公开(公告)号：WO2012051300A2

公开(公告)日：2012-04-19

申请号：PCT/US2011/055966

申请日：2011-10-12

Applicant: WORCESTER POLYTECHNIC INSTITUTE ,  CHON, Ki, H. ,  SELVARAJ, Nandakumar

Inventor： CHON, Ki, H. ,  SELVARAJ, Nandakumar

IPC: A61B5/0285 ,  A61B5/02 ,  G06F19/00

CPC classification number: G06F19/34 ,  A61B5/02416 ,  A61B5/7203 ,  A61B5/7207 ,  A61B5/721 ,  A61B5/7214 ,  A61B5/7253 ,  G06F19/00 ,  G06K9/00563

Abstract: Methods and systems for quantitatively detecting the presence of artifacts in physiological measurement data and for determining usable data among those that have been designated to be corrupted with artifacts are presented.

Abstract translation: 提出了用于定量检测生理测量数据中伪像的存在以及用于确定已被指定为被损坏的伪像之间的可用数据的方法和系统。

公开(公告)号：WO2011152988A1

公开(公告)日：2011-12-08

申请号：PCT/US2011/036735

申请日：2011-05-17

Applicant: RAYTHEON COMPANY ,  WORCESTER POLYTECHNIC INSTITUTE ,  PUZELLA, Angelo, M. ,  MAKAROV, Sergey ,  MORRISON, Patrick

Inventor： PUZELLA, Angelo, M. ,  MAKAROV, Sergey ,  MORRISON, Patrick

IPC: H01P1/161 ,  H01P5/10 ,  H01Q9/28 ,  H01Q21/06 ,  H01Q21/26

CPC classification number: H01P5/10 ,  H01Q9/28 ,  H01Q21/062 ,  H01Q21/26

Abstract: An antenna element (10) and a quad- line balun column (12) are described. The antenna includes a plurality of droopy bowtie antenna elements (10) disposed on dielectric block (16) and a feed point. The quad-line balun column (12) includes a central member having dielectric slabs symmetrically disposed on external surfaces thereof. At least one end of the balun is provided having a shape such that conductors on the dielectric slabs of the balun can be coupled to the droopy bowtie antenna elements. The quad- line balun column is mechanically stable facilitates the assembly, and provides coincident phase centres for orthogonal dipoles. Thze antenna element provides broad bandwidth, high cross -polarization isolation characteristic and is mechanically stable.

Abstract translation: 描述了天线元件（10）和四线平衡 - 不平衡转换器（12）。 天线包括设置在介电块（16）和馈电点上的多个下降弓形天线元件（10）。 四行平衡 - 不平衡转换柱（12）包括具有对称地设置在其外表面上的电介质板的中心构件。 平衡 - 不平衡转换器的至少一端被提供有使得平衡 - 不平衡转换器的电介质板上的导体可以耦合到下垂天线元件的形状。 四线平衡 - 不平衡转换柱机械稳定便于组装，并为正交偶极子提供重合的相位中心。 Thze天线元件提供宽带宽，高交叉极化隔离特性，并且机械稳定。

公开(公告)号：WO2011146439A2

公开(公告)日：2011-11-24

申请号：PCT/US2011/036753

申请日：2011-05-17

Applicant: WORCESTER POLYTECHNIC INSTITUTE ,  PRUSTY RAO, Reeta

Inventor： PRUSTY RAO, Reeta

CPC classification number: G01N33/56961 ,  C12Q1/18 ,  G01N33/6872 ,  G01N2333/37 ,  G01N2500/04 ,  G01N2500/10

Abstract: The present invention relates to methods of screening for antifungal agents by identifying agents that bind to or otherwise inhibit indole-3 -acetic acid (IAA) or that bind to or otherwise inhibit the expression or activity of a protein within the Yap family or a gene encoding a protein within the Yap family.

