公开(公告)号：WO2003023815A1

公开(公告)日：2003-03-20

申请号：PCT/AU2002/001239

申请日：2002-09-10

Applicant: VARIAN AUSTRALIA PTY LTD ,  KALINITCHENKO, Iouri

Inventor： KALINITCHENKO, Iouri

IPC: H01J49/26

CPC classification number: H01J49/08

Abstract: A mass spectrometer and method of mass spectrometry in which polyatomic and doubly charged ion interferences are attenuated by establishing an electron population through which a beam of particles containing elemental sample ions and the interfering ions is passed such that the interfering ions preferentially undergo ion-electron recombination and thus dissociation to remove a significant number of the interfering ions. Means (30 or 32) for providing a population of electrons (34 or 36) in an ICP-MS (22) may comprise a magnetic field means such as an electric coil, or an electron generating device. The population of electrons has an electron number density (>10 11 cm -3 to 10 14 cm -3 ), a free electron energy (>0.01eV to

Abstract translation: 通过建立电子群减少多原子和双电荷离子干扰的质谱仪和质谱法，通过该质谱仪将含有元素样品离子和干扰离子的粒子束通过，使得干扰离子优先进行离子电子重组 并因此解离以除去大量的干扰离子。 用于在ICP-MS（22）中提供电子群体（34或36）的装置（30或32）可以包括诸如电线圈或电子产生装置的磁场装置。 电子数量的电子数密度（> 10 11 cm -3 -3 10 -10 cm -3），自由电子能量（> 0.01eV至<5eV）处于较低的区域 压力（<10Torr），使得对于通过电子群的离子的预定路径长度（1-4cm），干扰离子将优先通过解离复合过程而衰减。 离子束（40）然后通过质量分析器（42），并且通过离子检测器（44）检测已经根据其质荷比分离的离子。

公开(公告)号：EP3367422A1

公开(公告)日：2018-08-29

申请号：EP15906735.4

申请日：2015-10-23

Applicant: Shimadzu Corporation

Inventor： OSHIRO, Tomoyuki

IPC: H01J49/40

CPC classification number: H01J49/401 ,  H01J49/0009 ,  H01J49/08

Abstract: Provided is an orthogonal acceleration time-of-flight mass spectrometer in which an ion injected into an orthogonal acceleration area is accelerated in a direction orthogonal to a direction of the injection and thereby ejected into a flight space, and a mass-to-charge ratio of the ion is determined based on a time of flight of the ion. The mass spectrometer includes: an ion transport electrode (241) for transporting an ion into the orthogonal acceleration area; an orthogonal acceleration electrode (242) for orthogonally accelerating an ion injected into the orthogonal acceleration area; a flight-path-defining electrode (246) including a flight tube; a storage section (41) in which applied-voltage information which is a set of information concerning levels of voltages applied to the orthogonal acceleration electrode (241), the ion transport electrode, and the flight-path-defining electrode is stored, where an applied voltage whose level changes depending on an ion-ejection period is related to at least one of the electrodes; and a voltage supplier (44) for applying voltages to the aforementioned one of the electrodes.

公开(公告)号：EP3321952A1

公开(公告)日：2018-05-16

申请号：EP17196773.0

申请日：2017-10-17

Applicant: Bruker Daltonics, Inc.

Inventor： PARK, Melvin Andrew

IPC: H01J49/02 ,  H01J43/24

CPC classification number: H01J49/08 ,  H01J43/246 ,  H01J49/025 ,  H01J49/027 ,  H01J49/40

Abstract: The invention relates to the linear dynamic range of ion abundance measurement devices in mass spectrometers, such as time-of-flight mass spectrometers. The invention solves the problem of ion current peak saturation by producing a second ion measurement signal at an intermediate stage of amplification in a secondary electron multiplier, e.g. a signal generated between the two multichannel plates in chevron arrangement. Because saturation effects are observed only in later stages of amplification, the signal from the intermediate stage of amplification will remain linear even at high ion intensities and will remain outside saturation. In the case of a discrete dynode detector this could encompass, for example, placement of a detection grid between two dynodes near the middle of the amplification chain. The invention uses detection of the image current generated by the passing electrons.

Abstract translation: 本发明涉及质谱仪（例如飞行时间质谱仪）中的离子丰度测量装置的线性动态范围。 本发明通过在二次电子倍增器中的放大的中间阶段产生第二离子测量信号来解决离子电流峰值饱和的问题，例如， 人字形排列的两个多通道板之间产生的信号。 因为饱和效应仅在扩增的后期阶段才被观察到，所以即使在高离子强度下，来自扩增中间阶段的信号也将保持线性并且将保持在饱和之外。 在分立打拿极检测器的情况下，这可以包括例如在放大链中间附近的两个打拿极之间放置检测网格。 本发明使用检测由通过的电子产生的图像电流。

公开(公告)号：EP3179502A1

公开(公告)日：2017-06-14

申请号：EP16002630.8

申请日：2016-12-09

Applicant: Horiba Stec, Co., Ltd.

