公开(公告)号：WO2012070760A1

公开(公告)日：2012-05-31

申请号：PCT/KR2011/007096

申请日：2011-09-27

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  CHO, So Hye ,  PARK, Jong Ku ,  JIE, Hyun Seock ,  CHOI, Hyoung Il ,  SONG, Bong Geun

Inventor： CHO, So Hye ,  PARK, Jong Ku ,  JIE, Hyun Seock ,  CHOI, Hyoung Il ,  SONG, Bong Geun

IPC: C01G23/047 ,  H01L31/042 ,  H01B1/08 ,  B82B3/00

CPC classification number: H01G9/2031 ,  B82Y30/00 ,  C01G23/047 ,  C01G23/07 ,  C01P2002/78 ,  C01P2002/82 ,  C01P2002/84 ,  C01P2004/42 ,  C01P2004/64 ,  C01P2006/12 ,  C01P2006/14 ,  H01G9/0029 ,  Y02E10/542

Abstract: It is disclosed that titania nanoparticles adequate for fabricating a photo-electrode of a dye-sensitized solar cell which is efficient and longlasting and a fabrication method thereof. The titania nanoparticles can provide high photoelectric conversion efficiency of the solar cell with help of fast electron mobility due to its high crystallinity and can reduce process time required for adsorbing the dye molecules on the surface of the titania nanoparticles. By modifying surface characteristics of the titania nanoparticles, it is allowed for dye molecules to be easily adsorbed on the surface of the titania nanoparticles and the life span of the dye molecules adsorbed on it is expanded with help of reduced photo-degradation rate of them at service conditions.

Abstract translation: 公开了适于制造染料敏化太阳能电池的光电极的二氧化钛纳米颗粒，其是高效和长寿命的及其制造方法。 由于其高结晶度，二氧化钛纳米颗粒可以帮助快速的电子迁移率提供太阳能电池的高光电转换效率，并且可以减少吸附二氧化钛纳米颗粒表面上的染料分子所需的工艺时间。 通过改变二氧化钛纳米颗粒的表面特性，允许染料分子容易地吸附在二氧化钛纳米颗粒的表面上，并且吸附在其上的染料分子的寿命被扩大，借助于其降低的光降解速率 服务条件。

公开(公告)号：WO2011136452A1

公开(公告)日：2011-11-03

申请号：PCT/KR2010/007869

申请日：2010-11-09

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  PARK, Jong Ku ,  CHO, So Hye ,  CHOI, Pyuck Pa ,  PARK, Su Young

Inventor： PARK, Jong Ku ,  CHO, So Hye ,  CHOI, Pyuck Pa ,  PARK, Su Young

IPC: C01B33/18 ,  C01B37/02 ,  C09D1/00 ,  G02B1/02

CPC classification number: C01B33/18 ,  C01P2002/72 ,  C01P2002/82 ,  C01P2004/03 ,  C01P2004/04 ,  C08K3/22 ,  C08K3/36 ,  C08K7/26 ,  C09D1/02 ,  C09D7/70

Abstract: The present invention relates to a method of treating spherical oxide particles comprising subjecting the spherical oxide particles to heat treatment above room temperature. Spherical oxide particles synthesized by a sol-gel method, specifically silica particles, are heat treated to minimize defects occurring during particle alignment, thereby eventually enhancing the volume stability of the silica particles. Since a silica layer with less structural defects fabricated according to the present invention has high physical stability and provides high crystallinity over a large area, it can be used in fields that require photonic crystals having superior optical properties, such as light refractive layers, waveguides, etc.

Abstract translation: 本发明涉及一种处理球形氧化物颗粒的方法，包括使球形氧化物颗粒在室温以上进行热处理。 通过溶胶 - 凝胶法合成的球形氧化物颗粒，特别是二氧化硅颗粒，进行热处理，以最大限度地减少颗粒排列期间发生的缺陷，从而最终提高二氧化硅颗粒的体积稳定性。 由于根据本发明制造的具有较少结构缺陷的二氧化硅层具有高的物理稳定性并且在大面积上提供高结晶度，因此可用于需要具有优异光学性质的光子晶体的领域，例如光折射层，波导管， 等等

公开(公告)号：WO2011081277A2

公开(公告)日：2011-07-07

申请号：PCT/KR2010/005700

申请日：2010-08-25

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  YOO, Bok Ryul ,  HAN, Joon Soo ,  YOO, Jang Hyun

