating vascular erectile dysfunction, ischemic heart/brain/peripheral vascular diseases, diabetic vascular complications, neurogenic erectile dysfunction, diabetic neurologic complications, post-operative/post-traumatic peripheral nerve damage, ischemic diseases including neurodegenerative diseases, peripheral nerve diseases, erectile dysfunction and/or neurodegenerative diseases.