公开(公告)号：WO2014040727A1

公开(公告)日：2014-03-20

申请号：PCT/EP2013/002728

申请日：2013-09-11

Applicant: DÖBELIN, Werner

Inventor： DÖBELIN, Werner

IPC: F04B11/00 ,  F04B23/06 ,  F04B37/12 ,  G01N30/02 ,  G01N30/32 ,  G01N30/34 ,  G01N30/36

CPC classification number: F04B11/005 ,  F04B1/02 ,  F04B13/02 ,  F04B17/00 ,  F04B23/06 ,  F04B37/12 ,  F04B53/10 ,  F04B53/14 ,  F04B53/16 ,  G01N30/16 ,  G01N30/34 ,  G01N2030/201 ,  G01N2030/202

Abstract: Die Erfindung beschreibt ein Hochdruck-Spritzenpumpensystem für die Anwendung im Bereich der HPLC, UHPLC, Mikro- und Nano-HPLC im Gradientenbetrieb. Die unterschiedlichen Lösungsmittel werden durch passive Rückschlagventile unabhängig komprimiert, die Lösungsmittelzusammenführung erfolgt erst bei gleichem Druck, der Zieldruck für die Initialisierung wir durch eine Regelvorgabe mit höherer Förderleistung erreicht, bei der auch die Kompressibilität berücksichtigt wird. Das Ändern von Lösungsmitteln sowie das Spülen der Pumpenköpfe erfolgt durch getrennte Ein- und Ausgänge im Durchfluss über ein aktives Multipositions-Hochdruckventil, welches auch den Pumpenkopf verschliessen und über das passive Rückschlagventil öffnen kann. Die Regeleinheit und der Antriebsmotor, welcher auch als Kraftsensor dient, erfaßt Kompressibilität, Lufteinschlüsse und Undichtigkeiten. Je nach Ausführung werden die Spritzenpumpenköpfe thermisch stabilisiert.

Abstract translation: 本发明描述了一种用于在HPLC，UHPLC，微米和纳米HPLC梯度的领域中的应用的高压注射泵系统。 不同的溶剂通过被动止回阀独立压缩，该溶剂仅一起发生在相同的压力，因为我们通过在该压缩被认为是较高的流速的控制规范实现的初始化目标压力。 溶剂的变化以及泵压头的冲洗是通过在流分开的输入和输出通过主动多位置高压阀，该阀可以关闭和打开所述泵头部，并通过被动止回阀进行。 控制单元和驱动电机，其也用作力传感器，检测压缩性，气泡和泄漏。 根据不同的实施例中，注射器泵压头进行热稳定化。

公开(公告)号：WO2009108219A2

公开(公告)日：2009-09-03

申请号：PCT/US2008078067

申请日：2008-09-29

Applicant: SCHLUMBERGER SERVICES PETROL ,  SCHLUMBERGER CA LTD ,  SCHLUMBERGER HOLDINGS ,  SCHLUMBERGER TECHNOLOGY BV ,  PRAD RES & DEV LTD ,  SHAH JAGDISH ,  STEINECKER WILLIAM H ,  BOSTROM NEIL WILLIAM ,  RAGHURAMAN BHAVANI

Inventor： SHAH JAGDISH ,  STEINECKER WILLIAM H ,  BOSTROM NEIL WILLIAM ,  RAGHURAMAN BHAVANI

IPC: G01N30/16

CPC classification number: G01N30/04 ,  G01N30/16 ,  G01N30/20 ,  G01N30/22 ,  G01N2030/201 ,  G01N2030/202

Abstract: The present invention generally recites a method, system and apparatus for fluid analysis and more specifically recites a method system and apparatus for multistage injection of a fluid to be analyzed into a fluid analysis instrument.

Abstract translation: 本发明总体上叙述了用于流体分析的方法，系统和装置，并且更具体地说明了用于将要分析的流体多级注射到流体分析仪器中的方法系统和装置。

公开(公告)号：WO2009041442A1

公开(公告)日：2009-04-02

申请号：PCT/JP2008/067199

申请日：2008-09-24

Applicant: 株式会社 島津製作所 ,  前田 愛明 ,  丸山 秀三

Inventor： 前田 愛明 ,  丸山 秀三

IPC: G01N1/00 ,  G01N30/20 ,  G01N30/24 ,  G01N30/26

CPC classification number: G01N30/20 ,  F16K11/074 ,  G01N30/24 ,  G01N35/1097 ,  G01N2030/201 ,  G01N2030/202 ,  Y10T137/4259 ,  Y10T137/86549 ,  Y10T137/86863

Abstract: 【課題】キャリーオーバを低減する。 【解決手段】全量注入方式の試料導入装置で高圧バルブ５１をロード状態からインジェクト状態に切り換えるとき、注入ポート２５に連通するステータ孔ｄと分離・検出部３０へ連通する流路を接続するポートｃとの連通が、送液装置１０に連通するステータ孔ｂとニードル５４に連通するステータ孔ａとの連通よりも早くする。ステータ孔ｄ－ｅ間或いはステータ孔ｄ－ｃ間を連通するロータ溝Ｙの長さを、他のロータ溝Ｘの長さよりも長くする。

