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公开(公告)号：KR1020120058863A
公开(公告)日：2012-06-08
申请号：KR1020100120370
申请日：2010-11-30
Applicant: (주)아모레퍼시픽
CPC classification number: G01N33/573 , G01N2333/96466 , G01N2800/20 , A61Q19/004 , A61Q19/007 , C12Q1/68 , C12Q1/686 , C12Q2600/148 , C12Q2600/158
Abstract: PURPOSE: A method for screening a material for treating dry skin is provided to prevent skin moisturizing and to recover skin barrier. CONSTITUTION: A method for screening a material for treating dry skin comprises a step of screening candidate materials based on expression change of bleomycin hydolase(BH) gene. The gene expression level is measured by PCR. An external use skin composition contains LXR activator which enhances BH gene expression level as an active ingredient. The composition is used for treating dry skin or moisturizing skin.
Abstract translation: 目的：提供一种筛选用于治疗干性皮肤的材料的方法，以防止皮肤保湿并恢复皮肤屏障。 构成：筛选用于治疗干性皮肤的材料的方法包括基于博来霉素水解酶（BH）基因的表达变化筛选候选物质的步骤。 通过PCR测定基因表达水平。 外用皮肤组合物含有增强BH基因表达水平作为活性成分的LXR活化剂。 该组合物用于治疗干性皮肤或保湿皮肤。
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公开(公告)号：KR101154616B1
公开(公告)日：2012-06-08
申请号：KR1020040117888
申请日：2004-12-31
Applicant: (주)아모레퍼시픽
IPC: A61K31/352
CPC classification number: A61Q19/08 , A61K8/498 , A61K8/735 , A61K31/352 , A61K31/7048 , A61Q19/007
Abstract: 본발명은캄페롤(Kaempferol) 및퀘르세틴(Quercetin) 중어느하나이상을함유하는히알루론산생성촉진용조성물에관한것으로서, 본발명의캄페롤또는퀘르세틴은인간표피피부세포주에존재하는히알루론산합성효소(hyaluronic acid synthase; HAS) 유전자의발현을증가시켜인체세포에서히알루론산(hyaluronic acid) 생성을촉진하는효능이있으므로, 본발명에의한캄페롤및 퀘르세틴중 어느하나이상을함유하는조성물은히알루론산생성촉진용조성물로서, 피부탄력증진, 피부건조방지또는피부노화방지용화장료조성물, 또는퇴행성관절염치료또는예방용약학조성물로유용하게사용될수 있다.
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公开(公告)号：KR1020120055924A
公开(公告)日：2012-06-01
申请号：KR1020100117380
申请日：2010-11-24
Applicant: (주)아모레퍼시픽
CPC classification number: A61B5/443 , A61B5/0082 , A61B5/1032 , G01N21/17
Abstract: PURPOSE: A method for evaluating transparent feeling of skin is provided to accurately and objectively evaluate the transparent degree of the skin in which cosmetic material is spread by using permeability of light. CONSTITUTION: A first substrate collecting a skin sample is obtained. The permeability of light of the first substrate is measured. The permeability of the light of the first substrate is the sum of the permeability of the light measured at 0degree and 90degrees of a polarizing filter. A second substrate coating the first substrate with cosmetic material is obtained. The permeability of the light of the second substrate is measured. The degree of relative permeability is calculated by using the permeability of the light of the first substrate and the second substrate.
Abstract translation: 目的：提供一种评价皮肤透明感的方法，以准确，客观地评价使用透光性的化妆品散布的皮肤的透明度。 构成：获得收集皮肤样品的第一底物。 测量第一衬底的光的透过率。 第一衬底的光的透过率是在0度和偏振滤光器的90度处测量的光的磁导率的总和。 获得用化妆品材料涂覆第一基材的第二基材。 测量第二基板的光的透过率。 通过使用第一基板和第二基板的光的磁导率来计算相对磁导率的程度。
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公开(公告)号：KR1020120054861A
公开(公告)日：2012-05-31
申请号：KR1020100116210
申请日：2010-11-22
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A method for evaluating persistency of an UV protection agent is provided to quickly and accurately evaluate the persistency. CONSTITUTION: A method for evaluating persistency of an UV protection agent comprises: a step of measuring the content of UV protection agent remaining in a skin sample on which the UV protection agent; a step of irradiating artificial UV ray onto the skin and measuring the content of the UV protection agent; and a step of calculating relative residual ratio of the UV protection agent.