Inventor： Sasai, Kohei ,  Ikeyama, Toshihiro ,  Sakai, Toshiaki

IPC: H01J49/08

CPC classification number: H01J1/146 ,  H01J9/042 ,  H01J49/08 ,  H01J49/4215

Abstract: In order to provide a thermionic emission filament capable of ensuring a long life and improving an analysis accuracy of a mass spectrometer using the thermionic emission filament, in the thermionic emission filament (211) including a core member (211A) through which electric current flows and an electron emitting layer (211B) which is formed so as to cover a surface of the core member (211A), the electron emitting layer (211B) is configured to have denseness for substantial gas-tight integrity.

Abstract translation: 为了提供能够确保长寿命的热离子发射灯丝，并提高使用热离子发射丝的质谱仪的分析精度，在包含电流流动的芯部件（211A）的热离子发射丝（211）中， 形成为覆盖芯体（211A）的表面的电子发射层（211B），电子发射层（211B）被构造成具有基本上气密完整性的致密性。

公开(公告)号：EP2883237A1

公开(公告)日：2015-06-17

申请号：EP13829969.8

申请日：2013-08-15

Applicant: The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University

Inventor： BAROFSKY, Douglas, F. ,  VOINOV, Valery, G.

IPC: H01J49/08 ,  H01J49/26

CPC classification number: H01J49/147 ,  H01J49/0054 ,  H01J49/062 ,  H01J49/08 ,  H01J49/26

Abstract: An electron source for electron-induced dissociation in an RF-free electromagnetostatic cell for use installation in a tandem mass spectrometer is provided. An electromagnetostatic electron-induced dissociation cell may include at least one magnet having an opening disposed therein and having a longitudinal axis extending through the opening, the magnet having magnetic flux lines associated therewith, and an electron emitter having an electron emissive surface comprising a sheet, the emitter disposed about the axis at a location relative to the magnet where the electron emissive surface is substantially perpendicular to the magnetic flux lines at the electron emissive surface.

公开(公告)号：EP2819148A2

公开(公告)日：2014-12-31

申请号：EP14168583.4

申请日：2014-05-16

Applicant: Agilent Technologies, Inc.

Inventor： Prest, Harry F. ,  Kernan, Jeffrey T. ,  Wang, Mingda

IPC: H01J49/00 ,  H01J49/14

CPC classification number: H01J49/08 ,  H01J49/0031 ,  H01J49/147

Abstract: Mass spectrometry is performed utilizing an electron ionization (EI) source. The EI source ionizes a sample at different electron energies, including below and above 70 eV. The EI source may be utilized for soft ionization as well as hard ionization. The value of the electron energy may be selected so as to favor the formation of molecular ions or other ions of high analytical value. The ion source may be an axial ion source.

Abstract translation: 使用电子电离（EI）源进行质谱分析。 EI源以不同的电子能量离子化样品，包括低于70 eV以上。 EI源可用于软电离以及硬电离。 可以选择电子能量的值，以便有利于形成分子离子或具有高分析值的其它离子。 离子源可以是轴向离子源。

公开(公告)号：EP2006672A4

公开(公告)日：2012-11-21

申请号：EP07736895

申请日：2007-03-16

Applicant: RIGAKU DENKI CO LTD ,  HAMAMATSU PHOTONICS KK

Inventor： ARII TADASHI ,  TAKATA YOSHIHIRO ,  OTAKE SATOSHI ,  MATSUURA SHIGEKI

IPC: G01N27/64 ,  G01N27/62 ,  H01J49/08 ,  H01J49/10 ,  H01J49/16

CPC classification number: G01N27/64 ,  H01J49/08 ,  H01J49/147 ,  H01J49/162

Abstract: A plurality of molecular components contained in a gas are to be ionized together at the same time by the PI method. For example, a plurality of molecular components contained in a gas generated at a certain instant are accurately analyzed in real-time based on the PI method. A gas analyzer includes a gas conveyor 4 that conveys a gas generated from a sample S in a sample chamber R0 to an analysis chamber R1, an ionizer 19 that ionizes the gas, a quadrupole filter 21 that separates ions for each mass-to-charge ratio, and an ion detector 22 that detects the separated ions. The ionizer 19 has an ionizing region provided near a gas outlet of the gas conveyor 4 and a lamp 33A that applies light to the ionizing region. Since the lamp 33A emits light having an light directivity lower than that of laser light and traveling in a spreading manner, the gas having entered the ionizing region in the ionizer 19 receives light irradiation in a wide range, and a plurality of gas components therein are ionized.

