公开(公告)号：JPH05107253A

公开(公告)日：1993-04-27

申请号：JP27148291

申请日：1991-10-18

Applicant: ALOKA CO LTD

Inventor： KAWANABE JUNICHI ,  TAKEDA MASAAKI ,  KATAKI HITOMI ,  KATOU YUUKO

IPC: G01N1/00 ,  G01N35/10

Abstract: PURPOSE:To enable a suction time to be reduced when sucking the red cell constituent which is a highly viscous liquid sample. CONSTITUTION:When sucking a red cell constituent by a nozzle chip, a piston is pulled to the maximum, suction is started by generating a maximum suction force, the piston is returned to a target amount of suction when a pressure of the suction system reaches a certain value alpha, and then the target amount of suction is made finally. Since the suction force of a pump can be utilized to the maximum, suction can be speeded up.

公开(公告)号：JPH02262034A

公开(公告)日：1990-10-24

申请号：JP8336089

申请日：1989-03-31

Applicant: ALOKA CO LTD

Inventor： YOSHIMURA TOMOYUKI ,  KAWANABE JUNICHI ,  TAKEDA MASAAKI

IPC: G01N21/35 ,  G01N21/27 ,  G01N21/3577 ,  G01N21/359

Abstract: PURPOSE:To prevent errors in distributing amounts caused by the formation of bubbles and to make analysis and inspection highly accurate by detecting bubbles when the bubbles are formed by the mixing of air when a chip is inputted into a sample in an automatic distributing apparatus which is used for inspecting the samples such as serum, urine, reagent and the like, and stopping the analysis and the inspection of the chip. CONSTITUTION:Near infrared-rays from a near infrared-ray emitting diode 16 is condensed to a certain size in the axial direction of a chip 10 by using a lens 18 and a circular cylinder lens 20. Thus the near infrared rays are inputted. Only the light which has transmitted through this position is inputted into a photodetector 26 through an optical filter 24. At this time, the vacant chip 10 is moved in the direction of an arrow at a constant speed. The amount of the near infrared-rays transmitted through this position is detected with the photodetector 26. The result is stored in a first level memory 34. Then, the chip 10 in which liquid sample is inputted to as not to form bubbles is further moved. The light is detected with the photodetector 26, and the result is stored in a second level memory 36. The amounts of the transmitted light rays stored in the memories 34 and 36 are subtracted in a subtractor 38. The result is compared with a reference value in a reference value memory 42 in a comparator circuit 44.

公开(公告)号：JPS57179661A

公开(公告)日：1982-11-05

申请号：JP6407881

申请日：1981-04-30

Applicant: ALOKA CO LTD

Inventor： TAKEDA MASAAKI ,  OKABE YOSHIFUMI

IPC: G01N33/536 ,  G01N33/53 ,  G01N33/56

Abstract: PURPOSE:To set an accurate standard curve without complicated operations by subjecting the coordinates of the quantity of antigen to log transformation, by estimating values of radioisotope (RI) at times when the quantity of antigen is 0 and infinite, and by subjecting the coordinates of a measured value of RI to logit transformation based on the measured and estimated values. CONSTITUTION:In setting a standard curve at the time when a linked antibody-labelled- antigen substance is measured by utilizing the competitive reaction between antigen in a known quantity and RI-marked antigen in a prescribed quantity so as to analyze the antigen in a sample, the quantity of antigen is made to be x and this is subjected to log transformation. Next, a measured value y of RI corresponding to x is found, and the measured values y of RI at the times when the quantity of antigen is 0 and infinite are supposed from a plurality of known quantities (x) of antigen and the measured values (y) of RI corresponding thereto by using a specific relational expression, and are made to be B0 and N, respectively. Based on these supposed values B0 and N and (y), the measured values (y) of RI are subjected to logit transformation, and the measured values of RI are represented in the standard curve on the coordinates of the respective transformed values by a method of least squares. By using this standard curve, the quantity of antigen in the sample can be determined with little error from the measured values of the RI of the sample.