公开(公告)号：EP3160533A4

公开(公告)日：2018-03-28

申请号：EP15812715

申请日：2015-03-04

Applicant: MEDTRONIC INC

Inventor： GERBER MARTIN T ,  HOBOT CHRISTOPHER M

IPC: A61M1/14 ,  A61M1/16 ,  B01D15/20

CPC classification number: A61M1/1696

Abstract: A sorbent pouch for use in sorbent dialysis. The sorbent pouch allows for fluid to freely pass into and through the sorbent materials, while keeping the sorbent materials inside the sorbent pouch.

公开(公告)号：EP3160531A4

公开(公告)日：2018-03-21

申请号：EP15811439

申请日：2015-02-27

Applicant: MEDTRONIC INC

Inventor： GERBER MARTIN T ,  HOBOT CHRISTOPHER M

IPC: A61M1/14 ,  A61M1/16

CPC classification number: A61M1/1696

Abstract: An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis. The sorbent cartridge is configured to allow an amount of urease to be added to the sorbent cartridge. A urease solution can be injected into the sorbent cartridge to replenish the urease containing module, or solid urease can be added to the sorbent cartridge. The sorbent module can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.

公开(公告)号：EP3160610A4

公开(公告)日：2018-03-14

申请号：EP15812413

申请日：2015-05-26

Applicant: MEDTRONIC INC

Inventor： PUDIL BRYANT J ,  GERBER MARTIN T ,  HOBOT CHRISTOPHER M

IPC: A61M1/14 ,  A61M1/16

CPC classification number: A61M1/1696 ,  B01J39/09 ,  C01B25/45

Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include passing solutions containing combinations of acids, bases and salts through a module containing a rechargeable sorbent material such as zirconium phosphate in order to replace ions bound to the zirconium phosphate with hydrogen and sodium ions. The method allows for a customizable zirconium phosphate, with control over the ratios of sodium to hydrogen on the recharged zirconium phosphate.

公开(公告)号：EP3160530A4

公开(公告)日：2018-03-14

申请号：EP15811326

申请日：2015-03-11

Applicant: MEDTRONIC INC

Inventor： PUDIL BRYANT J ,  LYU SUPING ,  GROVENDER ERIC ,  HOBOT CHRISTOPHER M ,  GERBER MARTIN T

IPC: A61M1/14 ,  A61M1/16

CPC classification number: A61M1/1696 ,  B01J39/09 ,  C01B25/45

Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include passing solutions containing combinations of acids, bases and salts through a module containing a rechargeable sorbent material such as zirconium phosphate in order to replace ions bound to the zirconium phosphate with hydrogen and sodium ions. The method allows for a customizable zirconium phosphate, with control over the ratios of sodium to hydrogen on the recharged zirconium phosphate.

公开(公告)号：EP3160536A4

公开(公告)日：2018-03-07

申请号：EP15812559

申请日：2015-03-11

Applicant: MEDTRONIC INC

Inventor： GERBER MARTIN T ,  HOBOT CHRISTOPHER M

IPC: A61M1/16 ,  A61M1/34

CPC classification number: A61M1/1696 ,  A61M2205/18 ,  A61M2205/33 ,  B01D61/30 ,  B01D61/32 ,  B01J20/0211 ,  B01J20/34

Abstract: A reserve zirconium phosphate module for continuing dialysis in the event the capacity of the original zirconium phosphate module is exceeded. The sorbent cartridge can have a sensor for detecting when the capacity of the zirconium phosphate material has been exceeded, and a valve assembly for diverting the flow of spent dialysate into the reserve module when needed. Any of the modules of the sorbent cartridge can be reusable and the sorbent materials therein recharged.

公开(公告)号：EP2285363A4

公开(公告)日：2012-03-07

申请号：EP09731770

申请日：2009-04-17

Applicant: WARSAW ORTHOPEDIC INC ,  MEDTRONIC INC

Inventor： ZANELLA JOHN MYERS ,  KING VANJA MARGARETA ,  HOBOT CHRISTOPHER M ,  MCKAY WILLIAM F ,  HILDEBRAND KEITH R

IPC: A61K31/415 ,  A61K9/00 ,  A61K9/20 ,  A61K31/137 ,  A61K31/56 ,  A61K31/573 ,  A61P29/00

CPC classification number: A61K31/137 ,  A61K9/0024 ,  A61K9/14 ,  A61K31/415 ,  A61K31/4162

公开(公告)号：EP2288353A4

公开(公告)日：2011-03-02

申请号：EP09732436

申请日：2009-04-17

Applicant: WARSAW ORTHOPEDIC INC ,  MEDTRONIC INC

Inventor： ZANELLA JOHN MYERS ,  KING VANJA MARGARETA ,  HOBOT CHRISTOPHER M ,  HILDEBRAND KEITH R

IPC: A61K31/415 ,  A61K9/20 ,  A61K31/56 ,  A61K31/573 ,  A61P29/00

CPC classification number: A61K31/415 ,  A61K9/0024 ,  A61K9/0085 ,  A61K9/06 ,  A61K9/5031 ,  A61K9/5073 ,  A61K31/56 ,  A61K47/10 ,  A61K47/32 ,  A61K47/38

公开(公告)号：EP3160529A4

公开(公告)日：2018-03-21

申请号：EP15810804

申请日：2015-03-11

Applicant: MEDTRONIC INC

Inventor： GERBER MARTIN T ,  HOBOT CHRISTOPHER M

IPC: A61M1/14 ,  A61M1/16 ,  B01D15/20

CPC classification number: B01D15/203 ,  A61M1/1696 ,  A61M2202/0057 ,  A61M2205/18 ,  A61M2205/33

Abstract: An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis using urease pouches. The sorbent cartridge is configured to allow insertion of a urease pouch or injection of a urease solution into the sorbent cartridge containing a urease pouch. The sorbent module can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.

公开(公告)号：EP3160535A4

公开(公告)日：2018-03-07

申请号：EP15812252

申请日：2015-03-11

Applicant: MEDTRONIC INC

Inventor： GERBER MARTIN T ,  HOBOT CHRISTOPHER M

IPC: A61M1/16 ,  A61M1/34

CPC classification number: A61M1/1696 ,  A61M1/1611 ,  A61M1/1613 ,  A61M2205/121 ,  A61M2205/33 ,  B01D15/08

Abstract: A customizable modular dialysate regeneration assembly with connectable sorbent packaging systems. The dialysate regeneration assembly can be customized based on patient parameters or dialysis session parameters. A processor can be included that can determine the correct amount of each sorbent material necessary for a given patient and a given dialysis session.

公开(公告)号：EP3160534A4

公开(公告)日：2018-03-07

申请号：EP15811454

申请日：2015-03-11

Applicant: MEDTRONIC INC

Inventor： GERBER MARTIN T ,  HOBOT CHRISTOPHER M

IPC: B01J20/28 ,  A61M1/16 ,  A61M1/34 ,  B01J20/02 ,  B01J20/06 ,  B01J20/20 ,  B01J20/22

CPC classification number: B01J20/28052 ,  A61M1/1696 ,  B01J20/0211 ,  B01J20/06 ,  B01J20/20 ,  B01J20/22 ,  B01J2220/66

Abstract: A stacked sorbent assembly for use in sorbent dialysis. The stacked sorbent assembly contains two or more interchangeable sorbent pouches that allow for fluid to freely pass into and through the sorbent materials, while keeping the sorbent materials inside the sorbent pouches. Any of the pouches in the sorbent cartridge can be reused and/or recharged.