公开(公告)号：EP1472713A1

公开(公告)日：2004-11-03

申请号：EP03700937.0

申请日：2003-01-27

Applicant: MICROSAIC SYSTEMS LIMITED

Inventor： SYMS, Richard

IPC: H01J49/10

CPC classification number: H01J49/147 ,  H01J49/0018 ,  H01J49/08 ,  H01J49/4215

Abstract: A method of fabricating miniature quadrupole electrostatic mass filter has been previously described. The electrodes are metallised cylinders, mounted in grooves etched in oxidised silicon substrates, which are held apart at the correct spacing by cylindrical spacer rods. This invention concerns an ion source mounted on extensions of the spacer rods, which project beyond the mass filter. The ion source consists of a cold-cathode electron emitter, which emits electrons with energies sufficient to cause impact ionisation, and electrostatic optics suitable for coupling the ion flux into the mass filter. Methods of constructing a single self-aligned electron source and a similar dual source are described. Arrangements for mounting the electron source and the ion coupling lens so that the electron and ion beams travel at right angles to one another for efficient separation are described. A method of fabricating a self-aligned one-dimensional einzel electrostatic lens from metallised cylinders mounted in the silicon substrates using etched grooves is described. A method of fabricating a-self-aligned two-dimensional einzel lens from metal plates is also described.

Abstract translation: 之前已经描述了制造微型四极静电质量过滤器的方法。 电极是金属化的圆柱体，安装在刻蚀在氧化硅衬底上的沟槽中，通过圆柱形间隔棒以正确的间隔分开。 本发明涉及一种安装在隔离杆延伸部上的离子源，其突出于质量过滤器之外。 离子源由一个冷阴极电子发射体组成，该电子发射体发射的电子的能量足以引起碰撞电离，而静电光学器件适用于将离子通量耦合到质量过滤器中。 描述了构建单个自对准电子源和类似双源的方法。 描述了用于安装电子源和离子耦合透镜的装置，以便电子和离子束彼此成直角移动以实现有效的分离。 描述了使用蚀刻凹槽由安装在硅基底中的金属化圆柱体制造自对准一维单柱静电透镜的方法。 还描述了从金属板制造自对准二维单透镜的方法。

公开(公告)号：EP0594421A1

公开(公告)日：1994-04-27

申请号：EP93308366.9

申请日：1993-10-20

Applicant: FISONS plc

Inventor： Tindall, Ian Francis ,  Amin, Vipulchandra ,  Enck, Richard S., Jr.

IPC: H01J49/08 ,  G01N23/227

CPC classification number: H01J49/08 ,  G01N23/227

Abstract: An x-ray source for use in an electron spectrometer comprises a cathode filament (23), focussing means (28,29) and a target (24) which is part of the vacuum chamber housing (10) of the electron spectrometer. The housing (10) itself acts as an anode. By forming the target as part of the vacuum housing, the spectrometer may be more economically and compactly constructed. The target may also comprise part of the energy analysing system associated with the spectrometer.

Abstract translation: 用于电子分光计的x射线源包括阴极丝（23），聚焦装置（28,29）和作为电子分光计的真空室壳体（10）的一部分的靶（24）。 壳体（10）本身用作阳极。 通过将靶材形成为真空壳体的一部分，光谱仪可以更经济和紧凑地构造。 目标还可以包括与光谱仪相关联的能量分析系统的一部分。

公开(公告)号：US20240014022A1

公开(公告)日：2024-01-11

申请号：US18255837

申请日：2021-12-03

Applicant: ISOTOPX LTD

Inventor： Damian Paul TOOTELL ,  Anthony Michael JONES

IPC: H01J49/02 ,  H01J49/04 ,  H01J49/28

CPC classification number: H01J49/022 ,  H01J49/0422 ,  H01J49/28 ,  H01J49/08

Abstract: An ion source (30) for a static gas mass spectrometer is described. The ion source (30) comprises: a source block (310) defining a volume V to receive a sample gas G; an electron source (320) in fluid communication with the source block (310) and configured to provide a flux of electrons E therein for ionising the sample gas G; a set of electrodes (330), including a first electrode (330A), disposed between the electron source (320) and the source block (310); and a controller (not shown) configured to control a voltage applied to the first electrode (330A) to attenuate the flux of the electrons E into the source block (310) during a first time period following receiving of the sample gas G in the source block (310) and to permit the flux of the electrons E into the source block (310) during a second time period following the first time period.