Inventor： YOO, Bok Ryul ,  HAN, Joon Soo ,  YOO, Jang Hyun

IPC: C07F15/00

CPC classification number: C07F15/00 ,  C07D233/02 ,  C07D239/04 ,  C07F7/14 ,  C07F15/0006 ,  C07F15/0086 ,  C07F15/04 ,  C08G77/08

Abstract: Provided are a saturated N-heterocyclic carbene-ligand metal complex derivative, a method for preparing the same, and a method for preparing a silane compound by hydrosilylation using the same as a catalyst. To describe in more detail, the metal complex derivative has a saturated N-heterocyclic carbene derivative and an olefin ligand at the same time. A silane compound is prepared by hydrosilylation in the presence of the metal complex derivative as a catalyst. The provided metal complex derivative of the present invention has superior stability during hydrosilylation reaction and is capable of effectively performing the hydrosilylation reaction at low temperature even with small quantity. Further, a product with superior regioselectivity may be obtained. In addition, after the hydrosilylation reaction is completed, the metal complex derivative may be recovered and recycled.

Abstract translation: 本发明提供饱和的N-杂环卡宾 - 配体金属配合物衍生物，其制备方法，以及使用其作为催化剂通过氢化硅烷化制备硅烷化合物的方法。 为了更详细地描述，金属配合物衍生物同时具有饱和的N-杂环卡宾衍生物和烯烃配体。 在作为催化剂的金属络合物衍生物存在下通过氢化硅烷化来制备硅烷化合物。 所提供的本发明的金属络合物衍生物在氢化硅烷化反应中具有优异的稳定性，并且即使在少量的情况下也能够在低温下有效地进行氢化硅烷化反应。 此外，可以获得具有优异的区域选择性的产物。 另外，在氢化硅烷化反应完成之后，金属络合物衍生物可被回收和再循环。

公开(公告)号：WO2011049274A1

公开(公告)日：2011-04-28

申请号：PCT/KR2010/000589

申请日：2010-02-01

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  HAH, Jung-Mi ,  YOO, Kyung Ho ,  SIM, Tae-Bo ,  OH, Chang Hyun ,  LEE, Jung Hun ,  YU, Hana ,  KIM, Hwan

Inventor： HAH, Jung-Mi ,  YOO, Kyung Ho ,  SIM, Tae-Bo ,  OH, Chang Hyun ,  LEE, Jung Hun ,  YU, Hana ,  KIM, Hwan

IPC: C07D401/04 ,  C07D401/02 ,  A61K31/415 ,  A61P35/00

CPC classification number: C07D403/14 ,  A61K31/415 ,  C07D403/04 ,  C07D405/14 ,  C07D413/14 ,  C07D417/14

Abstract: The present invention relates to novel imidazole derivatives or pharmaceutically acceptable salts thereof, preparation methods thereof and pharmaceutical compositions for prevention and treatment of melanoma containing the same as active ingredients. The novel imidazole derivatives or pharmaceutically acceptable salts thereof according to the present invention have excellent inhibitory effects on various protein kinases, which cause melanoma, such as B-RAF, C-RAF, Aurora-A, BTK, Flt3, Ret, KDR/VEGFR2, P38α/MAPK14, RAF1, FMS, and the like, so they can be used for the prevention and treatment of melanoma.

Abstract translation: 本发明涉及新颖的咪唑衍生物或其药学上可接受的盐，其制备方法和用于预防和治疗含有与活性成分相同的黑素瘤的药物组合物。 根据本发明的新型咪唑衍生物或其药学上可接受的盐对各种蛋白激酶具有优异的抑制作用，其引起黑素瘤，例如B-RAF，C-RAF，Aurora-A，BTK，Flt3，Ret，KDR / VEGFR2 ，P38a / MAPK14，RAF1，FMS等，因此可用于预防和治疗黑素瘤。

公开(公告)号：WO2010064875A2

公开(公告)日：2010-06-10

申请号：PCT/KR2009/007247

申请日：2009-12-04

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY ,  KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY ,  SIM, Tae Bo ,  SON, Jung Beom ,  KIM, Hwan ,  PARK, Dong Sik ,  CHOI, Hwan Geun ,  HAM, Young Jin ,  HAH, Jung Mi ,  YOO, Kyung Ho ,  OH, Chang Hyun ,  LEE, So Ha ,  HA, Jae Du ,  CHO, Sung Yun ,  KWON, Byoung-Mog ,  HAN, Dong Cho

