公开(公告)号：EP2593787A2

公开(公告)日：2013-05-22

申请号：EP11736199.8

申请日：2011-07-15

Applicant: Stichting VU-VUmc

Inventor： WÜRDINGER, Thomas ,  NILSSON, Rolf Jonas

IPC: G01N33/48

CPC classification number: C12Q1/6827 ,  C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/158

Abstract: The present invention relates to a method of analyzing a blood sample of a subject for the presence of a disease marker, said method comprising the steps of a) extracting nucleic acid from anucleated blood cells in said blood sample to provide an anucleated blood cells-extracted nucleic acid fraction, and b) analysing said anucleated blood cells-extracted nucleic acid fraction for the presence of a disease marker, wherein said disease marker is a disease-specific mutation in a gene of a cell of said subject, or wherein said disease marker is a disease-specific expression profile of genes of a cell of said subject.