公开(公告)号：WO98038907A1

公开(公告)日：1998-09-11

申请号：PCT/US1998/004364

申请日：1998-03-06

IPC: A61B1/04 ,  A61B1/00 ,  A61B1/002 ,  A61B1/07 ,  A61B5/00 ,  G01B9/02 ,  G11B7/00

CPC classification number: A61B1/00188 ,  A61B1/00096 ,  A61B1/00172 ,  A61B1/00183 ,  A61B1/002 ,  A61B1/043 ,  A61B1/07 ,  A61B5/0066 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/415 ,  A61B5/417 ,  A61B5/418 ,  A61B5/6852 ,  G01B9/0201 ,  G01B9/02022 ,  G01B9/0205 ,  G01B9/02063 ,  G01B9/02091 ,  G01B2290/65 ,  G11B2007/0013

Abstract: An imaging system includes forward directed optical coherence tomography (OCT), and non-retroreflected forward scanning OCT, and also interferometric imaging and ranging techniques and fluorescent, Raman, two-photon, and diffuse wave imaging can be used. The forward scanning mechanisms include a cam (70) attached to a motor (61), pneumatic devices (96), a pivoting device (90, 94), piezoelectric transducers (74), electrostatic driven slides (108) for substantially transverse scanning; counter-rotating prisms (144), and offset lenses (62) are used for arbitrary scanning. The imaging system of the invention is applied to hand held probes including probes integrated with surgical probes, scalpels, scissors, forceps and biopsy instruments. Hand held probes include forward scanning lasers. The imaging system is also applicable to laparoscopes and endoscopes for diagnostic and therapeutic intervention in body orifices, canals, tubes, ducts, vessels and cavities of the body.

Abstract translation: 成像系统包括前向光学相干断层扫描（OCT）和非回归正向扫描OCT，还可以使用干涉成像和测距技术以及荧光，拉曼，双光子和漫射波成像。 前向扫描机构包括附接到电动机（61）的凸轮（70），气动装置（96），枢转装置（90,94），用于基本上横向扫描的压电换能器（74），静电驱动滑块（108） 反向旋转棱镜（144）和偏移透镜（62）用于任意扫描。 本发明的成像系统应用于手持式探针，其包括与外科手术探针，解剖刀，剪刀，镊子和活检器械集成的探针。 手持式探头包括正向扫描激光器。 成像系统还适用于腹腔镜和内窥镜，用于身体孔，运河，管，管道，血管和体腔的诊断和治疗干预。

公开(公告)号：WO1992019930A1

公开(公告)日：1992-11-12

申请号：PCT/US1992003536

申请日：1992-04-29

Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY ,  SWANSON, Eric, A.

Inventor： MASSACHUSETTS INSTITUTE OF TECHNOLOGY ,  SWANSON, Eric, A. ,  HUANG, David ,  FUJIMOTO, James, G. ,  PULIAFITO, Carmen, A. ,  LIN, Charles, P. ,  SCHUMAN, Joseph, S.

IPC: G01B09/02

CPC classification number: G02B26/0875 ,  A61B1/00096 ,  A61B1/00172 ,  A61B1/00183 ,  A61B3/102 ,  A61B5/0064 ,  A61B5/0066 ,  A61B5/0068 ,  A61B5/0084 ,  A61B5/441 ,  A61B5/6852 ,  A61B2562/0242 ,  B82Y15/00 ,  G01B9/02002 ,  G01B9/0201 ,  G01B9/02019 ,  G01B9/02027 ,  G01B9/02063 ,  G01B9/02087 ,  G01B9/0209 ,  G01B11/00 ,  G01B11/2441 ,  G01B2290/45 ,  G01B2290/65 ,  G01B2290/70 ,  G01J1/00 ,  G01N21/4795 ,  G02B5/1828 ,  G02B26/103 ,  G11B2007/0013 ,  H01S5/141

Abstract: A method and apparatus for performing optical imaging on a sample wherein longitudinal scanning or positioning in the sample is provided by either varying relative optical path lengths for an optical path leading to the sample and to a reference reflector (32), or by varying an optical characteristic of the output from an optical source applied to the apparatus. Transverse scanning in one or two dimensions is provided on the sample by providing controlled (28) relative movement between the sample and a probe module in such direction and/or by steering optical (18) radiation in the probe module to a selected transverse position. The probe module may be an external module or may be an endoscope or angioscope utilized for scanning internal channels.