Abstract translation: 目的：提供一种评估UV保护剂持久性的方法，以快速准确地评估持久性。 构成：用于评估UV保护剂的持续性的方法包括：测量残留在其上具有UV保护剂的皮肤样品中的UV保护剂的含量的步骤; 将人造紫外线照射到皮肤上并测量紫外线防护剂的含量的步骤; 以及计算所述紫外线防护剂的相对残留率的步骤。
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公开(公告)号：KR1020120020960A
公开(公告)日：2012-03-08
申请号：KR1020100084921
申请日：2010-08-31
Applicant: (주)아모레퍼시픽
CPC classification number: A61B5/442 , A61B5/0059 , A61B5/064 , A61B5/7289
Abstract: PURPOSE: A method for measuring skin elasticity using a moire image is provided to conveniently calculate an objective elastic index of skin by measuring average the contour interval and angle value of subjects. CONSTITUTION: Moire images of a plurality of subjects are recorded. Landmarks are respectively set on the plurality of the moire images recorded. A representative image is manufactured by composing images so that the landmarks are overlapped. A contour interval in a composed representative moire image is calculated. An angle of the contour is measured. The elastic index of skin is calculated from the interval or angle of the contour. A preparation process for adopting skin for 15 minutes is operated under the constant temperature of 23°C and the constant humidity condition of the RH 40%.
Abstract translation: 目的：提供使用莫尔图像测量皮肤弹性的方法，通过测量受试者的轮廓间隔和角度值的平均值来方便地计算皮肤的客观弹性指数。 构成：记录多个被摄体的莫尔图像。 在所记录的多个莫尔图像上分别设置地标。 通过组合图像来制作代表性图像，使得地标重叠。 计算组成的代表性莫尔图像中的轮廓间隔。 测量轮廓的角度。 皮肤的弹性指数是根据轮廓的间隔或角度计算的。 采用皮肤15分钟的制备方法在23℃的恒温和RH 40％的恒定湿度条件下进行。
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Patent Agency Ranking
公开(公告)号：KR1020120009774A
公开(公告)日：2012-02-02
申请号：KR1020100070444
申请日：2010-07-21
Applicant: (주)아모레퍼시픽
IPC: G01N33/483 , G01N33/15 , A61K8/68 , C40B30/06
CPC classification number: G01N33/4833 , A61K8/68 , C40B30/06 , G01N33/15
Abstract: PURPOSE: A method for evaluating skin moisturizing ability is provided to quickly and accurately distinguish CER(NS) in a horny substance and to screen a product for enhancing moisturizing ability. CONSTITUTION: A method for evaluating skin moisturizing ability comprises: a step of preparing a sample from a test person; a step of measuring TEWL(transepidermal water loss) of the sample; a step of measuring each content of 8 kinds of ceramides(C16Cer, C18Cer, C18:1Cer, C20Cer, C24Cer, C24:1Cer, C16SM and C18SM) by chromatography; a step of drawing correlation function of TEWL and each ceramide content; and a step of digitizing the skin moisturizing ability of the test person. The ceramide content is measured by UPLC-MS/MS-ESI.
Abstract translation: 目的：提供一种评价皮肤保湿能力的方法，以快速，准确地区分角质物质中的CER（NS），并筛选产品以增强保湿能力。 构成：评价皮肤保湿能力的方法包括：从试验人员制备样品的步骤; 测量样品的TEWL（经皮水分流失）的步骤; 通过色谱法测定8种神经酰胺（C16Cer，C18Cer，C18：1Cer，C20Cer，C24Cer，C24：1Cer，C16SM和C18SM）的每种含量的步骤; 绘制TEWL的相关函数和每种神经酰胺含量的步骤; 以及测试者的皮肤保湿能力的数字化步骤。 神经酰胺含量通过UPLC-MS / MS-ESI测定。
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公开(公告)号：KR1020110088933A
公开(公告)日：2011-08-04
申请号：KR1020100008675
申请日：2010-01-29
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A capsule formulation with stabilized whitening ingredients and cosmetic composition for skin whitening is provided to effectively block swelling of a whitening agent due to water and surfactant. CONSTITUTION: A capsule formulation for whitening with whitening ingredients contains a lipid lamella layer and a polymer layer. The lipid lamella layer exists on a nucleating agent and contains ceramide, phospholipid, and whitening ingredients. The ceramide is natural ceramide or ceramide analogue. The phospholipid is selected from phosphatidyl choline, phosphatidyl serine, phosphatidyl glycerol, and phosphatidic acid. The whitening ingredients is selected from the group consisting of ellagic acid, Rabdosia Rubescens extract, Saxifraga furumiii extract, grape extract, Scutellariae radix extract, and acetyltetrapeptide-11.