Abstract translation: 本发明涉及通过鉴定结合或以其它方式抑制吲哚-3-乙酸（IAA）或结合或以其它方式抑制Yap家族或基因内的蛋白质的表达或活性的试剂筛选抗真菌剂的方法 编码Yap家族内的蛋白质。

公开(公告)号：WO2011133974A2

公开(公告)日：2011-10-27

申请号：PCT/US2011/033785

申请日：2011-04-25

Applicant: WORCESTER POLYTECHNIC INSTITUTE ,  CYGANSKI, David ,  DUCKWORTH, R. James

Inventor： CYGANSKI, David ,  DUCKWORTH, R. James

IPC: G01S5/02

CPC classification number: G01S3/146 ,  G01S3/28 ,  G01S5/0205 ,  G01S11/06 ,  G08B21/0263 ,  H01Q21/24 ,  H01Q21/28

Abstract: A method for locating a transmitter using a receiver which include, but are not limited to the steps of transmitting a plurality of distinctive and orthogonally polarized signals from a transmitter; receiving the transmitted signals at a pair of separated antennas; demodulating the distinctive orthogonal signals received at each of the pair of separated antennas; and determining a direction to the transmitter from the signals received at the pair of antennas. The system for determining the location of a transmitter using a receiver includes, but is not limited to, having a transmitter adapted for orthogonally transmitting a plurality of distinctive signals; a receiver having a pair of separated antennas for receiving the orthogonally transmitted signals; separate demodulators in the receiver for each antenna of the pair of separated antennas for demodulating the distinctive signals; and signal processing circuitry in the receiver adapted for using the demodulated distinctive signals for determining a direction to the transmitter.

Abstract translation: 一种用于使用接收机定位发射机的方法，包括但不限于从发射机发送多个不同的和正交极化信号的步骤; 在一对分离的天线处接收发送的信号; 解调在所述一对分离天线中的每一个处接收的所述不同的正交信号; 以及根据在所述一对天线处接收的信号确定到所述发射机的方向。 用于使用接收机确定发射机的位置的系统包括但不限于具有适于正交发射多个不同信号的发射机; 具有一对分离天线的接收机，用于接收正交发射的信号; 用于解调不同信号的分离天线对中的每个天线的接收机中的单独的解调器; 以及接收器中的信号处理电路，其适于使用解调的特征信号来确定发射机的方向。

公开(公告)号：WO2011112601A2

公开(公告)日：2011-09-15

申请号：PCT/US2011/027579

申请日：2011-03-08

Applicant: WORCESTER POLYTECHNIC INSTITUTE ,  LAMBERT, Christopher, R. ,  MCGIMPSEY, W., Grant ,  PAGE, Raymond, L ,  DOMINKO, Tanya

Inventor： LAMBERT, Christopher, R. ,  MCGIMPSEY, W., Grant ,  PAGE, Raymond, L ,  DOMINKO, Tanya

IPC: C12M3/02 ,  C12M3/06 ,  C12M1/42 ,  C12M1/12 ,  A61L27/38

CPC classification number: C12N11/14 ,  C12M21/02 ,  C12M21/08 ,  C12M25/16 ,  C12M35/06 ,  C12N1/12 ,  C12N5/0062 ,  C12N13/00 ,  C12N2513/00 ,  C12N2521/00 ,  C12N2529/00 ,  C12N2531/00

Abstract: The invention provides methods for rapid, continuous generation of cells and cell products using magnetically stabilized three-dimensional tissue culture. The invention also pertains to a continuous flow self-regulating closed system bioreactor system for magnetically stabilized three-dimensional tissue culture. The methods described here do not use traditional solid scaffolding for cell culture.

