Aerosol generator
    131.
    发明授权

    公开(公告)号:US10322432B2

    公开(公告)日:2019-06-18

    申请号:US15476242

    申请日:2017-03-31

    Abstract: An aerosol generator (100) has a vibratable plate (1) with apertures therein and an annular piezo (2) which causes movement of the vibratable plate (1). An annular support member (3) supports the piezo (2) and the vibratable plate (1). A first electrical power conducting pin (10) engages directly with a first, top, surface of the piezo (2). A second electrical power conducting pin (11) indirectly conducts electrical power to a second surface of the piezo (2), by contacting an extension tab (103) of the support member (20), also on its top side. There is a film of cured epoxy adhesive on the tab (103), providing excellent gripping force between the pin (11) and the support (3). The aerosol generator (100) avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the on the same lateral and top side of the piezo and support member. The pins may have multi-point tips (50) for particularly effective electrical contact.

    Method for producing an aperture plate

    公开(公告)号:US10279357B2

    公开(公告)日:2019-05-07

    申请号:US14719036

    申请日:2015-05-21

    Abstract: An aperture plate is manufactured by plating metal around a mask of resist columns having a desired size, pitch, and profile, which yields a wafer about 60 μm thickness. This is approximately the full desired target aperture plate thickness. The plating is continued so that the metal overlies the top surfaces of the columns until the desired apertures are achieved. This needs only one masking/plating cycle to achieve the desired plate thickness. Also, the plate has passageways formed beneath the apertures, formed as an integral part of the method, by mask material removal. These are suitable for entrainment of aerosolized droplets exiting the apertures.

    Aerosol delivery system
    133.
    发明授权

    公开(公告)号:US10092712B2

    公开(公告)日:2018-10-09

    申请号:US14530173

    申请日:2014-10-31

    Abstract: A system for delivery of aerosol therapy to spontaneously breathing patients comprises a housing which defines a chamber. The housing has a base, a top and a main body extending between the base and the top. An ambient air inlet is located adjacent to the base and is normally closed by an inlet valve. The housing also has a patient port for receiving a mouthpiece or a face mask. The mouthpiece has an exhaust outlet closed by an exhaust valve. Similarly, the face mask has an exhaust outlet closed by an exhaust valve. Exhaled air is exhausted through the valves and to prevent recirculation through the chamber which would adversely affect dose efficiencies. The housing also has an aerosol port for receiving a vibrating mesh aerosol generating device. The aerosol port is located in a side of the main body of the housing for delivery of aerosol into the chamber between the inlet valve and the patient port. A boss extends upwardly from the base and is spaced-apart inwardly of the main body of the housing to define a reception space or well.

    AEROSOL GENERATION
    134.
    发明申请
    AEROSOL GENERATION 审中-公开

    公开(公告)号:US20180169691A1

    公开(公告)日:2018-06-21

    申请号:US15578923

    申请日:2016-06-10

    Abstract: A method for aerosolising a liquid comprises the steps of:—providing an aperture plate having at least 100 outlet holes per mm2; delivering liquid to the aperture plate; and vibrating the aperture plate to produce an aerosol. The viscosity of the liquid is in the range of from 1 to 15 cP and the surface tension of the liquid is in the range of from 72 to 0.5 mN/m. The output rate of the generated aerosol is greater than 0.01 mL/min.

    AEROSOL GENERATOR
    135.
    发明申请
    AEROSOL GENERATOR 审中-公开

    公开(公告)号:US20170203321A1

    公开(公告)日:2017-07-20

    申请号:US15476461

    申请日:2017-03-31

    CPC classification number: B05B17/0646 A61M11/001 A61M11/005 A61M15/0085

    Abstract: An aerosol generator (100) has a vibratable plate (1) with apertures therein and an annular piezo (2) which causes movement of the vibratable plate (1). An annular support member (3) supports the piezo (2) and the vibratable plate (1). A first electrical power conducting pin (10) engages directly with a first, top, surface of the piezo (2). A second electrical power conducting pin (11) indirectly conducts electrical power to a second surface of the piezo (2), by contacting an extension tab (103) of the support member (20), also on its top side. There is a film of cured epoxy adhesive on the tab (103), providing excellent gripping force between the pin (11) and the support (3). The aerosol generator (100) avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the on the same lateral and top side of the piezo and support member. The pins may have multi-point tips (50) for particularly effective electrical contact.

    AEROSOL DELIVERY SYSTEM WITH HUMIDIFICATION
    136.
    发明申请

    公开(公告)号:US20170182266A1

    公开(公告)日:2017-06-29

    申请号:US15300513

    申请日:2015-06-10

    Inventor: Patrick Power

    Abstract: An aerosol delivery system has a nebulizer and a humidifier providing a gas flow to the nebulizer. A controller varies humidity level of the gas flow to the nebulizer so that if the nebulizer is not operating it has about 100% humidity and it is operating the value is less to allow for the humidification effect of the nebulizer. The control may be achieved by dynamically varying proportions of flow through a dry branch and a humidification branch.

