公开(公告)号：KR1020050002704A

公开(公告)日：2005-01-10

申请号：KR1020040095669

申请日：2004-11-22

Applicant: 문창현 ,  대한민국(농촌진흥청장)

Inventor： 안미영 ,  조세연 ,  지상덕 ,  이용기 ,  문창현 ,  정이숙 ,  이보경 ,  김찬식

IPC: A23L1/29

CPC classification number: A23L33/105 ,  A23V2002/00 ,  A23V2200/326 ,  A23V2250/21

Abstract: PURPOSE: A food composition containing Isaria sinclairii(Paecilomyces cicadae) as an effective ingredient is provided. It is useful for preventing or improving disease selected from hypertension, cerebral apoplexy, arteriosclerosis, coronary artery disease, myocardial infarction mediated rise in blood pressure. CONSTITUTION: The food composition for reducing blood pressure contains Isaria sinclairii, a water soluble extract or an alcohol extract. The Isaria sinclairii is selected from infected silkworms, infected pupae, fruit body-forming pupae, artificial or natural cultures. The pharmaceutical composition for reducing blood pressure contains Isaria sinclairii, a water soluble extract or an alcohol extract and a pharmaceutically acceptable carrier. The daily dosage level of the composition is 1 to 10g in single or divided doses.

Abstract translation: 目的：提供含有Isaria sinclairii（Paecilomyces cicadae）作为有效成分的食品组合物。 可用于预防或改善选自高血压，脑中风，动脉硬化，冠状动脉疾病，心肌梗死介导的血压升高的疾病。 构成：用于降低血压的食物组合物含有Isaria sinclairii，水溶性提取物或酒精提取物。 Isaria sinclairii选自感染的蚕，感染蛹，果实体形蛹，人造或天然培养物。 用于降低血压的药物组合物含有Isaria sinclairii，水溶性提取物或醇提取物和药学上可接受的载体。 组合物的日剂量水平为单剂量或分剂量为1至10g。

公开(公告)号：KR100462166B1

公开(公告)日：2004-12-16

申请号：KR1020010013729

申请日：2001-03-16

Applicant: 대한민국(농촌진흥청장) ,  최진호

Inventor： 류강선 ,  안미영 ,  이희삼 ,  김진원 ,  김익수 ,  이용기 ,  김은선 ,  강필돈 ,  김미자 ,  최진호 ,  김동우 ,  김대익 ,  박수현 ,  김정민

IPC: A61K35/64 ,  A23L1/30

Abstract: PURPOSE: Provided is an extract derived from male pupae and adults of silkworm. Also, its preparation method and foods and pharmaceutical compositions containing it. The extract contains active ingredient for treating impotency, and is thus used as a material for manufacturing medicines. CONSTITUTION: The method for manufacturing the extract of male pupae and adults of silkworm is characterized by selecting male pupae and adults of silkworm using a silkworm kind of which gender can be distinguishable by colors, patterns or the like. The pharmaceutical composition characteristically contains an effective amount of the extract.

Abstract translation: 用途：提供来自雄蚕蛹和成虫的提取物。 其制备方法以及含有它的食品和药物组合物。 提取物含有用于治疗无力的活性成分，因此用作制造药物的材料。 组成：用于制造雄蚕蛹和蚕成虫的提取物的方法的特征在于，选择使用可通过颜色，图案等区分性别的蚕种的雄蚕和成虫。 该药物组合物的特征在于含有有效量的提取物。

公开(公告)号：KR200360922Y1

公开(公告)日：2004-09-06

申请号：KR2020040010145

申请日：2004-04-13

Applicant: 대한민국(농촌진흥청장)

Inventor： 류강선 ,  안미영 ,  김진원 ,  김익수 ,  이용기 ,  이희삼 ,  김은선 ,  박광영 ,  이평재

IPC: A01K67/04

CPC classification number: A01K67/04

Abstract: 본 고안은 누에 수거 작업의 손쉬운 처리를 위하여 개발된 생력형 누에 수거기에 관한 것으로, 본 고안에 의한 누에 수거기는 진공청소기의 원리를 이용하여 손잡이가 부착된 진공 호스를 착탈식 누에 수거함 및 모터가 장착된 누에 수거기 본체에 연결한 것이다. 본 고안에 의한 누에 수거기는 누에 수거시 누에의 파손을 막기 위하여 진공 호스부분의 굴곡부분을 보완하였으며, 바퀴를 달아 이동을 용이하게 하였다. 본 고안에 의한 누에 수거기는 기존의 방법으로 누에를 수거할 때와 동일한 품질을 유지하면서도 기존의 방법에 비해 처리시간을 단축시키고 노동력을 절감시켜 수거의 효율을 높일 수 있다.

公开(公告)号：KR1020040018233A

公开(公告)日：2004-03-02

申请号：KR1020030094612

申请日：2003-12-22

Applicant: 대한민국(농촌진흥청장)

Inventor： 안미영 ,  류강선 ,  이용우 ,  김영식 ,  이용기 ,  이희삼 ,  김은선 ,  김익수

IPC: A61K35/64

CPC classification number: A61K35/63

Abstract: PURPOSE: Provided is a pharmaceutical composition containing a cricket extract is provided which has liver-protective effect, antifatigue effect, alcohol detoxification effect, and lipid-peroxidation formation inhibition effect. CONSTITUTION: A pharmaceutical composition for liver-protection, alcohol detoxification, and lipid-peroxidation formation inhibition is characterized by containing, as an active ingredient, a cricket extract which is prepared by using C1-C4 alcohol as an extraction solvent. It is formulated into a drink.

