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公开(公告)号：DK120714B
公开(公告)日：1971-07-05
申请号：DK405569
申请日：1969-07-25
Applicant: MICROMEDIC SYSTEMS INC
Inventor： SANZ M , REVILLET G
Abstract: 1277762 Blood sampling apparatus MICROMEDIC SYSTEMS Inc 16 July 1969 [26 July 1968] 35716/69 Heading A5R Apparatus is provided for obtaining a blood sample from a patient's finger using a collector device 15, Fig. 11, of the type disclosed in Specification 1277761 having a tube 32 and a resilient funnel member 35 with incisor lancets 38a, 38b, the apparatus having a mounting 12, Fig. 2, having a through passage 12c in which the collector 15 is supported, a striker mechanism having a releasable member 17 adapted to strike a lower end of tube 32 to force lancets 38a, b into a patients' finger placed over funnel 35, a finger holder 8, and means for periodically varying the intensity of clamping of said holder. Holder 8 is pivoted at 7 and has a pin 8c which during pivoting of the holder engages member 17, to pivot the latter against springs 14, and then releases member 17 which consequently strikes tube 32. Holder 8 is retained in its clamping position by engagement of teeth 8f with a grooved rod 29 on a lever 25, the degree of clamping being varied by a massaging-type movement of a finger support 6 on a lever 19 driven through an eccentric by a motor. The first drops of impure blood are absorbed by a pad 40 in funnel 35, the remaining sample passing into tube 32 until a light beam, passing through tube 32 from a source to a photo cell in mounting 12, is interrupted, whereupon a solenoid coil 23 is energised and attracts an armature 22 on a lever 21, the end of which lever thus becomes engageable with a projection 19a on lever 19 to move levers 21 and 25 thus releasing holder 8 which is acted on by a return spring 11, the actuation of the solenoid also stopping the motor. Holder 8 may alternatively be released and the motor stopped via a push button 4. In an alternative embodiment, Figs. 13-16 (not shown) the finger is clamped and massaged between a fixed swell (45) on a casing (42) and a sponge pad (46) secured to a stirrup (41) pivoted on an eccentrically driven pin (43).
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公开(公告)号：ZA701872B
公开(公告)日：1971-05-27
申请号：ZA701872
申请日：1970-03-19
Applicant: MICROMEDIC SYSTEMS INC
Inventor： SANZ M
Abstract: 1310246 Determination of coagulation time of blood samples MICROMEDIC SYSTEMS Inc 19 March 1972 [19 March 1969] 13252/70 Heading B1X [Also in Divisions G1 and G3] Apparatus for measuring the coagulation time of a blood sample in a container 1, 2 equipped with a stirrer and supported on heatable turntable 52 comprises (Fig. 1) electric motor M, a rotatable drive assembly comprising two coaxial drive shafts 38, 31, shaft 38 being connectable to the stirrer and shaft 31 being drivable by the motor through bevel gears 29, 30 shaft 38 (Fig. 4) being capable of limited rotational movement relative to shaft 31 between first and second angular positions, friction means which may comprise spring 36 with its lower end engaging gear 30 when shaft 38 has been manually lowered to lower the stirrer into the container, the friction means holding the shaft 38 in its first position until the sample coagulates, the circuit to the motor M including a switch the movable part of which may be spring 36, the disengagement of the end of the spring from gear 30 when coagulation of the sample increases the drag on shaft 38 and moves it to its second angular position operating automatically to break the circuit and stop motor M, and means for example counter 19 for measuring the time of operation of the motor. In the apparatus shown, shaft 38 is lowered to engage the stirrer in the sample container by manual operation of rod 23. Shaft 38 carries key 37 to move in a slot (35) in the outer shaft 31 until it bears against the lower end of spring 36 forcing it into contact with gear 30 and so starting the motor. Containers 1, 2 may be prepacked with reagents for use in the test as in Specification 1310245.
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公开(公告)号：CH499033A
公开(公告)日：1970-11-15
申请号：CH1239868
申请日：1968-08-16
Applicant: MICROMEDIC SYSTEMS INC
Inventor： MANUEL SANZ , RENE WEBER
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公开(公告)号：DE2726323C2
公开(公告)日：1987-05-07
申请号：DE2726323
申请日：1977-06-10
IPC: C12M1/00 , B01L7/00 , C12M1/32 , C12M1/34 , C12M1/38 , C12Q1/10 , G01N35/02 , G01N35/04 , C12M1/36 , C12M3/00
Abstract: An incubation apparatus for use in automated biochemical analyzer system which comprises a block of thermoconductive material having rows of wells for the reception of sample carriers to be incubated with temperature control attached to the block; the block resting with well openings facing downward upon a pair of insulating plates so arranged that by movement of one of the plates, a row of wells is exposed so as to allow a number of sample carriers, equivalent in number to the number of wells in a row, to be loaded into that row of wells, the sample carriers being in alignment with and directly below the row of wells; and a means for lifting the sample carriers up into the wells or lowering sample carriers down out of the wells.
