Abstract:
본발명은콜라겐가수분해물을유효성분으로포함하여필러의효능을장기간유지시키는비경구조성물에관한것이다. 본발명에의한조성물은히알루론산필러효능을보다장시간유지시킬수 있으므로, 보다적은횟수로필러를시술하여도그 효과가유지될수 있어서피부자극역시줄어든다는장점이있다. 아울러비경구투여로투여방법이간단하고피부에직접적으로침투할수 있어서, 즉각적인효과가가능하다는장점이있다.
Abstract:
본 발명은 PPAR-δ 활성 촉진 물질, AMPK 활성 촉진 물질 및 PGC1-α 활성 촉진 물질을 유효 성분으로 포함하는 근육 타입 변화 촉진, 근육량 증가, 근육 강화, 운동 능력 향상, 지질 감소, 지질 축적 억제, 혈당 감소, 체중 조절 또는 체중 감소용 조성물을 제공한다.
Abstract:
PURPOSE: A method for manufacturing a furofuran lignan compound is provided to selectively manufacture (+)-furofuran lignan and (-)-furofuran lignan, which is an optical isomer thereof. CONSTITUTION: A method for manufacturing a furofuran lignan compound comprises the step of O-alkylating one selected from a compound in Chemical Formula 1 and an optical isomer thereof. The furofuran lignan compound comprises a compound in Chemical Formula 7 or 8. The optical isomer of the compound in Chemical Formula 1 is manufactured by a reaction of a compound in Chemical Formula 11 and (+)-diisopropyltryptamine (DIPT) or (-)-DIPT.
Abstract:
PURPOSE: A composition containing a Camellia sinensis leaf extract, a Camellia sinensis flower extract, and a Camellia sinensis seed extract as active ingredients is provided to activate AMP-activated protein kinase (AMPK), to suppress fatty acid synthesis, and to promote fatty acid oxidation and glucose absorption, thereby preventing and treating metabolic syndrome. CONSTITUTION: A composition for preventing or treating metabolic syndrome contains a Camellia sinensis leaf extract, a Camellia sinensis flower extract, and a Camellia sinensis seed extract as active ingredients, in a weight ratio of 4-12:0.3-4:0.3-4. The composition contains the Camellia sinensis leaf extract and the Camellia sinensis flower and seed extracts in a weight ratio of 4-12:0.2-8. The metabolic syndrome is a glucoside metabolic syndrome or a lipid metabolic syndrome. The metabolic syndrome includes one or more among obesity, hyperlipidemia, type 2 diabetes, arteriosclerosis, myocardial infarction, and angina pectoris. The composition is a pharmaceutical composition. [Reference numerals] (AA) Mixture of Camellia sinensis leaf, flower, and seed extracts; (BB) Camellia sinensis flower extract; (CC) Camellia sinensis seed extract; (DD) Camellia sinensis leaf extract
Abstract:
PURPOSE: A composition containing syringaresinol for suppressing aging is provided to enhance SIRT1 expression, to suppress MMP-9 expression and collagen decomposition, and to improve anti-wrinkling. CONSTITUTION: A composition for anti-aging contains 1-80wt% of syringaresinol as an active ingredient. Syringaresinol is contains in one or more extracts selected from a lindseed extract, a Phellodendri cortex extract, an Acanthopanacis cortex extract, a sesame extract, and a ginseng fruit extract. Syringaresinol is prepared using one or more selected from the group consisting of water, an organic solvent, and a mixture thereof. The composition promotes SIRT1(sirtuin 1) expression.
Abstract:
PURPOSE: A composition containing syringaresinol as an active ingredient is provided to suppress melanogenesis and tyrosinase activity, and to ensure anti-oxidation and skin whitening. CONSTITUTION: A composition for skin whitening contains 0.001-20wt% of syringaresinol as an active ingredient. The composition enhances the brightness and uniformity of skin color. The composition treats hyperpigmentation. The hyperpigmentation includes melasma, seborrheic keratosis, freckle, nevus, and dark circle. Syringaresinol is contained in an extract selected among a lindseed extract, a Phellodendri cortex extract, an Acanthopanacis cortex extract, a sesame extract, and a ginseng fruit extract. The composition is used for removing dead skin cells and promotes dead skin cell turn over. [Reference numerals] (AA) Syringaresinol
Abstract:
PURPOSE: A composition containing syringaresinol for suppressing aging of blood vessels is provided to enhance SIRT 1 expression in vascular cells, to activate telomerase, and to suppress aging of blood vessel. CONSTITUTION: A composition for suppressing aging of blood vessel contains syringaresinol as an active ingredient. The composition is used for preventing or treating cardiovascular diseases such as cerebral infarction, cerebral hemorrhage, ischemic heart disease, myocardial infarction, and arteriosclerosis. Syringaresinol is contained in extracts selected among a linseed extract, a Phellodendri cortex extract, an Acanthopanax sessiliflorum extract, a sesame extract, and a ginseng fruit extract. [Reference numerals] (AA) Syringaresinol
Abstract:
PURPOSE: A composition containing syringaresinol for treating immune diseases is provided to promote SIRT 1 expression in immunocytes and differentiation to type 2 immunocytes, and to prevent or treat immune diseases. CONSTITUTION: A composition for preventing or treating immune diseases contains 1-80 wt% of syringaresinol as an active ingredient. The immune diseases include one or more among allergy, atopic dermatitis, hay fever, and rheumatoid arthritis. Syringaresinol is contained in one or more extracts selected among a linseed extract, a Phellodendri cortex extract, a sesame extract, and a ginseng fruit extract. [Reference numerals] (AA) MRNA of SIRT1 compared to a control group; (BB) 20uM syringaresinol; (CC) 50uM syringaresinol; (DD) 100uM syringaresinol