公开(公告)号：JP2009084277A

公开(公告)日：2009-04-23

申请号：JP2008234662

申请日：2008-09-12

Applicant: Shizuoka Prefecture ,  Sunstar Inc ,  サンスター株式会社 ,  静岡県

Inventor： FUJISAWA KOICHI ,  OHARA TAKESHI ,  KANAMORI TAKEYUKI ,  OTA YOJIRO

IPC: A61K8/44 ,  A61K8/46 ,  A61Q11/00

Abstract: PROBLEM TO BE SOLVED: To provide a low stimulating dentifrice composition while formulating laurylsulfate in order to give moderate foamability.
SOLUTION: (A) 0.2-0.7 wt.% of laurylsulfate and (B) 0.2-0.7 wt.% of fatty acid amidopropylbetaine are formulated at a compounding ratio of (A):(B)=1:0.5-1:2, thereby the dentifrice composition with moderate foamability and reduced stimulation to an oral cavity is made.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：为了提供适度的起泡性，提供低刺激性洁齿剂组合物同时配制月桂基硫酸盐。 解决方案：（A）0.2-0.7重量％的月桂基硫酸盐和（B）0.2-0.7重量％的脂肪酸​​酰胺丙基甜菜碱以（A）：（B）= 1：0.5-1的配混比配制 ：2，从而制成具有适度发泡性和减少对口腔刺激的洁齿剂组合物。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2009077908A

公开(公告)日：2009-04-16

申请号：JP2007249212

申请日：2007-09-26

Applicant: Fuji Ceramics:Kk ,  Os Technology Inc ,  Shizuoka Prefecture ,  株式会社オーエステクノロジー ,  株式会社富士セラミックス ,  静岡県

Inventor： NAKAYAMA HIROSHI ,  MANO TAKESHI ,  OZAKI KENZO ,  FUKUSHIMA TOSHIHIRO

IPC: A61B5/11 ,  A61B5/00 ,  A61G7/05 ,  A61G12/00 ,  G08B21/02 ,  G08B25/10

Abstract: PROBLEM TO BE SOLVED: To provide a care receiver movement detector and a care receiver movement detecting method, precisely detecting a movement with the risk of leaving a bed, tumbling and falling timely without giving discomfort to a care receiver, thereby preventing an accident such as a care receiver's carelessly tumbling and falling from a caring bed.
SOLUTION: This detector includes an infrared sensor installed in a preset predetermined place for detecting an infrared ray output from the care receiver, a Fresnel lens fitted to the infrared sensor; a care receiver movement discriminating means for discriminating the movement of the care receiver by inputting an output signal of the infrared sensor and analyzing the input in the relationship with a preset threshold; and an informing means for giving information to the care receiver according to the discrimination of the care receiver movement discriminating means if necessary.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：为了提供一种护理接收器运动检测器和护理接收器运动检测方法，精确地检测具有离开床的风险的运动，及时滚动和下降，而不会给护理接收器带来不适，从而防止 事故，如护理接收人不小心翻滚，从一张床上掉下来。

解决方案：该检测器包括安装在预设预定位置的红外传感器，用于检测从护理接收器输出的红外线;安装在红外线传感器上的菲涅尔透镜; 护理接收器移动识别装置，用于通过输入红外传感器的输出信号并以与预设阈值的关系分析输入来识别护理接收器的移动; 以及如果需要，根据护理接收者移动识别装置的区分向护理接收者提供信息的通知装置。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2009017801A

公开(公告)日：2009-01-29

申请号：JP2007181289

申请日：2007-07-10

Applicant: Sapporo Breweries Ltd ,  Shizuoka Prefecture ,  サッポロビール株式会社 ,  静岡県

Inventor： YAMASHITA SHINJI ,  KURIHARA TOSHIO ,  KATO HISAO ,  MITANI MASARU ,  IKETANI MORIJI

IPC: A23K1/16 ,  A23K1/18

Abstract: PROBLEM TO BE SOLVED: To provide a new application of hop tissue or its extract, as a yolk color brightener or a haugh unit improving agent of an egg. SOLUTION: This yolk color brightener is made from hop tissue or its cold water extract. Yolk has a color having reduced reddishness and shows a yellowish color by giving hens the yolk color brightener. A feed additive which contains the yolk color brightener is also provided. The feed additive is favorably used for rearing egg-laying poultry. COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供啤酒花组织或其提取物的新应用，作为蛋黄色增白剂或卵的高单位改良剂。