Abstract translation: 本发明提供了使用磁稳定的三维组织培养物快速，连续地产生细胞和细胞产物的方法。 本发明还涉及一种用于磁稳定三维组织培养的连续流动自调节闭合系统生物反应器系统。 这里描述的方法不使用传统的固体支架进行细胞培养。

公开(公告)号：WO2011109745A2

公开(公告)日：2011-09-09

申请号：PCT/US2011/027256

申请日：2011-03-04

Applicant: WORCESTER POLYTECHNIC INSTITUTE ,  WEATHERS, Pamela, J.

Inventor： WEATHERS, Pamela, J.

CPC classification number: A61K36/282 ,  A61K31/366 ,  A61K45/06 ,  Y02A50/411 ,  Y02A50/423 ,  A61K2300/00

Abstract: The present invention features compositions and methods for treatment of parasitic diseases and cancer. The compositions include Artemisia annua tissue and a pharmaceutically acceptable carrier. The methods provide an efficient delivery system for artemisinin and related compounds.

Abstract translation: 本发明的特征在于用于治疗寄生虫病和癌症的组合物和方法。 组合物包括青蒿组织和药学上可接受的载体。 该方法为青蒿素及相关化合物提供了有效的输送系统。

公开(公告)号：WO2008121323A8

公开(公告)日：2008-10-09

申请号：PCT/US2008/004061

申请日：2008-03-28

Applicant: WORCESTER POLYTECHNIC INSTITUTE ,  HEFFERNAN, Neil, T.

Inventor： HEFFERNAN, Neil, T.

IPC: G09B7/02

Abstract: A global computer network method and apparatus for creating and deploying many types of self-tutoring systems across many different platforms is disclosed. A run time engine supports several types of tutorials, in both a client and server context. A Builder enables development and testing of tutorials, formed of teacher composed problems, or an existing approved problems set, or student-user composed problems. The system simplifies the process of tutorial construction to allow educators and students with little or no ITS experience to develop content of problems and teaching strategies (i.e., format of problems including hints, messages and sequencing of related problems). The system provides a Web based interface as a means to build and store these tutorials. A web based reporting component allows for live database reporting to teachers, showing how students are performing. A testing component is web based and allows a teacher to test the quality of student composed problems. Further, the testing component allows addition of the student content to the existing approved problem set as is pertinent. Automated analysis and reporting of experimental tutorials developed by either teacher or student is included.

公开(公告)号：WO2008031091A2

公开(公告)日：2008-03-13

申请号：PCT/US2007/078005

申请日：2007-09-10

Applicant: WORCESTER POLYTECHNIC INSTITUTE ,  MCGIMPSEY, W., Grant ,  WANICHACHEVA, Nantanit ,  LAMBERT, Christopher, R.

Inventor： MCGIMPSEY, W., Grant ,  WANICHACHEVA, Nantanit ,  LAMBERT, Christopher, R.

IPC: C07K7/54

CPC classification number: C07D273/00

Abstract: A compound sensitive to and selective for ammonium ions over other ions. A sensor fabricated from a self assembled monolayer of said compound on gold, exhibiting sensitivity and selectivity for ammonium ions over other ions in aqueous solutions, including blood. A method of preparation of said compound and said sensor.

Abstract translation: 对其他离子敏感和选择铵离子的化合物。 一种由金组成的所述化合物的自组装单层制成的传感器，对水溶液（包括血液）中的其他离子表现出对铵离子的敏感性和选择性。 一种制备所述化合物和所述传感器的方法。

公开(公告)号：WO2006113440A2

公开(公告)日：2006-10-26

申请号：PCT/US2006/014079

申请日：2006-04-14

Applicant: WORCESTER POLYTECHNIC INSTITUTE ,  MCGIMPSEY, Grant, W. ,  LAMBERT, Christopher, R. ,  BENCO, John, S. ,  THALLADI, Venkat, R.

Inventor： MCGIMPSEY, Grant, W. ,  LAMBERT, Christopher, R. ,  BENCO, John, S. ,  THALLADI, Venkat, R.