    AEROSOL GENERATOR
    137.
    发明申请
    AEROSOL GENERATOR 审中-公开
    航空发电机

    公开(公告)号:US20170043106A1

    公开(公告)日:2017-02-16

    申请号:US15110055

    申请日:2016-03-23

    Abstract: A liquid reservoir (100) of a nebulizer has a funnel portion (102) with ribs (103, 104) extending downwardly along a side wall towards a reservoir outlet (105). The ribs (103, 104) prevent the formation of air bubbles between the aperture plate and medication as any trapped air will be expelled along the geometry formed by the rib or groove and reservoir wall. Bubble formation is therefore prevented with only modification of the wall internal surface configuration of the reservoir.

    Abstract translation: 喷雾器的液体储存器(100)具有漏斗部分(102),肋部(103,104)沿着侧壁朝着储存器出口(105)向下延伸。 肋(103,104)防止在孔板和药物之间形成气泡,因为任何被捕获的空气将沿着由肋或槽和储存器壁形成的几何形状排出。 因此,仅通过改变储存器的壁内表面结构来防止气泡形成。

    PHOTODEFINED APERTURE PLATE AND METHOD FOR PRODUCING THE SAME
    138.
    发明申请
    PHOTODEFINED APERTURE PLATE AND METHOD FOR PRODUCING THE SAME 审中-公开
    光电孔板及其制造方法

    公开(公告)号:US20160130715A1

    公开(公告)日:2016-05-12

    申请号:US15001551

    申请日:2016-01-20

    Inventor: Hong XU

    Abstract: A method for manufacturing an aperture plate includes depositing a releasable seed layer above a substrate, applying a first patterned photolithography mask above the releasable seed layer, the first patterned photolithography mask having a negative pattern to a desired aperture pattern, electroplating a first material above the exposed portions of the releasable seed layer and defined by the first mask, applying a second photolithography mask above the first material, the second photolithography mask having a negative pattern to a first cavity, electroplating a second material above the exposed portions of the first material and defined by the second mask, removing both masks, and etching the releasable seed layer to release the first material and the second material. The first and second material form an aperture plate for use in aerosolizing a liquid. Other aperture plates and methods of producing aperture plates are described.

    Abstract translation: 用于制造孔板的方法包括在衬底上沉积可释放种子层,在可释放种子层上方施加第一图案化光刻掩模,将第一图案化光刻掩模具有到所需孔径图案的负图案,将第一材料电镀在第 所述可释放种子层的暴露部分并由所述第一掩模限定,在所述第一材料上方施加第二光刻掩模,所述第二光刻掩模具有负图案到第一空腔,在所述第一材料的暴露部分上方电镀第二材料,以及 由第二掩模限定,去除两个掩模,以及蚀刻可释放种子层以释放第一材料和第二材料。 第一和第二材料形成用于雾化液体的孔板。 描述了其他孔板和制造孔板的方法。

    COUPLING PART WITH INTEGRATED AEROSOL GENERATOR FOR USE IN A BREATHING CIRCUIT

    公开(公告)号:EP4537885A2

    公开(公告)日:2025-04-16

    申请号:EP25161590.2

    申请日:2018-12-06

    Inventor: KERN, Stefan

    Abstract: A coupling part with integrated aerosol generator for use in a breathing circuit, comprising a housing (10) enclosing a cavity (V), having a first opening at a first end prepared for direct or indirect connection to a ventilator, a second opening at a second end, which is suitable for direct or indirect connection to a patient line or an endotracheal tube, wherein an aerosol generator (20) is integrated in one side of the housing and is suitable for delivering an aerosolised liquid, in particular a medicament.

    MOUNTING OF AN AEROSOL GENERATOR APERTURE PLATE TO A SUPPORT

    公开(公告)号:EP4529988A3

    公开(公告)日:2025-04-09

    申请号:EP25157402.6

    申请日:2018-11-27

    Abstract: An aperture plate (1) is attached at its rim (203) to a support washer (3) by adhesive. Anchor grooves (204) having a zig-zag pattern in plan are machined in the lower surface of the rim (203 of the aperture plate before application of the adhesive. The grooves (204) extend out to the edge of the aperture plate (1). The anchor grooves have a depth in the range of 10µm to 40µm, and a width in the range of 20µm to 150µm, and an angular pitch in the range of 2.5° to 12.5°. Excellent bonding strength is achieved for long term reliable attachment in an environment of high frequency vibration and moisture and chemical corrosion.

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