Inventor： SIM, Tae Bo ,  SON, Jung Beom ,  KIM, Hwan ,  PARK, Dong Sik ,  CHOI, Hwan Geun ,  HAM, Young Jin ,  HAH, Jung Mi ,  YOO, Kyung Ho ,  OH, Chang Hyun ,  LEE, So Ha ,  HA, Jae Du ,  CHO, Sung Yun ,  KWON, Byoung-Mog ,  HAN, Dong Cho

IPC: C07D231/56

CPC classification number: C07D413/14 ,  C07D231/56 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D407/04 ,  C07D409/04 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  C07D417/14

Abstract: Disclosed are novel indazole derivatives represented by the following Chemical Formula 1 or pharmaceutically acceptable salts, hydrates or solvates thereof, and pharmaceutical compositions for the prevention or treatment of proliferative diseases, containing the same as an active ingredient. Having potent inhibitory effect against protein kinase, such as b-raf, KDR, Fms, Tie2, SAPK2a and Ret, inducing diseases caused by abnormal cell proliferation, the novel indazole derivatives can be used for the prevention or treatment of diseases caused by abnormal cell proliferation.

Abstract translation: 公开了由以下化学式1表示的新型吲唑衍生物或其药学上可接受的盐，水合物或溶剂化物，以及用于预防或治疗增殖性疾病的药物组合物，其含有作为活性成分的药物组合物。 新型吲唑衍生物对b-raf，KDR，Fms，Tie2，SAPK2a，Ret等蛋白激酶具有强效抑制作用，可诱导异常细胞增殖引起的疾病，可用于预防或治疗由异常细胞引起的疾病 增殖。

公开(公告)号：WO2010058867A1

公开(公告)日：2010-05-27

申请号：PCT/KR2008/006815

申请日：2008-11-19

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  LEE, Suyoun ,  JEONG, Jeung-hyun ,  CHEONG, Byung Ki ,  KIM, Won Mok ,  JEONG, Doo Seok

Inventor： LEE, Suyoun ,  JEONG, Jeung-hyun ,  CHEONG, Byung Ki ,  KIM, Won Mok ,  JEONG, Doo Seok

IPC: H01L41/113

CPC classification number: F03G7/065

Abstract: A microactuator includes a substrate whose one end is fixed; a phase change film which is deposited on the substrate and has a high phase change rate, high strain and high stress during phase change; a protective film deposited on the phase change film; and a current pulse supply unit for supplying thermal energy to induce the phase transition of the phase change film, wherein the other end of the substrate is moved due to changes of the volume and residual stress of the phase change film accompanied by the phase transition thereof. The phase change film is made of a chalcogenide phase change material.

Abstract translation: 微致动器包括其一端固定的基板; 相变膜沉积在基板上，相变时具有高相变率，高应变和高应力; 沉积在相变膜上的保护膜; 以及用于提供热能以引起相变膜的相变的电流脉冲供给单元，其中基板的另一端由于伴随其相变的相变膜的体积和残余应力的变化而移动 。 相变膜由硫族化物相变材料制成。

公开(公告)号：WO2010055959A1

公开(公告)日：2010-05-20

申请号：PCT/KR2008/006638

申请日：2008-11-11

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  HWANG, Kyo Seon ,  KIM, Tae Song ,  KIM, Sang Kyung ,  LEE, Sang Myung ,  LEE, Yoon Sik

Inventor： HWANG, Kyo Seon ,  KIM, Tae Song ,  KIM, Sang Kyung ,  LEE, Sang Myung ,  LEE, Yoon Sik

IPC: G01N33/53

CPC classification number: G01N33/54373

Abstract: Provided is a protein detection system using a micro-cantilever and based on immune responses, wherein the micro-cantilever shows significantly improved sensitivity to allow detection of a trace amount of biomolecule. To the micro-cantilever, sandwich immunoassay is applied, and the sandwich immunoassay uses a polyclonal antibody or silica nanoparticles having a monoclonal antibody bound thereto, so that variations in the output signals of the cantilever are amplified and the detection sensitivity is significantly improved. The system enables detection of disease specific antigen at several femtomolar levels, and makes it possible to detect a trace amount of protein related to diseases, particularly to cancers, with ease.

