DRUG DELIVERY SYSTEM AND METHOD OF MANUFACTURING THEREOF

    公开(公告)号:WO2007092894A3

    公开(公告)日:2007-08-16

    申请号:PCT/US2007/061787

    申请日:2007-02-07

    Abstract: Medical devices implanted or otherwise used in a mammal are made less prone to trigger adverse reactions by use of gas cluster ion-beam (GCIB) surface modification adhere various drug molecules directly into or onto the surface of medical devices, and optionally building adhered drug layers upon the first adhered layer to obtain a desired drug elution profile. This is accomplished without the need for a polymer or any other binding agent to retain the drug.

    FIRE SUPPRESSION USING WATER MIST WITH ULTRAFINE SIZE DROPLETS
    154.
    发明申请
    FIRE SUPPRESSION USING WATER MIST WITH ULTRAFINE SIZE DROPLETS 审中-公开
    使用具有超大尺寸喷雾器的水雾的消防措施

    公开(公告)号:WO2003024618A1

    公开(公告)日:2003-03-27

    申请号:PCT/US2002/029789

    申请日:2002-09-19

    Abstract: An improved method and apparatus for producing an extremely fine micron and sub-micron size water mist (18) using an electronic ultrasonic device (8) that produces the mist at ambient-pressure and delivering the mist for application in suppressing fire. A piezoelectric transducer (10) is arranged to produce a water mist having at least a portion of sub-micron size droplets. The water mist is produced by high frequency pressure waves or ultrasonic waves of predetermined or variable frequency, including frequencies which may exceed 2.5 MHz. The water mist is directed to a firebase to be self-entrained by the fire's flame. The momentum provided the water mist in directing the mist is minimized to enhance the ability of the fire to entrain the mist, and the flow of the carrier medium is usually directed tangentially about the water fountain (16) creating the mist. Further, the throughput and concentration of the mist is controlled to ensure that the entrained mist will be sufficient to cool and suppress the fire. The water mist may be effectively utilized for mitigating blast and reducing over pressures. The fine water mist may also be utilized for humidification because of its fast vaporization and efficient cooling behavior. The apparatus may be modified in its physical design and direction of output, and the method may be modified by adjusting the throughput of mist, composition of mist, concentration of mist, and momentum of mist, whereby fire may be suppressed under many different scenarios.

    Abstract translation: 一种改进的使用电子超声装置(8)制造极细微米和亚微米尺寸的水雾(18)的方法和装置,其在环境压力下产生雾气并传送雾以用于抑制火灾。 压电换能器(10)被布置成产生具有亚微米级液滴的至少一部分的水雾。 水雾由高频压力波或预定或可变频率的超声波产生,包括可能超过2.5MHz的频率。 水雾被引导到火基地,被火焰的火焰自动夹带。 动量提供了将雾中引导的水雾最小化以增强火焰夹带雾的能力,并且载体介质的流动通常围绕产生雾的喷泉(16)切向地引导。 此外,控制雾的产量和浓度,以确保夹带的雾足以冷却和抑制火。 水雾可以有效地用于减轻爆炸和减少过压。 由于其快速蒸发和有效的冷却行为,细水雾也可用于加湿。 该装置可以在其物理设计和输出方向上进行修改,并且可以通过调节雾的生成量,雾的组成,雾的浓度和雾的动量来修改该方法,从而可以在许多不同的情况下抑制火灾。

    APPARATUS AND METHOD FOR COATING THE OUTER SURFACE OF A WORKPIECE
    156.
    发明申请
    APPARATUS AND METHOD FOR COATING THE OUTER SURFACE OF A WORKPIECE 审中-公开
    涂装工件外表面的装置和方法

    公开(公告)号:WO01072434A1

    公开(公告)日:2001-10-04

    申请号:PCT/US2001/008845

    申请日:2001-03-20

    CPC classification number: B05B13/0421 B05B7/2405 C23C4/129

    Abstract: A method and apparatus for coating the outer surface of a workpiece (W) comprises disposing a workpiece (W) in a fixed position along an axis and rotating a thermal spray gun (7) around the axis on a support (5) with a thermal spray (S) thereof directed towards the axis. The powder, fuel and oxygen are rotatably coupled to the gun (7) and the thermal spray gun (7) and the support (5) are moved along the axis while rotating.

    Abstract translation: 一种用于涂覆工件(W)的外表面的方法和设备包括将工件(W)沿着轴线设置在固定位置,并将热喷枪(7)围绕轴线旋转在具有热量的支撑件(5)上 喷雾(S)指向轴线。 粉末,燃料和氧气可旋转地联接到枪(7),并且热喷枪(7)和支撑件(5)在旋转的同时沿着轴线移动。

    METHOD AND DEVICE FOR PLASMA COATING SURFACES
    157.
    发明申请
    METHOD AND DEVICE FOR PLASMA COATING SURFACES 审中-公开
    方法和设备等离子表面涂覆

    公开(公告)号:WO01032949A1

    公开(公告)日:2001-05-10

    申请号:PCT/EP2000/002401

    申请日:2000-03-17

    CPC classification number: H05H1/42 C23C4/134 C23C8/36 H05H1/34

    Abstract: The invention relates to a method for coating surfaces, according to which a precursor material is made to react by way of a plasma and the reaction product is deposited on the surface (34), both the reaction and the deposition proceeding at atmospheric pressure. According to the inventive method, a plasma jet (28) is produced by passing a working gas through an excitation zone (12) and the precursor material is supplied to the plasma jet by means of a lancet (32) separately from the working gas.

    Abstract translation: 一种用于涂覆表面的方法,其中使通过等离子体的装置,前体反应,将反应产物的表面上(34)被沉积,进行两个反应,以及在大气压下的沉积,通过使工作气体通过,其特征在于 一个激发区(12)中产生等离子流(28)和所述前体材料与矛杆(32)从所述工作气体分别送入等离子流。

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