Abstract translation: 一种用于对样品进行光学成像的方法和装置，其中样品中的纵向扫描或定位是通过改变相对于通向样品的光路和参考反射器（32）的相对光程长度而提供的，或者通过改变光学 来自施加到该装置的光源的输出的特性。 通过在样品和探针模块之间以这种方向和/或通过将探针模块中的光学（18）辐射转向到选定的横向位置来提供受控（28）的相对运动，在样品上提供一维或二维的横向扫描。 探针模块可以是外部模块，也可以是用于扫描内部通道的内窥镜或血管造影仪。

公开(公告)号：EP4409225A1

公开(公告)日：2024-08-07

申请号：EP22793472.6

申请日：2022-09-22

Applicant: Lidwave Ltd.

Inventor： HAI VIDAL, Yehuda ,  WEISS, Uri

IPC: G01B9/02015 ,  G01B9/02001

CPC classification number: G01B9/02028 ,  G01B9/0201

公开(公告)号：EP2317923B1

公开(公告)日：2018-04-04

申请号：EP09800879.0

申请日：2009-07-21

Applicant: Optovue, Inc.

Inventor： KO, Tony ,  ZHAO, Yonghua ,  HUANG, David

IPC: A61B5/00 ,  A61B3/10 ,  A61B3/00 ,  G01B9/02

CPC classification number: A61B3/102 ,  A61B3/0025 ,  A61B5/0066 ,  A61B5/0073 ,  A61B5/7257 ,  G01B9/02004 ,  G01B9/0201 ,  G01B9/02021 ,  G01B9/02028 ,  G01B9/02044 ,  G01B9/02091

Abstract: An imager that can provide separated images corresponding to differing depths in a sample is presented. In accordance with some embodiments of the invention, an imager can include a light source; a sample arm that receives light from the light source, directs the light to a sample, and captures light returning from the sample; a modulation source that provides different modulations corresponding to differing imaging depths in the sample; a detector system to receive the captured light from the sample with the different modulations; and a processor that receives signals from the detector system and separates a plurality of images corresponding with the differing image depths in the sample.

公开(公告)号：EP3054274A1

公开(公告)日：2016-08-10

申请号：EP16154687.4

申请日：2016-02-08

Applicant: The State Scientific Institution "B.I. Stepanov Institute of Physics of National Academy of Sciences of Belarus" ,  The State Scientific Institution "Institute of Chemistry of New Materials of National Academy of Sciences of Belarus" ,  King Abdulaziz City for Science and Technology

Inventor： AGASHKOV, Alexander Vasilevich ,  KAZAK, Nikolai Stanislavovich ,  AGABEKOV, Vladimir Enokovich ,  ALSHAMMARI, Marzook Saleh ,  BINHUSSAIN, Mohammed