Abstract translation: 目的：提供具有稳定的美白成分和用于皮肤美白的化妆品组合物的胶囊制剂，以有效阻止由于水和表面活性剂引起的增白剂的膨胀。 构成：用美白成分增白的胶囊制剂含有脂质层层和聚合物层。 脂质层层存在于成核剂上并含有神经酰胺，磷脂和美白成分。 神经酰胺是天然神经酰胺或神经酰胺类似物。 磷脂选自磷脂酰胆碱，磷脂酰丝氨酸，磷脂酰甘油和磷脂酸。 美白成分选自鞣花酸，茄子提取物，蔷薇提取物，葡萄提取物，黄芩提取物和乙酰四肽-11。
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公开(公告)号：KR1020110047717A
公开(公告)日：2011-05-09
申请号：KR1020090104459
申请日：2009-10-30
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A composition containing flower extract of Castanea crenata is provided to suppress neurotransmitter release and sebum secretion. CONSTITUTION: A composition for tightening pore or suppressing sebum secretion contains 0.0001-30 weight% of flower extract of Castanea crenata as an active ingredient. The flower extract of Castanea crenata is isolated by water, ethanol, or hydrous methanol. The composition is a pharmaceutical composition or cosmetic composition.
Abstract translation: 目的：提供一种含有蓖麻花提取物的组合物，以抑制神经递质释放和皮脂分泌。 构成：用于收紧毛孔或抑制皮脂分泌物的组合物含有0.0001-30重量％的仙人掌花提取物作为活性成分。 蓖麻花提取物用水，乙醇或含水甲醇分离。 该组合物是药物组合物或化妆品组合物。
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公开(公告)号：KR100967114B1
公开(公告)日：2010-07-05
申请号：KR1020030091924
申请日：2003-12-16
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 피부를 투과할 수 없는 큰 분자량을 갖는 양친성 고분자를 유화 안정화제로 사용하여 제조한 에멀젼 타입의 피부 외용제 조성물에 관한 것이다. 보다 상세하게는 오일과 물로 구성된 에멀젼을 저분자량의 계면활성제 또는 유화제의 사용을 배제하고 오직 폴리카프로락톤을 소수성 세그먼트로 갖는 양친성 고분자로 안정화할 수 있는 피부 외용제 조성물에 관한 것이다.
상기의 양친성 고분자는 1) 피부에 투과되지 않아 보다 피부에 안전하고, 2) 오일성분 중 짧은 시간 안에 피부에 자극을 유발하는 특성을 지니고 있는 오일을 피부에 흡수되는 속도를 지연시켜 오일에 의한 자극을 완화하고, 3) 고분자 사슬 간의 응집력(cohesive force)이 매우 우수한 반면, 피부와의 상호작용이 적기 때문에 끈적임이 없어 보다 산뜻한 느낌을 피부에 부여하는 기능을 한다.
양친성 고분자 * 폴리카프로락톤 * 응집력 * 에멀젼 * 피부 외용제 * 피부안전성-
公开(公告)号：KR100962988B1
公开(公告)日：2010-06-10
申请号：KR1020030007885
申请日：2003-02-07
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 머스크(Musk)를 유효성분으로 함유하는 피부건조 개선용 외용제 조성물에 관한 것으로, 보다 상세하게는 상기의 외용제 조성물은 유효성분으로 Musk를 함유하여 피부세포의 분화를 촉진시켜 각질의 재생산을 돕고 피부에 보습기능을 담당하고 있는 천연보습인자(natural moisturizing factor, NMF)를 생산하며, 또한 피부 내부로부터 수분유지에 필요한 지질의 합성을 증가시킴으로써 피부의 수분함유능력 증강, 피부 건조의 방지, 및 아토피(atopy)와 접촉성 피부염 증상 등의 예방, 개선 또는 치료에 우수한 효과를 나타낸다.
Musk * 보습 * 표피 세포 분화 * 필라그린 * 지질생합성 * 세라마이드 * 천연보습인자 * 피부건조 * 아토피 * 접촉성 피부염
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