公开(公告)号：US09370613B2

公开(公告)日：2016-06-21

申请号：US14395337

申请日：2013-07-17

Applicant: Po-Lin Hsu ,  Ulrich Steinseifer ,  Jack Parker ,  Ruediger Autschbach

Inventor： Po-Lin Hsu ,  Ulrich Steinseifer ,  Jack Parker ,  Ruediger Autschbach

IPC: A61M1/12 ,  A61M1/10 ,  A61F2/82

CPC classification number: A61M1/125 ,  A61F2/82 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/102 ,  A61M1/1024 ,  A61M1/1029 ,  A61M1/1031 ,  A61M1/1036 ,  A61M1/122 ,  A61M2205/04 ,  A61M2205/103 ,  A61M2210/12

Abstract: An axial-flow blood pump has a rotatable impeller assembly rotatable about an axis and itself having a radially projecting blade and permanent magnets, A stationary stator assembly has stator windings interacting with the permanent magnets and a bearing system supporting the rotatable impeller assembly for rotation about the axis relative to the stator assembly. A stent implantable into a blood vessel is connected to ends of supports for coaxially mounting the stator assembly carrying the impeller assembly in the stent.

Abstract translation: 轴向血液泵具有可旋转的叶轮组件，其可以围绕轴线旋转并且本身具有径向突出的叶片和永磁体。固定定子组件具有与永磁体相互作用的定子绕组和支撑可旋转叶轮组件以便围绕 相对于定子组件的轴线。 可植入血管的支架连接到支撑件的端部，以将承载叶轮组件的定子组件同轴地安装在支架中。

公开(公告)号：US20160144087A1

公开(公告)日：2016-05-26

申请号：US14936980

申请日：2015-11-10

Applicant: VADOVATIONS, INC.

Inventor： Richard Wampler

IPC: A61M1/10

CPC classification number: A61M1/1017 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/102 ,  A61M1/1022 ,  A61M1/1031 ,  A61M1/1036 ,  A61M1/122 ,  A61M1/125

Abstract: A heart assist device comprising a rotary pump housing having a cylindrical bore, a pumping chamber and a motor stator including an electrically conductive coil located within the housing and surrounding a portion of the cylindrical bore. A rotor has a cylindrical shaft, at least one impeller appended to one end of the shaft, and a plurality of magnets located within the shaft. The rotor shaft is positioned within the housing bore with the magnets opposite the motor stator, and the impeller is positioned within the pumping chamber. The housing bore is closely fitted to the outer surface of the shaft forming a hydrodynamic journal bearing, with the pumping chamber and journal bearing connected by a leak path of blood flow between the pumping chamber and the journal bearing. A backiron of the motor stator attracts the rotor magnets to resist longitudinal displacement of the rotor within the housing during operation. The relative orientation of positions of the inflow, outflow, and leakage flow paths may be varied within the pump, such as to accommodate different intended methods for implantation and/or use.

公开(公告)号：US20160136344A1

公开(公告)日：2016-05-19

申请号：US15007005

申请日：2016-01-26

Applicant: MI-VAD, INC.

Inventor： Sudhir Kushwaha ,  Zain Khalpey

IPC: A61M1/12 ,  A61F2/82 ,  A61M1/10

CPC classification number: A61M1/125 ,  A61F2/82 ,  A61F2002/068 ,  A61F2210/009 ,  A61M1/1001 ,  A61M1/1005 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1018 ,  A61M1/1024 ,  A61M1/1031 ,  A61M1/1036 ,  A61M1/1086 ,  A61M1/1087 ,  A61M1/122 ,  A61M1/127 ,  A61M2205/0238 ,  A61M2205/04 ,  A61M2205/3303 ,  A61M2205/3507 ,  A61M2205/8206 ,  A61M2205/8243 ,  A61M2230/04

Abstract: A ventricular assist device includes a stent for placement within a cardiac artery and arranged for placement, the stent arranged to have an open configuration defining a flow path, a rotor sized to fit within the stent and arranged for percutaneous placement the flow path, the rotor including a surface disposed about a central portion and angled with respect to the flow path and having a first plurality of magnets. A collar is sized for placement about the cardiac artery and includes a stator. A power source is coupled to the stator, and the stator and the rotor are arranged to rotate the rotor about an axis. A timing control module controls a rotational speed of the rotor. Accordingly, the surface of the rotor is arranged to move blood along the flow path in response to rotation of the rotor.

