公开(公告)号：WO1994009699A1

公开(公告)日：1994-05-11

申请号：PCT/GB1993002223

申请日：1993-10-28

Applicant: BRITISH TECHNOLOGY GROUP LIMITED ,  BROWN, Brian, Hilton ,  BARBER, David, Charles

Inventor： BRITISH TECHNOLOGY GROUP LIMITED

IPC: A61B05/05

CPC classification number: A61B5/0536

Abstract: A method of investigation of a body comprises applying interrogatory electrical signals at different frequencies to the body, obtaining first signals representing first electrical impedance measurements at the different frequencies, obtaining second signals representing subsequent second electrical impedance measurements at the different frequencies after a change in the internal state of the body and selectively determining characteristics of part of said body in response to the first and second signals at the different frequencies. The invention has application in electrical impedance tomography techniques where the different frequency behaviour of different parts of the body associated with temporal changes can be used to improve organ resolution and tissue differentiation.

Abstract translation: 身体的调查方法包括以不同的频率向身体施加询问电信号，获得表示在不同频率下的第一电阻抗测量的第一信号，获得代表在不同频率下的不同频率的后续第二电阻抗测量的第二信号 身体的内部状态，并且响应于在不同频率的第一和第二信号选择性地确定所述身体的一部分的特性。 本发明应用于电阻抗层析成像技术，其中与时间变化相关的身体不同部位的不同频率行为可用于改善器官分辨率和组织分化。

公开(公告)号：WO1994003108A1

公开(公告)日：1994-02-17

申请号：PCT/US1993007205

申请日：1993-07-30

Applicant: SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH

Inventor： SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH ,  DAGHIGHIAN, Farhad ,  MIODOWNICK, Saul ,  SHENDEROV, Peter ,  ESHAGHIAN, Behzad

IPC: A61B05/05

CPC classification number: G01T1/161 ,  A61B6/4258

Abstract: An imaging apparatus with a flexible light guide which a surgeon can easily manipulate within the patient to control the field of view. Specifically, a scintillator (200) receives radiation rays and converts these radiation rays into light signals at a position inside the body. A flexible bundle of optical fibers (205) optically connected at the scintillator (200) channels the light signals from the scintillator (200) to a position sensitive light signal detector (210) located outside the body. The position sensitive light signal detector creates a digital signal to relay the position information about the detected event to a computer (235) which accumulates these digital signals, converts these digital signals into images and displays the images.

Abstract translation: 具有柔性光导的成像装置，外科医生可以容易地在患者内操纵以控制视野。 具体地，闪烁体（200）接收辐射线并将这些辐射线转换成在身体内的位置处的光信号。 在闪烁体（200）处光学连接的柔性光纤束（205）将来自闪烁体（200）的光信号传送到位于身体外部的位置敏感光信号检测器（210）。 位置敏感光信号检测器创建一个数字信号，将有关检测到的事件的位置信息中继到累积这些数字信号的计算机（235），将这些数字信号转换成图像并显示图像。

公开(公告)号：WO1992013485A1

公开(公告)日：1992-08-20

申请号：PCT/US1992000711

申请日：1992-01-30

Applicant: BRIGHAM AND WOMEN'S HOSPITAL

Inventor： BRIGHAM AND WOMEN'S HOSPITAL ,  SCHELTINGA, Marc, R. ,  WILMORE, Douglas, W.

IPC: A61B05/05

CPC classification number: A61B5/4869 ,  A61B5/0535 ,  A61B5/0537 ,  A61B5/4872

Abstract: First and second pairs of electrodes (40, 50) are connected to a bioelectrical impedance measuring device (22). The first pair of electrodes are then attached to a subject's body to introduce an electrical current in the subject's body. The second pair of electrodes (50) are attached to the body in proximity with the elbow and the knee joint of the subject's body. The second pair of electrodes detects the impedance in the subject's body when the electrical current flows therein by the first pair of electrodes (40). The bioelectrical impedance measurement device (22) measures the impedance detected by the second pair of electrodes (50).

公开(公告)号：WO1991002485A1

公开(公告)日：1991-03-07

申请号：PCT/US1990004571

申请日：1990-08-14

Applicant: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW

Inventor： RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW ,  BRODERICK, Patrica, A.

IPC: A61B05/05

CPC classification number: G01N33/48707

Abstract: This invention relates to a microelectrode comprising graphite, oil and, additionally, a compound selected from the group of lipids, glycolipids, lipoproteins, fatty acids, fatty acid derivatives, any water insoluble species and perfluorosulfonated compounds and salts thereof. This invention also relates to a method for using the microelectrode, a device that may be employed with the microelectrode, a method for making the microelectrode, and a method for using the device with the microelectrode.