解决方案：该蛋黄色增白剂由啤酒花组织或其冷水提取物制成。 蛋黄具有减少红色的颜色，并通过给母鸡蛋黄色增白剂显示淡黄色。 还提供了含有蛋黄增白剂的饲料添加剂。 饲料添加剂有利地用于养殖产蛋家禽。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2008295415A

公开(公告)日：2008-12-11

申请号：JP2007147525

申请日：2007-06-01

Applicant: Shizuoka Prefecture ,  静岡県

Inventor： AKIYAMA YASUTO

IPC: C12N15/09 ,  C12P21/08 ,  C12Q1/68

Abstract: PROBLEM TO BE SOLVED: To position the genetic analysis of mRNA originated from one immunized cell as a target of future research and development, and to provide a technique for efficiently analyzing and identifying the sequence of a specific immunity-related gene, a technique for producing an antibody originated from one B cell, or the like.
SOLUTION: This method for analyzing and identifying an antibody gene originated from one B cell includes: collecting peripheral blood mononucleosis obtained from a cancer patient whose immune reaction against a cancer-specific antigen peptide is confirmed by the administration of a dendritic cell vaccine treated with the cancer-specific antigen peptide; labeling B cells in the peripheral blood mononucleosis with a labeled cancer-specific antigen peptide and a human antibody; individually collecting the B cells each expressing an antibody on the cell membrane; extracting the whole RNA; synthesizing cDNA by a reverse transcription; amplifying a gene fragment by a PCR reaction using the synthesized cDNA as a template; and then analyzing and determining the base sequence of the amplified gene fragment.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：将来自一个免疫细胞的mRNA的遗传分析定位为未来研究和开发的目标，并提供用于有效分析和鉴定特异性免疫相关基因的序列的技术， 用于产生源于一个B细胞的抗体的技术等。 解决方案：用于分析和鉴定源自一个B细胞的抗体基因的方法包括：收集从癌症患者获得的外周血单核细胞增多症，其通过施用树突状细胞疫苗确认对癌症特异性抗原肽的免疫反应 用癌症特异性抗原肽治疗; 用标记的癌特异性抗原肽和人抗体标记外周血单核细胞增多症中的B细胞; 单独收集在细胞膜上各自表达抗体的B细胞; 提取整个RNA; 通过逆转录合成cDNA; 使用合成的cDNA作为模板通过PCR反应扩增基因片段; 然后分析和确定扩增的基因片段的碱基序列。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2008272575A

公开(公告)日：2008-11-13

申请号：JP2007005311

申请日：2007-01-15

Applicant: Karuto Kk ,  Shizuoka Prefecture ,  カルト株式会社 ,  静岡県

Inventor： OKAMOTO TETSUSHI ,  MATSUMOTO YUTAKA ,  SUZUKI MITSUAKI ,  YAMAMOTO SUMIO

IPC: B09C1/02 ,  A62D3/30 ,  A62D3/38 ,  A62D101/22 ,  B01J4/00 ,  B09B3/00 ,  B09C1/08

Abstract: PROBLEM TO BE SOLVED: To provide an apparatus for decontaminating polluted soil, which enables an efficient and effective decontamination of the polluted soil by utilizing laconically a gas for decontamination and water.
SOLUTION: Apparatuses 3a, 3b, and 3c for supplying the gas for decontamination is provided to supply the gas for decontamination containing ozone as a composition gas in the ground E through pipes for decontamination 13a, 13b, and 13c passing through a hole perforated in the ground surface F. A water supply device 5 to supply water in the ground E through the pipes for decontamination 13a, 13b, and 13c is provided. A control device 7 is provided, the device controlling the timing of supplying the gas for decontamination and water such that a predetermined supply time of the gas for decontamination to supply the gas for decontamination by the apparatuses 3a, 3b, and 3c for supplying the gas for decontamination and a predetermined water supply time to supply water by the water supply device 5 be repeated alternately.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供一种用于净化污染土壤的设备，其通过利用天然气去除污染和水来实现对污染土壤的有效和有效的去污。 提供用于供给净化用气体的装置3a，3b，3c供给用于通过通过通孔的净化管13a，13b，13c的含臭氧作为组成气体的废气进行净化处理 在地面F上穿孔。提供了一种供水装置5，其通过用于净化的管道13a，13b和13c向地面E供水。 设置控制装置7，该装置控制供给用于净化的气体的定时和水，以使得用于净化的气体的预定供给时间供应用于供给气体的装置3a，3b和3c的用于净化的气体 用于净化，并且由供水装置5供给水的预定供水时间被交替地重复。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2008249587A