IPC: G01J9/02

CPC classification number: G01B9/02011 ,  G01B9/0201 ,  G01J9/02

Abstract: An interferometer includes a tunable laser source (1) of coherent radiation generating an input beam; a first polarizer (2) configured to transmit a polarized beam with adjustable intensities of orthogonally polarized components; a broadband non-polarizing beam splitter (3) forming two optically connected arms (I; II), first one with a transmitted beam, and sequentially comprising a birefringent element (4) configured to split the polarized input beam into two separate, parallel, orthogonally polarized reference beam and object beam and mounted on the base (5) with fine rotation, the birefringent element acts as both the splitter and the combiner in an interferometer; and a sample (6) with means of its shifting and inclining; and a chopper wheel (10) with a system of holes that opens sequentially for some time object and reference beams separately, then simultaneously, providing interference of said beams; and a broadband plane mirror (11) reflecting incident object and reference beams in the opposite direction and providing double passing of the beams through the sample and the birefringent element which converts two said beams into orthogonally polarized components of a single output beam falling on a non-polarizing beam splitter; this beam, been reflected, forms the second arm (II) of the interferometer, where there are sequentially arranged a controllable phase retarder (12), configured to introduce phase shift only into one polarization component of a said beam; and the second polarizer (13) that equalizes and mixes the polarization components of the input said beam and transforms input said beam into a beam, which is the result of interference of polarization components of the input beam; and a photodetector (14) configured to receive an input beam and transform an intensity of the beam into output electric signal (27), which can be amplified and analyzed by various electronic devices.

Abstract translation: 干涉仪包括产生输入光束的相干辐射的可调谐激光源（1）; 第一偏振器（2），被配置为透射具有可调强度的正交极化分量的偏振光束; 形成两个光学连接的臂（I; II）的宽带非偏振分束器（3），第一个具有透射光束，并且顺序地包括双折射元件（4），该双折射元件被配置为将偏振输入光束分成两个分开的， 正交极化参考光束和物体光束并以精细旋转安装在基座（5）上，双折射元件用作干涉仪中的分束器和组合器; 和具有其移动和倾斜的装置的样品（6）; 以及具有孔的系统的切割轮（10），其分开地依次打开一段时间的物体和参考光束，然后同时提供所述光束的干涉; 以及反射入射物体和参考光束的相反方向的宽带平面镜（11），并且提供光束通过样本的双重通过以及将两个所述光束转换成垂直于非单一输出光束的正交极化分量的双折射元件 极化分束器; 该光束被反射形成干涉仪的第二臂（II），其中依次布置有可控相位延迟器（12），其被配置为仅将相移仅引入所述光束的一个偏振分量; 以及第二偏振器（13），其均衡和混合输入所述光束的偏振分量，并将输入的所述光束变换为光束，其是输入光束的偏振分量的干扰的结果; 以及光电检测器（14），被配置为接收输入光束并将光束的强度变换成输出电信号（27），其可以由各种电子设备放大和分析。

公开(公告)号：EP2175258A4

公开(公告)日：2015-06-24

申请号：EP08765011

申请日：2008-06-03

Applicant: HAMAMATSU PHOTONICS KK

Inventor： IWAI HIDENAO ,  YAMAUCHI TOYOHIKO

IPC: G01N21/45 ,  G01B9/02 ,  G01B11/06

CPC classification number: G01B9/02069 ,  G01B9/0201 ,  G01B11/06 ,  G01B2290/35 ,  G01N21/45

公开(公告)号：EP2572158A1

公开(公告)日：2013-03-27

申请号：EP11724366.7

申请日：2011-05-18

Applicant: Hochschule Trier

Inventor： SCHUTH, Michael ,  ROBERT, Dietmar ,  NÄGEL, Daniel

IPC: G01B9/02 ,  G01B11/24

CPC classification number: G01B11/164 ,  G01B9/0201 ,  G01B9/02072 ,  G01B9/02095

Abstract: The invention relates to optical measurement systems and optical measurement methods on the basis of digital holography for measuring at least one component of the deformation and/or expansion of a measurement object in at least one prespecified or prespecifiable direction using digital holography. The optical measurement system comprises a digital holography apparatus (12, 12-1, 12-2, 12-3) for illuminating a scanning region of a measurement object, which digital holography apparatus has an out-of-plane and/or and in-plane digital holography arrangement with at least two coherent beams, and a microscope objective (24), the optical axis of which is substantially parallel to a vertical direction and which is arranged in the optical path of the at least one part of the light reflected by the measurement object (22), wherein, when viewed in the vertical direction, the digital holography apparatus (12, 12-1, 12-2, 12-3) is arranged below or above the microscope objective (24) and/or a microscope base body.

