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    Automatic chemical analyzer
    101.
    发明授权
    Automatic chemical analyzer 失效
    自动化学分析仪

    公开(公告)号：US4939095A

    公开(公告)日：1990-07-03

    申请号：US370079

    申请日：1989-06-22

    Applicant: Noboru Yokotani

    Inventor： Noboru Yokotani

    IPC: G01N21/75 ,  G01N21/27 ,  G01N21/41 ,  G01N21/59 ,  G01N35/02 ,  G01N35/10

    CPC classification number: G01N21/59 ,  G01N21/274 ,  G01N35/1002 ,  G01N2201/04 ,  G01N2201/12753 ,  Y10T436/113332

    Abstract: An automatic chemical analyzer has a compensation coefficient calculating section and a light-path-length-based compensating section. The calculating section obtains the ratio of the absorbancies measured of reaction cells filled with a sample of the known absorbancy to the absorbancy measured of each cell, thereby calculating compensation coefficients for the respective cells. The compensating section multiplies the absorbancies measured of the cells refilled with samples of different unknown absorbancies by the compensation coefficients calculated by the calculating section, thereby compensating the absorbancies for the light path lengths of the cells. The compensated absorbancies, i.e., the absorbancies of the samples, are used in analyzing the samples.

    Abstract translation: 自动化学分析仪具有补偿系数计算部和光路长度补偿部。 计算部分获得了填充有已知吸光度的样品的反应池的吸光度与每个单元的测量吸收度的比率，由此计算各个单元的补偿系数。 补偿部分将由不同未知吸收值的样品重新填充的单元的测量吸收值乘以由计算部分计算出的补偿系数，由此补偿单元的光路长度的吸收率。 补偿的吸收率，即样品的吸收率，用于分析样品。

    METHODS AND SYSTEMS FOR PURE DYE INSTRUMENT NORMALIZATION
    103.
    发明公开
    METHODS AND SYSTEMS FOR PURE DYE INSTRUMENT NORMALIZATION 审中-公开
    纯染料仪器正常化的方法和系统

    公开(公告)号：EP3254082A1

    公开(公告)日：2017-12-13

    申请号：EP16707298.2

    申请日：2016-02-05

    Applicant: Life Technologies Corporation

    Inventor： MARKS, Jeffrey

    IPC: G01N21/27 ,  G01N21/64

    CPC classification number: C12Q1/686 ,  G01N21/274 ,  G01N21/6428 ,  G01N21/6452 ,  G01N2021/6421 ,  G01N2201/04 ,  G01N2201/068 ,  G01N2201/12746

    Abstract: The present teachings relate to a method and system for normalizing spectra across multiple instruments. In an embodiment of the present invention, the method comprises at least one reference instrument and a test instrument. Each instrument comprises at least one excitation filter and at least one emission filter arranged in pairs. Each instrument further comprises a pure dye plate comprising a plurality of wells. Each well contains a plurality of dyes where each dye comprises a fluorescent component. Fluorescent spectra are obtained from each instrument for each dye across multiple filter combinations to contribute to a pure dye matrix Mref for the reference instrument and pure dye matrix M for the test instrument. The pure dye spectra can then be multiplied by correction factors for each filter pair to result in corrected pure dye spectra, then normalized and the multicomponenting data can be extracted.

    PORTABLE AND CARTRIDGE-BASED SURFACE PLASMON RESONANCE SENSING SYSTEMS
    105.
    发明公开
    PORTABLE AND CARTRIDGE-BASED SURFACE PLASMON RESONANCE SENSING SYSTEMS 审中-公开
    便携式和磁带盒的系统控制的表面等离子体共振

    公开(公告)号：EP1872110A2

    公开(公告)日：2008-01-02

    申请号：EP06758285.8

    申请日：2006-04-06

    Applicant: University of Washington

    Inventor： CHINOWSKY, Timothy, M. ,  GROW, Michael, S. ,  TRITZ, Jared ,  FURLONG, Clement, E. ,  KAUFFMAN, Peter, C. ,  SOELBERG, Scott, D. ,  YEE, Sinclair, S. ,  NAIMUSHIN, Alexei, N.

    IPC: G01N21/55

    CPC classification number: G01N21/553 ,  G01N2201/04

    Abstract: Various improvements in the field of SPR sensing systems are disclosed. One improvement relates to a portable SPR sensing system within a suitcase that can be hand-carried to a monitoring site. Another improvement relates to a portable, cartridge-based SPR sensing system, in which selected portions of the system's electrical and fluidics systems are allocated between a base unit and a removable/ disposable cartridge. Other improvements relate to methods or protocols for operating an SPR sensing system, by providing for the elimination of false positives and increased sensitivity by using secondary antibodies with specificity for different target epitopes and by sensor element redundancy. Protocols are provided for the detection of small molecules and employ a competition type assay where the presence of the analyte inhibits the binding of antibodies to surface immobilized analyte, or a displacement assay, where antibodies bound to the analyte on the sensor surface are displaced by free analyte.

    OPTICAL INTERROGATION SYSTEM AND METHOD FOR USING SAME
    106.
    发明公开
    OPTICAL INTERROGATION SYSTEM AND METHOD FOR USING SAME 审中-公开
    光学检查系统和方法使用相同的

    公开(公告)号：EP1636630A1

    公开(公告)日：2006-03-22

    申请号：EP04752701.5

    申请日：2004-05-19

    Applicant: Corning Incorporated

    Inventor： CARRACCI, Stephen, J. ,  FONTAINE, Norman, H.

    IPC: G02B27/10

    CPC classification number: G01N21/253 ,  G01N2201/04 ,  G01N2201/10 ,  G02B27/1086

    Abstract: An optical interrogation system and method are described herein that are capable of generating light beams that have desired optical properties which are directed towards a specimen array. In one embodiment, the optical interrogation system includes a light source, a diffractive element and a collimating optic (e.g., simple lens(es), f-θ lens(es), segmented mirror, fiber array). The light source emits a light beam to the diffractive optic which receives the light beam and outputs an array of light beams to the collimating optic. The collimating optic receives and conditions the light beams emitted from the diffractive optic and then outputs the conditioned light beams which have desired optical properties towards a specimen array. Several other embodiments of the optical interrogation system are also described herein.

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