公开(公告)号：US20150314059A1

公开(公告)日：2015-11-05

申请号：US14647861

申请日：2013-11-27

Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION ,  CARNEGIE MELLON UNIVERSITY

Inventor： William J. Federspiel ,  Brian Joseph Frankowski ,  James F. Antaki ,  Christian Andres Bermudez ,  Richard Garrett Jeffries ,  William R. Wagner

IPC: A61M1/36 ,  A61M1/32 ,  A61M1/10

CPC classification number: A61M1/3667 ,  A61M1/1006 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/1015 ,  A61M1/1029 ,  A61M1/1036 ,  A61M1/1698 ,  A61M1/262 ,  A61M1/267 ,  A61M1/32 ,  A61M2205/7536 ,  A61M2206/20

Abstract: A extracorporeal system for lung assist includes a housing, a blood flow inlet in fluid connection with the housing; a blood flow outlet in fluid connection with the housing; a plurality of hollow gas permeable fibers adapted to permit diffusion of gas between blood and an interior of the hollow gas permeable fibers, the plurality of hollow gas permeable fibers being positioned between the blood flow inlet and the blood flow outlet such that blood flows around the plurality of hollow gas permeable fibers when flowing from the blood flow inlet to the blood flow outlet; a gas inlet in fluid connection with the housing and in fluid connection with inlets of the plurality of hollow gas permeable fibers; a gas outlet in fluid connection with the housing and in fluid connection with outlets of the plurality of hollow gas permeable fibers; and at least one moving element to create velocity fields in blood flow contacting the plurality of hollow gas permeable fibers. The plurality of hollow gas permeable fibers may extend generally perpendicular to the direction of bulk flow of blood through the housing.

Abstract translation: 用于肺辅助的体外系统包括壳体，与壳体流体连接的血流入口; 与所述壳体流体连接的血流出口; 多个中空透气纤维，其适于允许血液和中空透气纤维内部之间的气体扩散，多个中空透气纤维位于血流入口和血流出口之间，使得血液围绕 当从血流入口流到血流出口时，多个中空透气纤维; 与所述壳体流体连接并与所述多个中空透气纤维的入口流体连接的气体入口; 与所述壳体流体连接并与所述多个中空透气纤维的出口流体连接的气体出口; 以及至少一个移动元件以在与多个中空透气纤维接触的血流中产生速度场。 多个中空透气纤维可以大致垂直于血液通过壳体的大量流动方向延伸。

公开(公告)号：US09133854B2

公开(公告)日：2015-09-15

申请号：US13617381

申请日：2012-09-14

Applicant: Atsushi Okawa ,  Takehisa Mori

Inventor： Atsushi Okawa ,  Takehisa Mori

IPC: F04D29/047 ,  A61M1/10 ,  F04D13/06 ,  F04D29/048

CPC classification number: F04D29/0473 ,  A61M1/1006 ,  A61M1/101 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1036 ,  A61M1/1055 ,  F04D13/06 ,  F04D13/0666 ,  F04D29/047 ,  F04D29/048

Abstract: A centrifugal blood pump device includes a housing, a centrifugal pump section having an impeller which rotates in the housing to send blood by centrifugal force upon rotation, an impeller rotation torque generation section for attracting a magnetic member of the impeller and rotating the impeller, and a plurality of grooves for hydrodynamic bearing provided on an inner face of the housing on the impeller rotation torque generation section side. A side wall of each of the grooves for hydrodynamic bearing is formed as an inclined side wall inclined obliquely such that the groove for hydrodynamic bearing is expanded from a bottom face of the groove for hydrodynamic bearing toward an opening face of the groove for hydrodynamic bearing.

Abstract translation: 一种离心式血液泵装置，包括壳体，具有叶轮的离心泵部分，所述叶轮在壳体中旋转以通过旋转时的离心力而发送血液;叶轮旋转扭矩产生部分，用于吸引叶轮的磁性部件并旋转叶轮;以及 多个用于流体动力轴承的槽，设置在壳体的叶轮旋转转矩产生部侧的内表面上。 每个用于流体动力轴承的槽的侧壁被形成为倾斜的侧壁，其倾斜地倾斜使得用于流体动力轴承的槽从用于流体动力轴承的槽的底面向流体动力轴承的槽的开口面扩展。

公开(公告)号：US20140322020A1

公开(公告)日：2014-10-30

申请号：US14328610

申请日：2014-07-10

Applicant: Thoratec Corporation

Inventor： Richard K. Wampler ,  David M. Lancisi

IPC: A61M1/10

CPC classification number: A61M1/1036 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1031 ,  A61M1/122 ,  F04D1/00 ,  F04D13/06 ,  F04D13/0666 ,  F04D29/0413 ,  F04D29/043 ,  F04D29/047 ,  F04D29/0473 ,  F04D29/048 ,  F04D29/22 ,  F04D29/426 ,  F04D29/628 ,  F16C32/044 ,  F16C2316/18 ,  Y10S415/90

Abstract: Various “contactless” bearing mechanisms including hydrodynamic, hydrostatic, and magnetic bearings are provided for a rotary pump as alternatives to mechanical contact bearings. These design features may be combined. In one embodiment, the pump apparatus includes a rotor having a bore, a ring-shaped upper rotor bearing magnet, and a ring-shaped lower rotor bearing magnet. The bearing magnets are concentric with the bore. The lack of mechanical contact bearings enables longer life pump operation and less damage to working fluids such as blood.