Abstract translation: 目的：提供含有蟋蟀提取物的药物组合物，其具有肝保护作用，抗疲劳作用，醇解毒作用和脂质过氧化形成抑制作用。 构成：用于肝保护，酒精解毒和脂质 - 过氧化物形成抑制的药物组合物的特征在于，含有通过使用C1-C4醇作为提取溶剂制备的板球提取物作为活性成分。 它被制成一杯饮料。

公开(公告)号：KR1020030078549A

公开(公告)日：2003-10-08

申请号：KR1020020017665

申请日：2002-03-30

Applicant: 문창현 ,  대한민국(농촌진흥청장)

Inventor： 안미영 ,  조세연 ,  지상덕 ,  이용기 ,  문창현 ,  정이숙 ,  이보경 ,  김찬식

IPC: A61K36/066 ,  A61P9/12

Abstract: PURPOSE: Provided is a composition comprising Isaria sinclairii itself, and its water soluble extract or alcohol extract as an active ingredient, thereby reducing blood pressure and body weight. CONSTITUTION: A composition for decreasing blood pressure is characterized by containing Isaria sinclairii itself, and its water soluble extract or alcohol extract as an active ingredient. It is also capable of being applied to health foods.

Abstract translation: 目的：提供包含Isaria sinclairii本身及其水溶性提取物或醇提取物作为活性成分的组合物，从而降低血压和体重。 构成：用于降低血压的组合物的特征在于含有Isaria sinclairii本身，其水溶性提取物或醇提取物作为活性成分。 它也可以应用于保健食品。

公开(公告)号：KR100396986B1

公开(公告)日：2003-09-17

申请号：KR1020010011449

申请日：2001-03-06

Applicant: 대한민국(농촌진흥청장) ,  사회복지법인 삼성생명공익재단

Inventor： 이희삼 ,  류강선 ,  김진원 ,  김익수 ,  이용기 ,  안미영 ,  김은선 ,  김광원 ,  서수원

IPC: C07D211/14

Abstract: PURPOSE: Provided is a process for preparing α-glycosidase inhibitor derived from powdery silkworm, which has the same decreasing effect of blood glucose level as acarbose which is a conventional therapeutic agent for diabetes. CONSTITUTION: The process for preparing α-glycosidase inhibitor comprises the steps of: freeze-drying and powdering silkworm then adding 50% ethanol to extract it; performing cation exchange column chromatography with the extract then followed by eluting it with 0.5N of NH4OH and concentrating it; dissolving the concentrate in water then followed by performing anion exchange column chromatography. eluting with water and concentrating it; dissolving the concentrate in water then followed by cation exchange column chromatography, eluting with water and 0.5N of NH4OH to obtain 5 fractions obtain one fraction respectively; and performing anion exchange column chromatography with the second fraction among the 6 fractions to obtain pure 1-dioxynojirimycin fraction.

Abstract translation: 目的：提供一种制备来源于粉状蚕的α-糖苷酶抑制剂的方法，其具有与作为常规糖尿病治疗剂的阿卡波糖相同的血糖水平降低效果。 构成：制备α-糖苷酶抑制剂的方法包括以下步骤：将家蚕冷冻干燥并粉碎，然后加入50％乙醇以提取它; 用提取物进行阳离子交换柱层析，然后用0.5N NH 4 OH洗脱并浓缩; 将浓缩物溶于水中，然后进行阴离子交换柱层析。 用水洗脱并浓缩; 将浓缩物溶于水中，然后进行阳离子交换柱层析，用水和0.5N NH 4 OH洗脱以获得5个馏分，分别得到一个馏分; 用6个级分中的第二级分进行阴离子交换柱层析，得到纯的1-二氧代野my霉素级分。

公开(公告)号：KR1020020025637A

公开(公告)日：2002-04-04

申请号：KR1020010013729

申请日：2001-03-16

Applicant: 대한민국(농촌진흥청장) ,  최진호

Inventor： 류강선 ,  안미영 ,  이희삼 ,  김진원 ,  김익수 ,  이용기 ,  김은선 ,  강필돈 ,  김미자 ,  최진호 ,  김동우 ,  김대익 ,  박수현 ,  김정민

IPC: A61K35/64 ,  A23L1/30

CPC classification number: A23L33/10 ,  A61K35/63

Abstract: PURPOSE: Provided is an extract derived from male pupae and adults of silkworm. Also, its preparation method and foods and pharmaceutical compositions containing it. The extract contains active ingredient for treating impotency, and is thus used as a material for manufacturing medicines. CONSTITUTION: The method for manufacturing the extract of male pupae and adults of silkworm is characterized by selecting male pupae and adults of silkworm using a silkworm kind of which gender can be distinguishable by colors, patterns or the like. The pharmaceutical composition characteristically contains an effective amount of the extract.

Abstract translation: 目的：提供来源于雄蛹和蚕成虫的提取物。 此外，其制备方法和含有它的食品和药物组合物。 提取物含有用于治疗阳ency的活性成分，因此用作制造药物的材料。 构成：制作蚕蛹和成蚕提取物的方法的特征在于使用蚕种选择蛹虫蛹和成虫，性别可以通过颜色，图案等进行区分。 药物组合物特征性地含有有效量的提取物。