公开(公告)日：2008-10-16

申请号：JP2007093031

申请日：2007-03-30

Applicant: Shizuoka Prefecture ,  静岡県

Inventor： MOCHIZUKI TORU ,  OSHIMA KEIICHI ,  OGURA SHUNICHIRO

IPC: G01N33/574 ,  C07K14/435 ,  C12Q1/68 ,  G01N33/15 ,  G01N33/50

Abstract: PROBLEM TO BE SOLVED: To provide a new tumor marker allowing early diagnosis of stomach cancer, small cell lung cancer, non-small cell lung cancer, etc.
SOLUTION: The expressed amount of calmodulin is measured in a biological specimen taken from a human. In cases where the expression of calmodulin is detected, it is determined that an object person is highly likely to have cancer. In measuring the expressed amount of calmodulin, a primer set or a probe, or their labeled substances are suitably used for detecting the existence of an anti-calmodulin monoclonal antibody or mRNA of calmodulin. Further, human tumor cell strain is cultivated in the presence of a test substance to measure the expressed amount of calmodulin in cell culture supernatant, and comparison/evaluation is made with a case in the non-presence of the test substance, making it possible to screen depressant/cure for tumor.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供允许胃癌，小细胞肺癌，非小细胞肺癌等的早期诊断的新的肿瘤标志物。解决方案：钙调素的表达量在生物学 标本取自人类。 在检测到钙调蛋白的表达的情况下，确定对象人很可能患有癌症。 在测定钙调蛋白的表达量时，引物组或探针或其标记物质适合用于检测抗钙调蛋白单克隆抗体或钙调蛋白的mRNA的存在。 此外，在测试物质的存在下培养人肿瘤细胞株，以测量细胞培养上清液中钙调蛋白的表达量，并且在不存在测试物质的情况下进行比较/评估，使得可以 屏障抑制/治愈肿瘤。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2008249524A

公开(公告)日：2008-10-16

申请号：JP2007091988

申请日：2007-03-30

Applicant: Shizuoka Prefecture ,  静岡県

Inventor： MOCHIZUKI TORU ,  OSHIMA KEIICHI ,  OGURA SHUNICHIRO

IPC: G01N33/574 ,  C12N15/09 ,  C12Q1/68 ,  G01N33/15 ,  G01N33/50

Abstract: PROBLEM TO BE SOLVED: To provide a new tumor marker allowing early diagnosis of stomach cancer, small cell lung cancer, non-small cell lung cancer, etc.
SOLUTION: The expressed amount of ubiquitin is measured in a biological specimen taken from a human. In cases where the expression of ubiquitin is detected, it is determined that an object person is highly likely to have cancer. In measuring the expressed amount of ubiquitin, a primer set or a probe, or their labeled substances are suitably used for detecting the existence of an anti-ubiquitin monoclonal antibody or mRNA of ubiquitin. Further, human tumor cell strain is cultivated in the presence of a test substance to measure the expressed amount of ubiquitin in cell culture supernatant, and comparison/evaluation is made with a case in the non-presence of the test substance, making it possible to screen depressant/cure for tumor.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供允许胃癌，小细胞肺癌，非小细胞肺癌等的早期诊断的新的肿瘤标志物。解决方案：在生物学中测量泛素的表达量 标本取自人类。 在检测到泛蛋白的表达的情况下，确定对象人很可能患有癌症。 在测量泛素的表达量时，引物组或探针或其标记物质适用于检测泛素泛素单克隆抗体或泛素mRNA的存在。 此外，在测试物质存在下培养人肿瘤细胞株，以测量细胞培养上清液中泛素的表达量，并且在不存在测试物质的情况下进行比较/评价，使得可以 屏障抑制/治愈肿瘤。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2008245601A