Abstract translation: 本发明涉及包含石墨，油和另外选自脂质，糖脂，脂蛋白，脂肪酸，脂肪酸衍生物，任何水不溶性物质和全氟磺化化合物及其盐的化合物的微电极。 本发明还涉及使用微电极的方法，可与微电极一起使用的装置，微电极的制造方法以及使用该微电极的方法。

公开(公告)号：WO1990015572A1

公开(公告)日：1990-12-27

申请号：PCT/US1990003424

申请日：1990-06-15

Applicant: SYNETICS MEDICAL, INC.

Inventor： SYNETICS MEDICAL, INC. ,  BOMBECK, C., Thomas, IV

IPC: A61B05/05

CPC classification number: A61B5/14542 ,  A61B5/037 ,  A61B5/14539 ,  A61B5/1473 ,  A61B5/6853

Abstract: An intraesophageal catheter (10) comprising a tubular body (12), a pH sensor (14) extending through the interior of the tubular body (12) for pH measurement, and a balloon inflation pressure sensor (16) communicating with the interior of the tubular body. The tubular body (12) is comprised of clear polyvinyl chloride material and has a radiopaque stripe (22) extending longitudinally along the tubular body. A plurality of circumferential gradations (24) are marked on the tubular body. The pH sensor has a head portion (30) fastened to the end of the tubular body and a conductor (32) connected to and extending from the head portion to the other end of the tubular body. The head portion is comprised of a polycarbonate material having a smooth surface. The balloon inflation pressure sensor is a balloon (50) that is positioned on the tubular body apart from the head portion of the pH sensor. A balloon inflation channel (40) extends through the interior of the tubular body and communicates with the balloon molded to the exterior surface of the tubular body.

公开(公告)号：WO1990000367A1

公开(公告)日：1990-01-25

申请号：PCT/US1989003009

申请日：1989-07-11

Applicant: BOMED MEDICAL MANUFACTURING, LTD.

Inventor： BOMED MEDICAL MANUFACTURING, LTD. ,  SRAMEK, Bohumir

IPC: A61B05/05

CPC classification number: A61B5/0535 ,  A61B5/021 ,  A61B5/412

Abstract: A therapeutic system provides a clinician with an appropriate course of treatment for a patient whose cardiovascular system is operating outside the normal range of values for the left cardiac work index (LCWI) and the systemic vascular resistance index (SVRI). The left cardiac work index and the systemic vascular resistance index are calculated from the cardiac index (CI) and mean arterial blood pressure (MAP) and are displayed as relative values so that the clinician can readily determine which of the vascular parameters are outside the normal range. Preferably, the cardiac index and the other cardiac parameters are measured by an electrical bioimpedance monitor (104) that provides continuous dynamic measurement of the parameters. The left cardiac work index and the systemic vascular resistance index are calculated by a personal computer (140) that displays the calculated parameters in an easily discernible manner.

Abstract translation: 治疗系统为临床医生提供适合于心血管系统在左心功能指数（LCWI）和全身血管阻力指数（SVRI）的正常范围范围以外操作的患者的治疗过程。 从心脏指数（CI）和平均动脉血压（MAP）计算左心功能指数和全身血管阻力指数，并显示为相对值，使临床医生可以容易地确定哪个血管参数在正常范围之外 范围。 优选地，通过提供参数的连续动态测量的电生物阻抗监测器（104）来测量心脏指数和其它心脏参数。 左心功能指数和全身血管阻力指数由个人计算机（140）计算，其以容易辨别的方式显示所计算的参数。

公开(公告)号：WO1989012422A1

公开(公告)日：1989-12-28

申请号：PCT/JP1989000589

申请日：1989-06-12

Applicant: OTSUKA ELECTRONICS CO., LTD. ,  TAKAMURA, Susumu ,  NAKAMURA, Takashi ,  OKAWAUCHI, Makoto ,  TODA, Harumi ,  KANKI, Ichiro ,  YOSHIDA, Minoru ,  IMOTO, Toshiyuki ,  NEGAYAMA, Naomi ,  OKA, Koichi

Inventor： OTSUKA ELECTRONICS CO., LTD.

IPC: A61B05/05

CPC classification number: G01R33/30 ,  A61B5/055 ,  G01R33/34007 ,  G01R33/34053 ,  G01R33/341 ,  G01R33/465 ,  Y10T436/24

Abstract: For NMR measurements, a coil (7) for receiving free induction signals of NMR is brought into contact with or close to one side of a living tissue (1) placed in a perfusate (4) while the receiving coil (7) is kept totally or partially out of contact with the perfusate (4). According to the above measuring method in which the receiving coil (7) is somewhat out of contact with the perfusate (4), electromagnetic effects due to a change in the perfusate (4) are decreased so that free induction signals are not buried in the noise, making it possible to take measurement maintaining favorable sensitivity. Even in the case of a large organ, the receiving coil (7) is brought into contact with or close to one surface of the organ to take measurement. Therefore, signals are obtained only from a region of uniform magnetic field, and free induction signals of high resolution is obtained.

