Abstract:
The spray dryer comprises a spray drying chamber having a substantially cylindrical top section, a conical wall and a narrowed lower section. In the top section, atomizing means is provided. One or more cameras are associated with the drying chamber in order to monitor the process. At least one of the cameras is an infrared camera adapted for measuring the temperature within a predefined area.
Abstract:
The spray dryer (1) comprises a spray drying chamber(2)having a substantially cylindrical top section (4a), a conical wall (3)and a narrowed lower section (4b). In the top section (4a), atomizing means (9)is provided. One or more cameras (6) are associated with the drying chamber (2) in order to monitor the process. At least one of the cameras is an infrared camera adapted for measuring the temperature within a predefined area.
Abstract:
The air disperser (1) for a spray dryer is provided with a centre (3) having a longitudinal axis defining an axial direction (a) and a radial direction (r). A wall (4) defines a space together with the centre (3), and a plurality of guide vanes (5) is provided in the space. An adjustment device (6, 7, 8) is provided for adjustment of the angular position of the guide vanes (5) about an axis parallel to the radial direction (r), and the adjustment device includes remote operating means, which may include a lever (6) extending from a position outside a duct wall (2) through a part-circumferential slit (7) in the wall (2). The lever (6) may be adapted to be actuated to transfer a rotating movement about the radially extending axis to each of the guide vanes (5) by movement of the lever (6) in the slit (7).
Abstract:
The invention relates to a plant for production of tablets, a process for production of tablets and tablets as such. The plant comprises a mixing device producing a mixed liquid feed of active pharmaceutical ingredient and excipients. A spray dryer atomizes the mixed liquid feed and dried particles with a high flowability are produced. The dried particles are subsequently compressed to tablets in a tablet press. The invention possesses several advantages, including the possibility of using an auto mated rotary tablet press directly, thereby reducing the number of unit operations in the tablet production.
Abstract:
A nozzle for atomising a liquid by means of a gas comprises a mixing chamber (1), one or more liquid inlets (6c) and at least one tangential gas inlet (5) to the mixing chamber. An outlet (4) is positioned at the downstream end of the mixing chamber (1). A centre body (2) having a generally converging configuration, seen in the flow direction, is provided in the mixing chamber (1). The liquid inlet (6c) or inlets is/are positioned at or near the upstream end (3a) of the mixing chamber (1) and in the upstream direction with respect to the gas inlet (5) or inlets.
Abstract:
Disclosed is a method for training an operator of a spray drying plant, the spray drying plant comprising a plurality of plant elements including pre-processing elements, a spray drying element, post-processing elements, powder recovery elements, and a programmable logic controller, PLC. The method comprises the steps of: obtaining a transient model of the spray drying plant, wherein the transient model comprises transient sub-models of the plurality of plant elements; calculating repeatedly simulated sensor data based on the obtained transient model, using a processing unit; displaying on a display a training human machine interface, tHMI, configured to communicate with the transient model of the spray drying plant, and to display the simulated sensor data and control data for the transient model; and updating the transient model based on operator input on the tHMI, for controlling the transient model of the spray drying plant.