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    APPARATUS AND METHODS FOR MRI-COMPATIBLE HAPTIC INTERFACE
    152.
    发明申请
    APPARATUS AND METHODS FOR MRI-COMPATIBLE HAPTIC INTERFACE 审中-公开
    用于MRI兼容性界面的装置和方法

    公开(公告)号：WO2011057260A2

    公开(公告)日：2011-05-12

    申请号：PCT/US2010/056020

    申请日：2010-11-09

    Applicant: WORCESTER POLYTECHNIC INSTITUTE ,  FISCHER, Gregory, S. ,  SU, Hao

    Inventor： FISCHER, Gregory, S. ,  SU, Hao

    IPC: A61B5/055

    CPC classification number: A61B10/0241 ,  A61B34/30 ,  A61B34/37 ,  A61B34/76 ,  A61B90/11 ,  A61B2090/064 ,  A61B2090/374

    Abstract: In one embodiment, the system of these teachings includes a master robot/haptic device providing haptic feedback to and receiving position commands from an operator, a robot controller receiving position information and providing force information to the master robot/haptic device, a navigation component receiving images from an MRI scanner, the navigation component providing trajectory planning information to the robot controller, a slave robot driving a needle, the slave robot receiving control information from the robot controller, and a fiberoptic sensor operatively connected to the slave robot; the fiberoptic sensor providing data to the robot controller; the data being utilized by the robot controller to provide force information to the master robot/haptic device. In one instance, the present teachings include a fiberoptic force sensor and an apparatus for integrating the fiberoptic sensor into a teleoperated MRI-compatible surgical system. Methods for use are also disclosed.

    Abstract translation: 在一个实施例中，这些教导的系统包括主机器人/触觉装置，其向操作者提供触觉反馈并且接收来自操作者的位置命令，机器人控制器接收位置信息并向主机器人/触觉装置提供力信息，导航部件接收 来自MRI扫描仪的图像，导航部件向机器人控制器提供轨迹规划信息，从机器人驱动针，从机器人接收来自机器人控制器的控制信息，以及可操作地连接到从机器人的光纤传感器; 光纤传感器向机器人控制器提供数据; 由机器人控制器利用的数据向主机器人/触觉装置提供力信息。 在一个实例中，本教导包括光纤力传感器和用于将光纤传感器集成到远程操作的MRI兼容手术系统中的装置。 还公开了使用方法。

    WIRELESS ULTRASOUND TRANSDUCER USING ULTRAWIDEBAND
    154.
    发明申请
    WIRELESS ULTRASOUND TRANSDUCER USING ULTRAWIDEBAND 审中-公开
    使用超宽带的无线超声换能器

    公开(公告)号：WO2008115312A2

    公开(公告)日：2008-09-25

    申请号：PCT/US2008/001068

    申请日：2008-01-28

    Applicant: WORCESTER POLYTECHNIC INSTITUTE ,  PEDERSEN, Peder, C. ,  SZABO, Thomas, L. ,  CORDEIRO, Philip, Joseph

    Inventor： PEDERSEN, Peder, C. ,  SZABO, Thomas, L. ,  CORDEIRO, Philip, Joseph

    IPC: H04B11/00

    CPC classification number: A61B8/00 ,  A61B8/4218 ,  A61B8/4472 ,  A61B8/461 ,  A61B8/56 ,  A61B8/565 ,  A61B8/585 ,  G01S7/003 ,  G01S7/52079 ,  G01S7/5208 ,  G01S15/899 ,  G06F19/00 ,  G06F19/3418

    Abstract: Ultrasound imaging systems and methods are described that include a cableless front end having a UltraWideBand transceiver and a beamformer that transmit ultrasound data to a back end physically separated from the front end, with the back end having a UltraWideBand transceiver for receiving ultrasound data from the front end UltraWideBand transceiver via a peer-to-peer communication protocol. The back end unit can also receive and transmit commands to and from the front end unit to select an image mode and has a signal processor and scan converter that can convert ultrasound data into image data for display. An input device in the front end allows the operator to selectively display ultrasound data or patient data on an auxiliary worn display or the nearest local display.

    Abstract translation: 描述了超声成像系统和方法，其包括具有UltraWideBand收发器和波束形成器的无线前端，波束形成器将超声波数据发送到与前端物理分离的后端，后端具有超宽带 收发器，用于经由对等通信协议从前端UltraWideBand收发器接收超声数据。 后端单元还可以接收和发送去往和来自前端单元的命令以选择图像模式，并且具有信号处理器和扫描转换器，其可以将超声数据转换成图像数据以供显示。 前端的输入设备可让操作员在辅助佩戴的显示器或最近的本地显示器上选择性显示超声数据或患者数据。

    TARGETS, INCLUDING YAP1, FOR ANTIFUNGAL DRUG DISCOVERY AND THERAPY
    156.
    发明申请
    TARGETS, INCLUDING YAP1, FOR ANTIFUNGAL DRUG DISCOVERY AND THERAPY 审中-公开
    目标，包括YAP1，用于抗真菌药物发现和治疗

    公开(公告)号：WO2008073900A1

    公开(公告)日：2008-06-19

    申请号：PCT/US2007/086998

    申请日：2007-12-10

    Applicant: WORCESTER POLYTECHNIC INSTITUTE (WPI) ,  RAO, Reeta, Prusty ,  POLITZ, Samuel, Michael

    Inventor： RAO, Reeta, Prusty ,  POLITZ, Samuel, Michael

    IPC: C12N1/20

    CPC classification number: C12N1/18 ,  A01K67/0336 ,  A01K2227/703 ,  A01K2267/03 ,  C12Q1/18 ,  G01N2333/395 ,  G01N2333/43534

    Abstract: The present invention is based on the discovery of a two organism model system that can be used to identify virulence factors. The system is also useful in the process of drug delivery. More specifically, we have established valid fungal infection in caenorhabditis elegans with an invading pathogen, the yeast Saccharomyces cerevisiae . Because both species are genetic model organisms, the assay can be used to identify host and virulence factors involved in such interactions.

    Abstract translation: 本发明基于可用于鉴定毒力因子的两种生物体模型系统的发现。 该系统在药物递送过程中也是有用的。 更具体地说，我们已经在具有入侵病原体，酵母酿酒酵母的秀丽隐杆线虫中建立了有效的真菌感染。 因为这两种物种都是遗传模式生物，所以该测定可用于鉴定参与这种相互作用的宿主和毒力因子。

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