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公开(公告)号：NL178486C
公开(公告)日：1986-04-01
申请号：NL7612395
申请日：1976-11-08
Applicant: MICROMEDIC SYSTEMS INC
Abstract: A guide rail or track system for guiding test tube holders or racks from one station to another, e.g., in a mono-channel analyzer, for presenting test tubes in such holders in sequence to one or more servicing operations at a plurality of stations. The rail system may comprise a main linear guide rail along which a holder having a row of test tubes supported therein is adapted to be moved longitudinally stepwise to present each test tube in the holder in sequence to a given station, or a given position therein, where an operation is to be carried out with respect to each test tube as it is presented in the station. Arranged at right angles to the main rail, one or more branch rails leading to or from other service stations are provided at spaced intervals and the main rail at each juncture or intersection of these rails is constructed to allow a lateral shift of the holder (also specially constructed to allow such shift) to or from the main rail respectively from or to the branch rail along which the holder moves laterally, i.e., the lengthwise dimension of the holder extends across the branch rail at right angles to it as the test tube holder moves along the branch rail, which may terminate at a junction or intersection with another or subsidiary rail or guideway along which the holder moves longitudinally in a direction parallel to the main rail. Means is provided for moving the holder along the main rail and means is provided at the junction of a branch rail with an intersecting rail such as the main rail, for laterally shifting the holder from the junction.
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Patent Agency Ranking
公开(公告)号：NL169691C
公开(公告)日：1982-08-16
申请号：NL6905076
申请日：1969-04-01
Applicant: MICROMEDIC SYSTEMS INC
Abstract: Apparatus for repeatedly metering and dispensing, by means of a piston pump, predetermined quantities of liquid via a switching valve to which are connected inlet and outlet conduits for the liquid. The pump and the valve are actuated in timed relation by a drive mechanism powered by an electric motor which is controlled by selectively operable means that automatically cut off the motor supply once the piston has completed a stroke. There are also provided means for varying the length of the piston stroke to adjust the volume of said quantities and means for displaying to the outside a number indicative of this volume.
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公开(公告)号：CH615019A5
公开(公告)日：1979-12-28
申请号：CH734977
申请日：1977-06-15
Applicant: MICROMEDIC SYSTEMS INC
Inventor： JOHNSON EDGAR GREY , MCGILL HOWARD LAWRENCE
IPC: C12M1/00 , B01L7/00 , C12M1/32 , C12M1/34 , C12M1/38 , C12Q1/10 , G01N35/02 , G01N35/04 , G01N1/28
Abstract: An incubation apparatus for use in automated biochemical analyzer system which comprises a block of thermoconductive material having rows of wells for the reception of sample carriers to be incubated with temperature control attached to the block; the block resting with well openings facing downward upon a pair of insulating plates so arranged that by movement of one of the plates, a row of wells is exposed so as to allow a number of sample carriers, equivalent in number to the number of wells in a row, to be loaded into that row of wells, the sample carriers being in alignment with and directly below the row of wells; and a means for lifting the sample carriers up into the wells or lowering sample carriers down out of the wells.
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108.发明专利
公开(公告)号：CA1021960A
公开(公告)日：1977-12-06
申请号：CA213247
申请日：1974-11-07
Applicant: MICROMEDIC SYSTEMS INC
Inventor： JOHNSON EDGAR G JR , LAWSON CHARLES V , STONECYPHER THOMAS E
Abstract: 1487775 Absorbance change measurement MICROMEDIC SYSTEMS Inc 23 Dec 1974 [19 Feb 1974] 55541/74 Heading G1A The change in absorbance per unit time of sample is measured by periodically developing digital signals, each comprising a pulse train having a length proportional to the logarithm of the ratio of the intensities of radiation passed through the sample and a standard, respectively, and utilizing counting apparatus to compare the numbers of pulses generated in two consecutive time intervals forming two sequential digital signals. Photo-electric absorption measurement system, Fig. 1. A wide band optical source 104 illuminates a mono-chromator section 200, including inlet and outlet apertures 215, 216 and a diffraction grating 201. The selected wavelength is displayed on monitor 800. When red, infrared or ultraviolet light is used, an extra filter appropriate to the radiation is introduced by slide 205, so as to prevent stray or second order diffraction light reaching the sample. The sample and reference cuvette section 300 may be supplied intermittently or continuously with fluids. The optical beam is switched between illumination of the sample and the reference by a pair of quartz, plastics or glass cross-mounted elongated prismatic elements 401, 402. A synchronization 600 coupled to sense which of the sample and reference is being illuminated controls delivery of the signal developed by photo-multiplier 501 sensing transmitted beam to the evaluation circuit 700. A prism 52 directs the alternate beams on to the detector 501. Detector and counting circuit, Fig. 2. A clock 806 periodically stimulates generation of an exponentially decaying signal from circuit 808. Applied to inputs 810, 812 are voltages representing the detector output for the reference and sample transmissions respectively. As the exponential signal falls below these negative voltage levels, as sensed by comparators 802, 804, a constant height pulse of duration logarithmically proportional to the difference between the voltages is produced from Exclusive -OR gate 818. This is converted into a digital signal i.e. a pulse train by oscillator 902 and gate 904. Depending on which is greater of the sample and reference voltages, up or down counting is initiated in counters 912, 914. Except for the first timing interval, the counters operate as follows:- counter 912 counts the currently supplied pulses in a digital signal and at the end of the interval transfers this number to counter 914, after which it is cleared; counter 914 counts in the opposite direction to counter 912 and so effectively subtracts the current member from the number for the previous digital signal, timing interval; thereby at the end of the timing interval, having accumulated therein an absorbance difference representative number. If there is a difference, this is printed out at 916. Other parts of Fig. 2 circuit are for scaling so that the printer provides the required units. Variations on the repetition rate and length of timing intervals are possible. Counters 912, 914 may be arranged to subtract alternately, the other counter storing the number for the current digital signal.