公开(公告)日：2008-10-16

申请号：JP2007092968

申请日：2007-03-30

Applicant: Shizuoka Prefecture ,  静岡県

Inventor： AKIYAMA YASUTO ,  MARUYAMA KOJI

IPC: C12N15/09 ,  C07K16/00 ,  C12N1/21 ,  C12P21/08

Abstract: PROBLEM TO BE SOLVED: To provide a method for efficiently mass-preparing human antibody ScFv fragments. SOLUTION: The method comprises the following processes: A gene fragment encoding an antibody heavy chain-variable domain (heavy chain fragment) and a gene fragment encoding an antibody light chain-variable domain (light chain fragment) are amplified respectively by PCR technique. The resulting heavy chain fragments and light chain fragments are further amplified into heavy chain conjugate fragments each comprising a heavy chain fragment-heavy chain linker sequence-restriction enzyme Xbal recognition sequence and into light chain conjugate fragments each comprising a restriction enzyme Nhel recognition sequence-light chain linker sequence-light chain fragment, respectively. The heavy chain conjugate fragments and the light chain conjugate fragments are digested by restriction enzyme Xbal and restriction enzyme Nhel, respectively, and then joined each other by ligation. The resulting ligation product is digested by the restriction enzyme Xbal and restriction enzyme Nhel and then amplified into the objective human ScFv fragments each comprising a heavy chain fragment-linker sequence-light chain fragment. COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 待解决的问题：提供有效地批量制备人抗体ScFv片段的方法。 解决方案：该方法包括以下过程：编码抗体重链可变结构域（重链片段）的基因片段和编码抗体轻链可变区（轻链片段）的基因片段分别通过PCR扩增 技术。 将所得重链片段和轻链片段进一步扩增至重链缀合物片段，每个重链结合片段均包含重链片段 - 重链接头序列限制酶XbaI识别序列，并分别转入轻链共轭片段，每个轻链共轭片段均含有限制酶Nhel识别序列 链接序列轻链片段。 重链结合片段和轻链共轭片段分别用限制性内切酶XbaI和限制酶NheI消化，然后通过连接相互连接。 所得的连接产物被限制酶XbaI和限制酶NheI消化，然后扩增到每个包含重链片段 - 接头序列 - 轻链片段的目标人ScFv片段。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2008237161A

公开(公告)日：2008-10-09

申请号：JP2007085289

申请日：2007-03-28

Applicant: Shizuoka Prefecture ,  静岡県

Inventor： OISHI NAOKI

IPC: A01G7/00 ,  A01G31/00

CPC classification number: Y02P60/216

Abstract: PROBLEM TO BE SOLVED: To provide a method for determining the growth stage of a plant, which enables accurate determination of the growth stage of a plant. SOLUTION: The method for determining the growth stage of a plant includes setting scattering-light sensors 1 each composed of a black light-shielding frame 2 where only one vertical surface of a cubic box body is made open, and a silicon photodiode 3 set up inside the light-shielding frame 2 in a posture of making a light-receiving surface face to the opening of the light-shielding frame 2, at two portions on the inside of a plant group P and the outside of the plant group P respectively, in a state where the respective receiving surfaces face to the north direction, measuring an output difference ΔP of both of the scattering light sensors 1, 1 with a measurement means 7 so as to determine the growth stage of the plant based on the measurement result. COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供一种用于确定植物生长阶段的方法，其能够准确测定植物的生长阶段。 解决方案：用于确定植物的生长阶段的方法包括设置散射光传感器1，每个散射光传感器1由仅形成立方体箱体的一个垂直表面的黑色遮光框架2和硅光电二极管 3以遮光框架2的开口形成受光面的姿势设置在遮光框架2的内部，在植物群P的内侧的两部分和植物群体的外侧 P分别在各接收面朝向北方向的状态下，用测定单元7测定两个散射光传感器1,1的输出差ΔP，以便基于该测量单元7确定设备的生长阶段 测量结果。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2008233753A

公开(公告)日：2008-10-02

申请号：JP2007076396

申请日：2007-03-23

Applicant: Inoac Corp ,  Shizuoka Prefecture ,  株式会社イノアックコーポレーション ,  静岡県

Inventor： UENO TAKAYASU ,  KINO NAOKI ,  MAKINO HIROSHI ,  SUZUKI YASUHIRO

IPC: G10K11/16 ,  E01F8/00 ,  E04B1/86

Abstract: PROBLEM TO BE SOLVED: To provide a sound absorbing structure which can have desired sound absorption characteristics with simple constitution and can be reduced in manufacturing cost.
SOLUTION: The sound absorbing structure according to the present invention includes a lattice-shaped structure and a sheet material installed on a top surface of the lattice-shaped structure. Consequently, the sound absorbing structure having desired sound absorption characteristics with simple constitution can be provided and the manufacturing cost is made low. Further, the lattice-shaped structure may be a single structure which is uniform in height or a combination of a plurality of structures which are different in height.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供一种能够以简单的结构具有期望的吸声特性并且可以降低制造成本的吸音结构。 解决方案：根据本发明的吸音结构包括格状结构和安装在格子状结构的顶表面上的片材。 因此，可以提供具有简单结构的期望的吸音特性的吸声结构，并且制造成本降低。 此外，格子状结构可以是高度均匀的单一结构或高度不同的多个结构的组合。 版权所有（C）2009，JPO＆INPIT