Porous PEEK article as an implant
    135.
    发明公开
    Porous PEEK article as an implant 有权
    PoröserPEEK-Gegenstand als ein Implantat

    公开(公告)号:EP2338532A3

    公开(公告)日:2013-03-20

    申请号:EP10382243.3

    申请日:2010-09-10

    Abstract: The present invention refers to a porous PEEK-type polymer article comprising a porous PEEK-type polymer structure and presenting at least a trimodal pore distribution. The invention describes a process for the production of said porous PEEK-type polymer article comprising: a) contacting a PEEK-type polymer with a composition comprising at least a organic solvent, b) heating at a temperature at which the PEEK-type polymer is dissolved, c) adding at least a porogen agent, d) cooling the mixture obtained in c) at a temperature at least equal or lower than the temperature at which the PEEK-type polymer precipitates, e) forming said cooled mixture into a shaped article, f) removing the organic solvent and the porogen agent, and g) recovering the PEEK-type polymer article.

    Abstract translation: 本发明涉及一种多孔PEEK型聚合物制品,其包含多孔PEEK型聚合物结构并呈现至少三峰孔分布。 本发明描述了一种生产所述多孔PEEK型聚合物制品的方法,包括:a)使PEEK型聚合物与至少包含有机溶剂的组合物接触,b)在PEEK型聚合物为 溶解,c)至少加入致孔剂,d)在至少等于或低于PEEK型聚合物沉淀的温度的温度下冷却在c)中获得的混合物,e)将所述冷却的混合物形成成型制品 ,f)除去有机溶剂和致孔剂,g)回收PEEK型聚合物制品。

    Biocompatible polymers and methods of use
    137.
    发明公开
    Biocompatible polymers and methods of use 审中-公开
    生物相容性聚合物和使用方法

    公开(公告)号:EP2093256A2

    公开(公告)日:2009-08-26

    申请号:EP09004700.2

    申请日:2006-07-28

    Abstract: Compositions and methods for manufacturing polymers are disclosed. Compositions include novel plastics, including films and shaped forms comprising polymer matrices that are biologically compatible and biodegradable. Such plastics may comprise polymers derived from natural sources. Further, such plastics are useful in biological systems for wound repair, implants, stents, drug encapsulation and delivery, and other applications. The disclosed methods comprise mild manufacturing processes such that various additives, such as biologically active proteins, sugars, lipids, and the like may be incorporated into the polymer matrix without subsequent loss of bioactivity during processing. Additionally, methods of manufacture for controlling mechanical properties, such as elasticity, pliancy, and the porosity of such plastics are disclosed.

    Abstract translation: 公开了用于制造聚合物的组合物和方法。 组合物包括新型塑料,包括薄膜和包含聚合物基质的成型形式,所述聚合物基质是生物相容的并且可生物降解的。 这种塑料可以包含衍生自天然来源的聚合物。 此外,此类塑料可用于伤口修复的生物系统,植入物,支架,药物包封和递送以及其他应用。 所公开的方法包括温和的制造过程,使得可以将各种添加剂(例如生物活性蛋白质,糖,脂质等)并入聚合物基质中,而不会随后在加工过程中丧失生物活性。 另外,公开了用于控制机械性能如弹性,柔韧性和这种塑料的孔隙率的制造方法。

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