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公开(公告)号：FR2261522B1
公开(公告)日：1977-11-25
申请号：FR7500539
申请日：1975-01-09
Applicant: MICROMEDIC SYSTEMS INC
Abstract: 1487775 Absorbance change measurement MICROMEDIC SYSTEMS Inc 23 Dec 1974 [19 Feb 1974] 55541/74 Heading G1A The change in absorbance per unit time of sample is measured by periodically developing digital signals, each comprising a pulse train having a length proportional to the logarithm of the ratio of the intensities of radiation passed through the sample and a standard, respectively, and utilizing counting apparatus to compare the numbers of pulses generated in two consecutive time intervals forming two sequential digital signals. Photo-electric absorption measurement system, Fig. 1. A wide band optical source 104 illuminates a mono-chromator section 200, including inlet and outlet apertures 215, 216 and a diffraction grating 201. The selected wavelength is displayed on monitor 800. When red, infrared or ultraviolet light is used, an extra filter appropriate to the radiation is introduced by slide 205, so as to prevent stray or second order diffraction light reaching the sample. The sample and reference cuvette section 300 may be supplied intermittently or continuously with fluids. The optical beam is switched between illumination of the sample and the reference by a pair of quartz, plastics or glass cross-mounted elongated prismatic elements 401, 402. A synchronization 600 coupled to sense which of the sample and reference is being illuminated controls delivery of the signal developed by photo-multiplier 501 sensing transmitted beam to the evaluation circuit 700. A prism 52 directs the alternate beams on to the detector 501. Detector and counting circuit, Fig. 2. A clock 806 periodically stimulates generation of an exponentially decaying signal from circuit 808. Applied to inputs 810, 812 are voltages representing the detector output for the reference and sample transmissions respectively. As the exponential signal falls below these negative voltage levels, as sensed by comparators 802, 804, a constant height pulse of duration logarithmically proportional to the difference between the voltages is produced from Exclusive -OR gate 818. This is converted into a digital signal i.e. a pulse train by oscillator 902 and gate 904. Depending on which is greater of the sample and reference voltages, up or down counting is initiated in counters 912, 914. Except for the first timing interval, the counters operate as follows:- counter 912 counts the currently supplied pulses in a digital signal and at the end of the interval transfers this number to counter 914, after which it is cleared; counter 914 counts in the opposite direction to counter 912 and so effectively subtracts the current member from the number for the previous digital signal, timing interval; thereby at the end of the timing interval, having accumulated therein an absorbance difference representative number. If there is a difference, this is printed out at 916. Other parts of Fig. 2 circuit are for scaling so that the printer provides the required units. Variations on the repetition rate and length of timing intervals are possible. Counters 912, 914 may be arranged to subtract alternately, the other counter storing the number for the current digital signal.
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公开(公告)号：GB1407247A
公开(公告)日：1975-09-24
申请号：GB3862772
申请日：1972-08-18
Applicant: MICROMEDIC SYSTEMS INC
Inventor： SANZ MC , REVILLET G
Abstract: 1407247 Cuvette MICROMEDIC SYSTEMS Inc 18 Aug 1972 [27 Aug 1971] 38627/72 Heading G2J A cuvette is made up of plates 2a, 2b sandwiching a further plate or plates defining a passage 4 through which a liquid to be optically investigated is passed. Light for this purpose is projected along line O-O. Further plates can be added to define a parallel passage.
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