IPC: G01N21/64 ,  G01N27/333 ,  G01N33/487

CPC classification number: B82Y15/00 ,  B82Y30/00 ,  B82Y40/00 ,  G01N21/6428 ,  G01N33/54373 ,  G01N33/5438

Abstract: In various aspects are provided a microfluidic and/or nanofluidic sensor that can provide an indication of the reliability of its measurement of the presence of an analyte in a sample under investigation, an analyte concentration in the sample under investigation, or both. The provided sensors, microfluidic devices, and methods of analyte detection, utilize two transduction mechanisms from the same molecule to determine analyte presence, analyte concentration, or both. An analyte sensing molecule is used that can provide both an optical signal and electrochemical signal when an analyte is recognized by an analyte binding portion of the sensing molecule.

Abstract translation: 在各个方面提供了一种微流体和/或纳流感传感器，其可以提供其测量被研究样品中分析物的存在的可靠性的指示，所研究的样品中的分析物浓度或两者。 所提供的传感器，微流体装置和分析物检测方法利用来自相同分子的两个转导机制来确定分析物存在，分析物浓度或两者。 使用分析物感测分子，当分析物被感测分子的分析物结合部分识别时，可以提供光学信号和电化学信号。

公开(公告)号：WO2006034100A1

公开(公告)日：2006-03-30

申请号：PCT/US2005/033289

申请日：2005-09-19

Applicant: SHELL OIL COMPANY ,  WORCESTER POLYTECHNIC INSTITUTE ,  WELLINGTON, Scott Lee ,  MATZAKOS, Andreas Nicholas ,  MARDILOVICH, Ivan Petrovich ,  MA, Yi Hua ,  ENGWALL, Erik Edwin

Inventor： WELLINGTON, Scott Lee ,  MATZAKOS, Andreas Nicholas ,  MARDILOVICH, Ivan Petrovich ,  MA, Yi Hua ,  ENGWALL, Erik Edwin

IPC: B01J8/02 ,  C01B3/50 ,  B01D53/22

CPC classification number: B01J8/009 ,  B01D53/228 ,  B01D67/0069 ,  B01D67/0088 ,  B01D69/10 ,  B01D69/12 ,  B01D71/022 ,  B01D71/025 ,  B01D2325/20 ,  B01D2325/32 ,  B01J19/2475 ,  C01B3/384 ,  C01B3/505 ,  C01B2203/0233 ,  C01B2203/041 ,  C01B2203/047 ,  C01B2203/0475 ,  C01B2203/048 ,  C01B2203/0495 ,  C01B2203/86 ,  F23C2900/99001 ,  Y02E20/342 ,  Y02P30/30

Abstract: A hydrogen producing reactor is disclosed. The hydrogen producing reactor has a reaction chamber containing a catalyst bed adapted to produce reaction products con-taining hydrogen from a hydrogen-producing feedstock. The reaction chamber also in-cludes a hydrogen-selective, hydrogen-permeable gas separation module adapted to re-ceive the reaction products from the catalyst bed and to separate a product stream con-taining hydrogen from the reaction products. The gas separation module comprises a porous substrate, an intermediate porous layer located at the porous substrate, and a hy-drogen-selective membrane overlying the intermediate layer. The intermediate porous layer comprises a powder having a Tamman temperature higher than the Tamman tem-perature of the porous substrate. A steam reforming process is also disclosed using the disclosed reactor.

Abstract translation: 公开了一种制氢反应器。 制氢反应器具有含有催化剂床的反应室，该催化剂床适用于产生从产氢原料获得氢的反应产物。 反应室还包括氢选择性的，氢气可渗透的气体分离模块，其适用于从催化剂床中重新获得反应产物并分离出与反应产物相连的产物流。 气体分离模块包括多孔基材，位于多孔基材处的中间多孔层和覆盖中间层的氢选择性膜。 中间多孔层包括具有高于多孔基材的Tamman温度的Tamman温度的粉末。 还公开了使用所公开的反应器的蒸汽重整方法。