Abstract translation: 基于数字全息术的光学测量系统和光学测量方法技术领域本发明涉及基于数字全息术的光学测量系统和光学测量方法，用于使用数字全息术在至少一个预先指定的或可预先确定的方向上测量测量对象的变形和/或扩展的至少一个分量。 该光学测量系统包括用于照射测量对象的扫描区域的数字全息设备（12,12-1,12-2,12-3），该数字全息设备具有平面外和/或平面内和/或平面内 - 具有至少两个相干光束的平面数字全息装置，以及 - 显微镜物镜（24），其光轴基本上平行于垂直方向并且被布置在至少一部分反射光的光路中 通过所述测量对象（22），其中当沿垂直方向观看时，所述数字全息设备（12,12-1,12-2,12-3）被布置在所述显微镜物镜（24）的下方或上方和/或 一个显微镜基体。

公开(公告)号：EP2347216A1

公开(公告)日：2011-07-27

申请号：EP09748278.0

申请日：2009-10-19

Applicant: Siemens Aktiengesellschaft

Inventor： DUDECK, Sven, Gerhard ,  GERHARD, Detlef ,  HIRTH, Florian ,  JAKOBI, Martin

IPC: G01B11/06 ,  G01B11/24 ,  G01N21/95

CPC classification number: G01B11/0691 ,  G01B9/0201 ,  G01B9/02014 ,  G01B9/02035 ,  G01B9/0209 ,  G01B11/2441 ,  G01N21/9501 ,  G01N21/95684 ,  G01N2021/8438

Abstract: The invention relates to an interferometry method for optically examining coatings. This can be carried out as a white light interferometry or spectral thin-film interferometry method, for example. In the process, a measuring spot (18) is generated with a diameter (d), said spot used to optically examine the surface (12) of a measured object (11). According to the invention, the method is carried out on a measured object (11) with velocity (v), wherein the illumination of the measured object is done with light pulses of a duration (t). In the process, the fact that the extent (a) of the coating section to be examined must be greater than d + vt in order to perform a measurement must be taken into account. According to the invention, the parameters (d, v and t) are suitably selected for a pre-determined velocity (v) of the measured object. The measurement method can therefore be advantageously applied in ongoing, continuous production of coated components.

公开(公告)号：EP1604168B1

公开(公告)日：2011-07-27

申请号：EP04718544.2

申请日：2004-03-08

Applicant: ZYGO CORPORATION

Inventor： DE GROOT, Peter, J. ,  STONER, Robert ,  COLONNA DE LEGA, Xavier

IPC: G01B9/02

CPC classification number: G01B9/0201 ,  G01B9/02057 ,  G01B9/02084 ,  G01B9/02088 ,  G01B9/0209 ,  G01B11/0675 ,  G01B2290/70

Abstract: A method including comparing information derivable from a scanning interferometry signal for a first surface location of a test object to information corresponding to multiple models of the test object, wherein the multiple models are parametrized by a series of characteristics for the test object. The derivable information being compared may relate to a shape of the scanning interferometry signal for the first surface location of the test object.

公开(公告)号：EP1888999A2

公开(公告)日：2008-02-20

申请号：EP06784475.3

申请日：2006-05-23

Applicant: Southwest Sciences Incorporated

Inventor： VAKHTIN, Andrei, B. ,  KANE, Daniel, J. ,  PETERSON, Kristen, A.

IPC: G01B9/02

CPC classification number: G01J3/45 ,  G01B9/02004 ,  G01B9/0201 ,  G01B9/02044 ,  G01B9/02081 ,  G01B9/02091 ,  G01B2290/45

Abstract: An apparatus and method for differential spectral interferometry comprising providing an interferometer comprising a light source; employing an element to provide a dithered relative phase shift between target and reference arms of the interferometer, detecting output from the interferometer, demodulating signals received from the detector at different multiples of the dither frequencies, generating more than one real-valued interferograms from demodulated signals, and using the real- valued interferograms to obtain the complex spectral interferogram.