Abstract translation: 对于NMR测量，用于接收NMR的自由感应信号的线圈（7）与放置在灌注液（4）中的活组织（1）的一侧接触或接近，同时接收线圈（7）保持完全 或部分不与灌注液（4）接触。 根据上述接收线圈（7）与灌注液（4）有些不接触的测量方法，由于灌注液（4）的变化引起的电磁效应降低，使得自由感应信号不被埋在 噪音，使测量维持良好的灵敏度成为可能。 即使在大器官的情况下，接收线圈（7）与器官的一个表面接触或接近，以进行测量。 因此，仅从均匀磁场的区域获得信号，并且获得高分辨率的自由感应信号。

公开(公告)号：WO1989010722A1

公开(公告)日：1989-11-16

申请号：PCT/US1989001881

申请日：1989-05-03

Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM

Inventor： BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM ,  CHAVARRIA, Lazaro ,  MORGAN, Tommie, J.

IPC: A61B05/05

CPC classification number: A61B6/501 ,  A61B5/0555 ,  A61B5/4528 ,  G01R33/28

Abstract: The present invention relates to a portable head positioning system for the establishment and measurement of variety of different head orientations for the purposes of magnetic resonance imaging. The present system comprises a head engagement assembly and a mouthpiece or orientation component which cooperate to enable reproducible imaging.

公开(公告)号：WO1989007417A1

公开(公告)日：1989-08-24

申请号：PCT/JP1989000162

申请日：1989-02-17

Applicant: MOTOYAMA, Hiroshi ,  KOBAYASHI, Keisuke ,  AKASAKA, Fumio ,  ITAGAKI, Yoshiko

IPC: A61B05/05

CPC classification number: A61B5/0531 ,  A61B5/4561 ,  A61B2018/00875

Abstract: An apparatus for measuring data of a living body in which rectangular voltage pulses are applied to at least a pair of electrodes attached to the surface of a living body, a current waveform parameter that represents an equation for approximating the waveform of a transient current is found by analysis from the transient current that flows across the electrodes, and an equivalent circuit parameter that represents an electric equivalent circuit between the electrodes and/or a parameter of transient characteristics representing the feature of the transient current are calculated from the current waveform parameter. At least one of these parameters is used as the data of a living body and abnormal condition in the living body is detected based on this data.

公开(公告)号：WO1988007349A1

公开(公告)日：1988-10-06

申请号：PCT/US1988000893

申请日：1988-03-21

Applicant: FONAR CORPORATION

Inventor： FONAR CORPORATION ,  MORRONE, Terry ,  DWORKIN, Jay, S. ,  GREENHALGH, John, F.

IPC: A61B05/05

CPC classification number: G01R33/5635 ,  A61B5/0263 ,  A61B5/7285 ,  G01R33/56308

Abstract: An object (50) incorporating stationary matter and moving matter such as blood is imaged by applying a series of NMR signal generation suquences. A first sequence (C1, C10, C100, C101) generates an NMR signal and a second sequence (C2, C20, C200, C202) generates an NMR signal of opposite phase. The second sequence may include an RF excitation signal (78) of opposite phase to the corresponding RF excitation signal (78) in the first sequence. NMR signals resulting from these two sequences are added to form composite signals. Components of the NMR signals produced by stationary matter in the object cancel one another during addition because of the oppositely phased excitation signals, whereas components of the NMR signals produced by the moving matter or blood are affected differently by velocity and hence do not cancel one another. Different velocity effects in the two sequences may be created by synchronizing the sequences to different phases of a velocity waveform (56) of the moving matter.

Abstract translation: 通过应用一系列NMR信号产生成像对包含静止物质和诸如血液的运动物质的物体（50）进行成像。 第一序列（C1，C10，C100，C101）产生NMR信号，第二序列（C2，C20，C200，C202）产生相反相的NMR信号。 第二序列可以包括与第一序列中相应的RF激励信号（78）相反的RF激励信号（78）。 加入由这两个序列产生的NMR信号以形成复合信号。 由于相反的激励信号，由物体中的固体物质产生的NMR信号的组分彼此抵消，而由移动物质或血液产生的NMR信号的分量受速度的影响不同，因此不会彼此抵消 。 可以通过将序列同步到运动物质的速度波形（56）的不同相位来产生两个序列中的不同速度效应。