Abstract translation: 提供了用于旋转泵的各种“非接触”轴承机构，包括流体动力学，静液压和磁性轴承，作为机械接触轴承的替代品。 这些设计特征可以组合。 在一个实施例中，泵装置包括具有孔的转子，环形上转子轴承磁体和环形下转子轴承磁体。 轴承磁体与孔同心。 缺少机械接触轴承可以延长泵的运行寿命，减少对血液等工作流体的损坏。

公开(公告)号：US08790236B2

公开(公告)日：2014-07-29

申请号：US11992997

申请日：2006-06-02

Applicant: Jeffrey A. LaRose ,  Charles R. Shambaugh, Jr. ,  Richard A. Marquis ,  Daniel G. White ,  Palanivelu Thyagarajan

Inventor： Jeffrey A. LaRose ,  Charles R. Shambaugh, Jr. ,  Richard A. Marquis ,  Daniel G. White ,  Kartikeyan Trichi

IPC: A61M1/12

CPC classification number: A61M1/1036 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1029 ,  A61M1/1031 ,  A61M1/1086 ,  A61M1/122 ,  A61M1/125 ,  F04D3/02 ,  F04D29/0476

Abstract: An axial-flow blood pump for pumping blood includes a substantially cylindrical outer enclosure. A tubular housing concentric with and located within the outer enclosure has at one end an inlet and at an opposite end an outlet. A motor stator is concentric with and located between the outer enclosure and the tubular housing. An impeller is concentric with and located within the tubular housing. The impeller is suspended in operation by a combination of passive magnetic forces between magnets within the impeller or magnetized regions of the impeller and the motor stator and hydrodynamic thrust forces generated as blood flows between the tubular housing and a plurality of hydrodynamic thrust bearing surfaces located on the impeller. A volute may be in fluid-tight connection with the outlet of the tubular housing for receiving blood in the axial direction and directing blood in a direction normal to the axial direction. The volute has a flow-improving member extending axially from the volute and into and coaxially with the tubular housing.

Abstract translation: 用于泵送血液的轴流血泵包括基本上圆柱形的外壳。 与外壳同心并且位于外壳内的管状壳体在一端具有入口，在相对端具有出口。 电动机定子与外壳和管状壳体同心并位于外壳和管壳之间。 叶轮与管状壳体同心且位于管状壳体内。 叶轮悬挂在操作中，通过叶轮内的磁体或叶轮的磁化区域和电动机定子之间的无源磁力的组合以及当管状壳体和位于管状壳体之间的多个流体动力推力轴承表面时产生的流体动力推力 叶轮。 蜗壳可以与管状壳体的出口流体密封连接，用于在轴向方向上接收血液并且在垂直于轴向的方向上引导血液。 蜗壳具有从蜗壳轴向延伸并与管状壳体同轴的流动改进构件。

公开(公告)号：US08770945B2

公开(公告)日：2014-07-08

申请号：US13254979

申请日：2010-03-01

Applicant: Takayoshi Ozaki ,  Hiroyuki Yamada ,  Kenichi Suzuki ,  Ken Sugiura

Inventor： Takayoshi Ozaki ,  Hiroyuki Yamada ,  Kenichi Suzuki ,  Ken Sugiura

IPC: A61M1/10

CPC classification number: F04D25/026 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1031 ,  A61M1/1036 ,  A61M1/122 ,  F04D13/026 ,  F04D13/027 ,  F04D13/0666 ,  F04D17/10 ,  F04D29/048

Abstract: In this centrifugal blood pump apparatus, one permanent magnet is provided in one surface of an impeller, a second permanent magnet is provided in an inner wall of a blood chamber, a third permanent magnet is provided in the other surface of the impeller, and a fourth permanent magnet and a rotor for driving the impeller to rotate are provided, with an diaphragm being interposed. An amount of change in attractive force between the first permanent magnet and the second permanent magnet and an amount of change in attractive force between the third and fourth permanent magnets when the impeller is eccentric are made substantially equal to each other. Therefore, a levitation position of the impeller can always be maintained at a substantially central position in a housing.

