Abstract:
In a system and method for performing tear film structure measurement and evaporation rate measurements a broadband light source illuminates the tear film and a spectrometer measures respective spectra of reflected light from at least one point of the tear film. A color camera obtains a large field of view image of the tear film so as to obtain color information for all points of the tear film imaged by the color camera and an autofocusing mechanism focusses the color camera and the spectrometer. A processing unit coupled to the camera and to the spectrometer calibrates the camera so that the color obtained by the camera at the at least one point measured by the spectrometer matches the color of the spectrometer at the same point, and determines from the color of each point of the calibrated camera the thickness of the lipids at the respective point.
Abstract:
The concentration of mercury in a sample is measured by a reader secured to a camera-containing mobile electronic device. The reader has holders for sample and control solutions. First and second light sources emitting light at different colors illuminate the sample and control holders. Each holder contains gold nanoparticles, thymine-rich aptamers, and sodium chloride. The light sources illuminate the sample and control holders. An image is captured of the transmitted light through the sample and control holders, wherein the image comprises two control regions of interest and two sample regions of interest. The device calculates the intensity of the two control regions of interest and the two sample regions of interest and generates intensity ratios for the sample and control, respectively, at each color. The device calculates a normalized color ratio based on the intensity ratios and outputs a concentration of mercury based on the normalized color ratio.
Abstract:
Methods and systems for sensor calibration and sensor glucose (SG) fusion are used advantageously to improve the accuracy and reliability of orthogonally redundant glucose sensor devices, which may include optical and electrochemical glucose sensors. Calibration for both sensors may be achieved via fixed-offset and/or dynamic regression methodologies, depending, e.g., on sensor stability and Isig-Ratio pair correlation. For SG fusion, respective integrity checks may be performed for SG values from the optical and electrochemical sensors, and the SG values calibrated if the integrity checks are passed. Integrity checks may include checking for sensitivity loss, noise, and drift. If the integrity checks are failed, in-line sensor mapping between the electrochemical and optical sensors may be performed prior to calibration. The electrochemical and optical SG values may be weighted (as a function of the respective sensor's overall reliability index (RI)) and the weighted SGs combined to obtain a single, fused SG value.
Abstract:
An optical computing device utilizes an Integrated Computational Element ("ICE") core to correct calibration transfer errors in the device by first a ICE core functioning to determine the sample characteristic and a second ICE core acting to correct for calibration transfer errors ("CTEs") introduced by the device components in a variety of ways.
Abstract:
Analyte arrays such as solutes in a slab-shaped gel following electrophoresis, and particularly arrays that are in excess of 3cm square and up to 25cm square and higher, are imaged at distances of 5cm or less by either forming sub- images of the entire array and stitching together the sub-images by computer-based stitching technology, or by using an array of thin-film photoresponsive elements that is coextensive with the analyte array to form a single image of the array.
Abstract:
A system for the qualitative analysis of an agricultural product comprises a scanning cell (1) for the transmittance of a sample of an agricultural product, means for the emission of a quantity of light (6) and means for the detection of a quantity of light (5,50), at least one optical sensor (9,90) and a remote control unit (10) connected to the above mentioned at least one optical sensor (9,90). The system is characterized by the fact that said means for the detection of a quantity of light (5) are mounted in a mobile manner on said cell (1) and arranged frontally to said means of emission of a quantity of light (6), in such a way that the distance between said means of emission (6) and said means of detection (5) can be altered.