Abstract translation: [问题]减少结转。 [解决问题的手段]当全注射系统的样品引入装置的高压阀（51）从负载状态切换到注入状态时，与注入口（25）连通的定子孔（d）是 与端口连通（c）以与定子孔（a）连通的定子孔（b）的连通更高的速度连接与分离/检测部分（30）连通的通道，定子孔（a）连通 用针（54）。 在定子孔（d）和（e）或定子孔（d）和（c）之间连通的转子槽（Y）比另一个转子槽（X）长。

公开(公告)号：WO2008140377A1

公开(公告)日：2008-11-20

申请号：PCT/SE2008/000317

申请日：2008-05-08

Applicant: GE HEALTHCARE BIO-SCIENCES AB ,  KÄLLBACK, Patrick ,  WILÉN, Anders

Inventor： KÄLLBACK, Patrick ,  WILÉN, Anders

IPC: G01N30/20 ,  G01N35/10 ,  F16K11/074

CPC classification number: G01N35/1095 ,  F16K11/0743 ,  G01N35/1097 ,  G01N2030/201 ,  G01N2030/202 ,  Y10T137/86533

Abstract: A rotary valve for selectively connecting at least one component (51, 52) into a fluid path. According to the invention the inner stator face (I l ia, 211a) comprises orifices (131b-136b; 231b- 236b) and said inner rotor face (112a, 212a) comprises at least a first groove (121, 221), a second groove (122, 222), and a third groove (123, 223) so arranged that the rotary valve can take at least three different rotary positions, in which either both components are bypassed, only one of the components is connected and the other bypassed or both components are connected to a main flow.

Abstract translation: 一种用于选择性地将至少一个部件（51,52）连接到流体路径中的旋转阀。 根据本发明，内定子面（111a，211a）包括孔（131b-136b; 231b-236b），所述内转子面（112a，212a）包括至少第一凹槽（121,221），第二凹槽 凹槽（122,222）和第三凹槽（123,223），其被布置成使得旋转阀可以采取至少三个不同的旋转位置，其中两个部件都被旁路，只有一个部件被连接，另一个绕过 或两个部件连接到主流。

公开(公告)号：WO2008005845A3

公开(公告)日：2008-07-31

申请号：PCT/US2007072498

申请日：2007-06-29

Applicant: WATERS INVESTMENTS LTD ,  USOWICZ JAMES E ,  BEALS PEYTON C ,  SOARES MIGUEL

Inventor： USOWICZ JAMES E ,  BEALS PEYTON C ,  SOARES MIGUEL

IPC: G01N1/00

CPC classification number: G01N30/20 ,  G01N30/22 ,  G01N2030/201 ,  G01N2030/202

Abstract: A method for processing a fluid is applied to systems that include a valve unit that has a sample-loading state and a sample-injecting state. The sample-loading state disposes a sample loop in fluidic communication with a sample conduit. The sample-injecting state disposes the sample loop in fluidic communication with a process conduit. The method involves transferring a sample through both the sample conduit and the valve unit so that a leading end of the sample exits the valve unit. After transitioning the valve unit to the sample-loading state and allowing the sample loop to decompress, at least some of the transferred sample is loaded into the sample loop. A fluid-processing instrument includes a value unit and a control unit that manages operation of the instrument. The control unit is configured, for example, to implement the above-described method.

Abstract translation: 处理流体的方法被应用于包括具有样本加载状态和样本注入状态的阀单元的系统。 样品加载状态设置与样品导管流体连通的样品环。 样品注入状态将样品环路与工艺导管流体连通。 该方法涉及将样品通过样品导管和阀单元，使得样品的前端离开阀单元。 在将阀单元转换到样品加载状态并允许样品环解压后，至少一些转移的样品被加载到样品环中。 流体处理仪器包括值单元和管理仪器操作的控制单元。 控制单元被配置为例如实施上述方法。

公开(公告)号：WO2007141718A2

公开(公告)日：2007-12-13

申请号：PCT/IB2007/052063

申请日：2007-06-01

Applicant: FIRMENICH SA ,  HAEFLIGER, Olivier

Inventor： HAEFLIGER, Olivier

IPC: G01N1/42 ,  G01N35/10 ,  G01N30/24

CPC classification number: G01N35/1097 ,  G01N1/42 ,  G01N30/20 ,  G01N30/24 ,  G01N2001/2229 ,  G01N2030/201 ,  G01N2030/202 ,  G01N2030/207

Abstract: The present invention is related to a sampling technique for volatiles and its use to concentrate and/or detect and/or separate chemical components of complex mixtures thereof that enable the automatic on-line sampling and real-time analysis of volatiles present at low concentrations, for example in the headspace.