Abstract translation: 提供了使用微悬臂梁并基于免疫应答的蛋白质检测系统，其中微悬臂梁显示显着改善的灵敏度以允许检测微量的生物分子。 对微悬臂梁进行夹心免疫测定，夹心免疫测定使用结合有单克隆抗体的多克隆抗体或二氧化硅纳米粒子，扩大悬臂输出信号的变化，检测灵敏度明显提高。 该系统能够以几个摩尔体积水平检测疾病特异性抗原，并且可以容易地检测与疾病，特别是癌症相关的微量蛋白质。

公开(公告)号：WO2010038926A1

公开(公告)日：2010-04-08

申请号：PCT/KR2008/007810

申请日：2008-12-30

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  LEE, Joong Ho ,  PARK, Ji Hyung ,  YEOM, Ki Won

Inventor： LEE, Joong Ho ,  PARK, Ji Hyung ,  YEOM, Ki Won

IPC: G06F3/03

CPC classification number: G06F3/0421 ,  G06F3/0418 ,  G06F2203/04104

Abstract: Disclosed is an optical recognition user input device and method for recognizing user input that can prevent an error in recognition of plural touch points. A plurality of optical transmission/reception modules (T/R) are disposed around a touch panel including a plurality of pixels. Each of the optical T/R modules includes a light emitting unit and a light receiving unit. A controller controls operation of the optical T/R modules and calculates a user touch location on the touch panel based on an optical signal received by the light receiving unit.

Abstract translation: 公开了一种用于识别可以防止识别多个接触点的错误的用户输入的光学识别用户输入装置和方法。 多个光发送/接收模块（T / R）被布置在包括多个像素的触摸面板周围。 每个光学T / R模块包括发光单元和光接收单元。 控制器控制光学T / R模块的操作，并且基于由光接收单元接收的光信号来计算触摸面板上的用户触摸位置。

公开(公告)号：WO2010032901A1

公开(公告)日：2010-03-25

申请号：PCT/KR2008/006688

申请日：2008-11-13

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  OH, Chang Hyun ,  CHO, Jung Hyuck

Inventor： OH, Chang Hyun ,  CHO, Jung Hyuck

IPC: C07D403/06

CPC classification number: C07D413/10

Abstract: Novel oxazolidinone derivatives with a difluorophenyl moiety, represented by Chemical Formula 1, pharmaceutically acceptable salts thereof, a preparation method thereof, and a pharmaceutical composition comprising the same as an active ingredient are provided. Exhibiting potent inhibitory activity against Gram-positive bacteria including Haemophilus influenza and Coagulase negative staphylococci and resistant bacteria including vancomycin-resistant en- terococci (VRE), the pharmaceutical composition is useful as an antibiotic.

Abstract translation: 提供了具有由化学式1表示的二氟苯基部分的新型恶唑烷酮衍生物，其药学上可接受的盐，其制备方法和包含其作为活性成分的药物组合物。 展示了抗革兰氏阳性菌（包括嗜血杆菌流感和凝固酶阴性葡萄球菌）和抗万古霉素耐药细菌（VRE）的抑制活性，药物组合物可用作抗生素。

公开(公告)号：WO2010002084A1

公开(公告)日：2010-01-07

申请号：PCT/KR2008/007898

申请日：2008-12-31

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  KIM, Il-Doo ,  HONG, Jae-Min

Inventor： KIM, Il-Doo ,  HONG, Jae-Min

IPC: H01M4/02

CPC classification number: H01M4/131 ,  H01M4/1391 ,  H01M4/364 ,  H01M4/48 ,  H01M4/661 ,  H01M10/052 ,  H01M2004/021

Abstract: There are provided an anode for a secondary battery having a negative active material with a multi-component metal oxide nanofiber web structure in which a cycle characteristic and a life characteristic are improved and stability is improved when charging and discharging are performed by a large current, a secondary battery using the same, and a method of fabricating a negative active material for a secondary battery. The method of fabricating the negative active material for a secondary battery includes spinning a solution in which no less than two kinds of metal-salt precursors and a polymer are mixed with each other onto an anode colector to form a web of composite fiber in which the no less than two kinds of metal-salt precursors and the polymer are mixed with each other, performing a thermal compression or thermal pressure process on the web of the composite fiber, and performing thermal treatment on the thermal compressed or thermal pressed web of the composite fiber to remove the polymer from the web of the composite filder.

Abstract translation: 提供一种具有负极活性物质的二次电池用阳极，其具有多组分金属氧化物纳米纤维网状结构，其中循环特性和寿命特性得到改善，并且通过大电流进行充电和放电时稳定性得到改善， 使用该二次电池的二次电池，以及二次电池的负极活性物质的制造方法。 制造二次电池用负极活性物质的方法包括将不少于两种金属盐前体和聚合物彼此混合的溶液旋转到阳极电极上，以形成复合纤维网，其中 将不少于两种金属盐前体和聚合物彼此混合，对复合纤维网幅进行热压或热压加工，并对复合材料的热压或热压网进行热处理 纤维从聚合物丝网的网上除去聚合物。