Abstract translation: 在该离心式血液泵装置中，在叶轮的一个表面设置有一个永磁体，在血液室的内壁设置有第二永久磁铁，在叶轮的另一面设有第三永久磁铁， 第四永磁体和用于驱动叶轮旋转的转子设置有隔膜。 当叶轮偏心时，第一永磁体和第二永磁体之间的吸引力的变化量和第三和第四永磁体之间的吸引力变化量基本相等。 因此，叶轮的悬浮位置总能保持在壳体的大致中心位置。

公开(公告)号：US20140155998A1

公开(公告)日：2014-06-05

申请号：US14083752

申请日：2013-11-19

Applicant: Richard Wampler

Inventor： Richard Wampler

IPC: A61M1/10

CPC classification number: A61M1/1036 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1031 ,  A61M1/1086 ,  A61M1/12 ,  A61M1/122 ,  A61M2205/3334

Abstract: A total artificial heart having a rotor with an impeller, wherein the rotor is mounted within a pump housing on a hollow shaft. The rotor is magnetically driven to produce rotary motion of the impeller for pumping blood. The motor is disposed within the pump housing such that axial translation within the housing acts as a shuttle valve to alternate flow between pulmonary and systemic circulation.

Abstract translation: 具有带叶轮的转子的总人造心脏，其中转子安装在泵壳体中的空心轴上。 转子被磁力驱动以产生用于泵送血液的叶轮的旋转运动。 电动机设置在泵壳体内，使得壳体内的轴向平移作为梭阀来交换肺和全身循环之间的流动。

公开(公告)号：US20130338559A1

公开(公告)日：2013-12-19

申请号：US13968070

申请日：2013-08-15

Applicant: NOVITA THERAPEUTICS, LLC

Inventor： F. NICHOLAS FRANANO ,  Howard M. Loree, II ,  Geoff Tansley ,  Steve Woodard ,  Barrett Hutto

IPC: A61M1/10

CPC classification number: A61M1/101 ,  A61M1/1008 ,  A61M1/1012 ,  A61M1/1013 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1031 ,  A61M1/1036 ,  A61M1/1086 ,  A61M1/12 ,  A61M1/122 ,  A61M1/3653 ,  A61M1/3655 ,  A61M5/14236 ,  A61M2205/32 ,  A61M2205/3334 ,  F04D29/0462 ,  F04D29/0465 ,  F04D29/0566 ,  Y10S415/90

Abstract: The present invention relates to a rotary blood pump with a double pivot contact bearing system with an operating range between about 50 mL/min and about 1500 mL/min is described, wherein the force on the upper bearing is less than 3N during operating speeds up to 6000 rpm. The invention also relates to a method of using a blood pump system for persistently increasing the overall diameter and lumen diameter of peripheral veins and arteries by persistently increasing the speed of blood and the wall shear stress in a peripheral vein or artery for period of time sufficient to result in a persistent increase in the overall diameter and lumen diameter of the vessel is provided. The blood pump system may also be used to reduce venous hypertension in a lower extremity and increasing the rate of healing of lower extremity venous ulcers in patients is provided. The blood pump system includes a blood pump, blood conduit(s), a control system with optional sensors, and a power source. The pump system is configured to connect to the vascular system in a patient and pump blood at a desired rate. The pumping of blood is monitored and adjusted, as necessary, to maintain the desired elevated blood speed and wall shear stress, and the desired pulsatility in the target artery or vein in order to optimize the rate and extent of the persistent increase in the overall diameter and lumen diameter of the target peripheral artery or vein or to result in a reduction in venous blood pressure in the treated lower extremity or healing of the lower extremity venous ulcer.

Abstract translation: 本发明涉及具有操作范围在约50mL / min至约1500mL / min之间的双重枢轴接触轴承系统的旋转式血液泵，其中在操作加速期间上轴承上的力小于3N 至6000转/分。 本发明还涉及一种使用血液泵系统持续增加外周静脉和动脉的总直径和内腔直径的方法，其通过持续增加外周静脉或动脉中的血液速度和壁剪切应力足够长的时间 导致容器的总直径和管腔直径的持续增加。 血泵系统也可用于减少下肢静脉高血压，提高患者下肢静脉溃疡愈合率。 血液泵系统包括血液泵，血液导管，具有可选传感器的控制系统和电源。 泵系统被配置为连接到患者中的血管系统并以期望的速率泵血。 根据需要监测和调整血液的抽吸，以保持所需的升高的血液速度和壁剪切应力以及目标动脉或静脉中所需的搏动，以优化总体直径持续增加的速率和程度 和目标周围动脉或静脉的管腔直径，或导致治疗下肢静脉血压降低或下肢静脉溃疡愈合。