Abstract translation: 本发明涉及用于挥发物的取样技术及其用于浓缩和/或检测和/或分离其复合混合物的化学组分的用途，其能够以低浓度存在的挥发物的自动在线取样和实时分析， 例如在顶空中。

公开(公告)号：US12025593B2

公开(公告)日：2024-07-02

申请号：US17095280

申请日：2020-11-11

Applicant: Waters Technologies Corporation

Inventor： Jason F. Hill ,  Sylvain Gilles Cormier ,  Martin Gilar

IPC: G01N30/20 ,  G01N30/10 ,  G01N30/30 ,  G01N30/34 ,  G01N30/02

CPC classification number: G01N30/20 ,  G01N30/10 ,  G01N30/34 ,  G01N2030/027 ,  G01N2030/201 ,  G01N2030/202

Abstract: Described herein are a selectable flow restriction device and a fluidic network for chromatographic sample dilution during injection. A selectable flow restriction device is used in combination with a splitter to define an adjustable splitter for separating a high-pressure solvent flow into two separate solvent flows having the same solvent composition. The first solvent flow passes to a sample manager where a sample is injected as a discrete fluidic plug at an injection valve into a flow comprising at least one solvent. The second solvent flow is merged downstream from the location of injection with the first solvent carrying the sample fluidic plug. The second solvent flow dilutes the sample plug during the mixture of the two solvent flows.

公开(公告)号：US11982652B2

公开(公告)日：2024-05-14

申请号：US17512160

申请日：2021-10-27

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Sang-Won Lee ,  Hangyeore Lee

IPC: G01N30/34 ,  B01D15/08 ,  B01D15/24 ,  B01D15/32 ,  G01N30/02 ,  G01N30/20 ,  G01N30/38 ,  G01N30/46 ,  G01N30/82 ,  G01N30/89

CPC classification number: G01N30/34 ,  B01D15/08 ,  G01N30/82 ,  G01N30/89 ,  B01D15/24 ,  B01D15/325 ,  G01N2030/027 ,  G01N2030/201 ,  G01N2030/202 ,  G01N2030/207 ,  G01N30/38 ,  G01N30/463

Abstract: Disclosed are non-contiguous sample fractionating and concatenating device and a dual online multidimensional liquid chromatography system having the same. The non-contiguous sample fractionating and concatenating device according to an embodiment of the present disclosure includes a sample supply module which supplies a sample to be analyzed, and a sample fractionation module connected to the sample supply module, and which is continuously supplied with the sample, sets a plurality of unit sample supply times obtained by equally dividing a total sample supply time during which the sample is supplied from the sample supply module, sets a plurality of unit fractionation intervals obtained by equally dividing each of the plurality of unit sample supply times, and concatenates and stores the sample supplied during corresponding unit fractionation intervals within each unit sample supply time to acquire a plurality of fractions.

公开(公告)号：US11852616B2

公开(公告)日：2023-12-26

申请号：US17143618

申请日：2021-01-07

Applicant: SAUDI ARABIAN OIL COMPANY

Inventor： Hana Matouq ,  Mohammed Sajjad Ali

IPC: G01N30/06 ,  G01N30/20 ,  G01N30/88 ,  G01N33/28 ,  G01N25/12 ,  G01N30/02 ,  G01N30/52 ,  B01D3/06 ,  E21B49/08

CPC classification number: G01N30/06 ,  G01N25/12 ,  G01N30/20 ,  G01N30/88 ,  G01N33/2823 ,  B01D3/06 ,  E21B49/088 ,  G01N2030/025 ,  G01N2030/065 ,  G01N2030/201 ,  G01N2030/522 ,  G01N2030/8854

Abstract: A system includes a phase behavior analysis unit having a housing, a heating system connected to the housing and arranged to heat an interior of the housing, a pressure cell positioned in the interior of the housing, and a three-way valve with one inlet fluidly connected to a chamber in the pressure cell and two outlets. The system also includes a gas chromatograph that is fluidly coupled to the chamber in the pressure cell via the three-way valve.

公开(公告)号：US11835496B2

公开(公告)日：2023-12-05

申请号：US17126236

申请日：2020-12-18

Applicant: Waters Technologies Corporation

Inventor： Joshua A. Burnett ,  Rose Solow ,  David A. Simpson

IPC: G01N30/24 ,  G01N30/20 ,  G01N30/36 ,  G01N30/02

CPC classification number: G01N30/24 ,  G01N30/20 ,  G01N30/36 ,  G01N2030/027 ,  G01N2030/201 ,  G01N2030/202

Abstract: A method and a fluidic network for acquiring and injecting a chromatographic sample into a chromatography system flow include a metering pump module, a sample needle, a needle seal and an injection valve. The metering pump module includes a metering pump and a pressure transducer in serial fluidic communication. When the injection valve is in a first valve state, the injection valve is configured to fluidically terminate ports of the metering pump module. When the injection valve is in a second valve state, the injection valve is configured to fluidically couple a fluidic path that includes the metering pump module and sample needle into the system flow of a chromatography system without resulting in a substantial change in the pressure of the system flow.