公开(公告)号：JP2009114213A

公开(公告)日：2009-05-28

申请号：JP2009048628

申请日：2009-03-02

Applicant: Alcon Inc ,  アルコン,インコーポレイテッド

Inventor： CASTILLO ERNESTO J ,  HAN WESLEY WEHSIN ,  ZHANG HUIXIANG ,  BHAGAT HARESH G ,  SINGH ONKAR N ,  BULLOCK JOSEPH PAUL ,  DIXIT SURESH C

IPC: A61K9/08 ,  A61K31/335 ,  A61K9/00 ,  A61K47/32 ,  A61K47/36 ,  A61K47/38 ,  A61K47/46 ,  A61P11/02 ,  A61P27/14 ,  A61P29/00 ,  A61P37/08

CPC classification number: A61K9/0043 ,  A61K9/0048 ,  A61K31/335 ,  A61K47/32 ,  Y10S514/912

Abstract: PROBLEM TO BE SOLVED: To provide a topical formulation of olopatadine for treatment of allergic or inflammatory disorders of the eye and nose.
SOLUTION: The aqueous formulations of this invention contain approximately 0.17 to 0.62%(w/v) of olopatadine and an amount of polyvinyl pyrrolidone or polystyrene sulfonic acid sufficient to enhance the physical stability of the formulation. The solution composition that can topically be administered for treatment of allergic or inflammatory disorders of eyes or noses is disclosed and the composition includes approximately 0.17 to 0.62%(w/v) of olopatadine and an amount of polyvinyl pyrrolidone or polystyrene sulfonic acid sufficient to enhance the physical stability of the formulation.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供用于治疗眼睛和鼻子的过敏或炎性疾病的奥洛他定的局部制剂。 解决方案：本发明的水性制剂含有约0.17至0.62％（w / v）的奥洛他定和一定量的聚乙烯吡咯烷酮或聚苯乙烯磺酸，足以增强制剂的物理稳定性。 公开了可以局部施用以治疗眼睛或眼睛过敏性或炎症性疾病的溶液组合物，其组成包括约0.17至0.62％（w / v）的奥洛他定和一定量的聚乙烯吡咯烷酮或聚苯乙烯磺酸，其足以增强 制剂的物理稳定性。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2009082724A

公开(公告)日：2009-04-23

申请号：JP2008257734

申请日：2008-10-02

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： HONG XIN ,  ZHANG XIAOXIAO

IPC: A61F2/16

CPC classification number: G02B3/0081 ,  A61F2/1632 ,  A61F2/1637 ,  A61F2/1648

Abstract: PROBLEM TO BE SOLVED: To provide an ophthalmologic lens capable of having variation of spherical power, and variation of spherical aberration. SOLUTION: In one embodiment, the two-element ophthalmologic lens is composed in such a way that lateral shift of two elements in mutual relation can cause both variation of spherical power provided by the lens and variation of spherical aberration provided by the lens. In some other embodiments, thickness profile of the two elements is designed in such a way that variation of the spherical aberration is in positive relation with variation of the spherical power of the lens. COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供能够具有球面光焦度变化和球面像差变化的眼科镜片。 解决方案：在一个实施例中，双元件眼科镜片以这样的方式组成，使得两个相互关系的元件的横向偏移可以导致透镜提供的球面光焦度的变化和由透镜提供的球面像差的变化 。 在一些其他实施例中，两个元件的厚度轮廓被设计成使得球面像差的变化与透镜的球面光焦度的变化成正相关。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2009066388A

公开(公告)日：2009-04-02

申请号：JP2008069802

申请日：2008-03-18

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： ATTINGER JUERG

IPC: A61F9/007 ,  A61B17/34

CPC classification number: A61B17/3421 ,  A61F9/00736

Abstract: PROBLEM TO BE SOLVED: To provide an ophthalmic cannula which permits curved instruments to be inserted into a surgical site. SOLUTION: The cannula has a tube that is longitudinally open along the entire, or along substantially the entire, length of the tubing. In the same way, attached to a proximal end of the tubing is a hub that is also longitudinally open. The hub acts as a stop to prevent the entire cannula from entering a surgical incision site. COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供允许弯曲的器械插入外科手术部位的眼科插管。 解决方案：套管具有沿着管的整个长度或基本上整个长度纵向打开的管。 以相同的方式，连接到管的近端是也是纵向打开的毂。 轮毂作为阻止整个套管进入手术切口部位的止挡部。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2009045461A

公开(公告)日：2009-03-05

申请号：JP2008208645

申请日：2008-08-13

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： BOUKHNY MIKHAIL ,  BOTT STEVEN

IPC: A61F9/007 ,  A61F2/16

CPC classification number: A61F2/16 ,  A61B3/107 ,  A61F2/1645 ,  A61F2/1662

Abstract: PROBLEM TO BE SOLVED: To provide a system and a method usable to prepare for proper selection and centering of an intraocular lens (IOL) functionally taking the place of a lens whose transparency is deteriorated. SOLUTION: An image of an eye, which may be captured during pre-operative tests and provided to a program operable to calculate the power and axis orientation of the IOL, is used to determine the location and orientation of the IOL. This produces a placement guide used to properly center and orient an IOL within the eye. COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供一种系统和方法，其可用于准备正确选择和定心的眼内透镜（IOL），以代替透明度降低的透镜。 解决方案：可以在术前测试中捕获并提供给可操作以计算IOL的功率和轴取向的程序的眼睛图像来确定IOL的位置和取向。 这产生一个放置指南，用于使IOL在眼睛内部适当地居中和定位。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2008203244A

公开(公告)日：2008-09-04

申请号：JP2007330558

申请日：2007-12-21

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： GAO SHAWN X ,  WILLIAMS DAVID LLOYD ,  ROWE T SCOTT ,  AGAHI DARYUSH

IPC: G01F23/28 ,  A61F9/007

CPC classification number: A61M1/0023 ,  A61F9/00736 ,  A61M2205/3306 ,  A61M2205/3389 ,  G01F23/2921

Abstract: PROBLEM TO BE SOLVED: To provide even and parallel light curtain to solve the problem wherein a linear light source of high-resolution optical liquid level for continuous monitoring of a system generally uses high-diffusion LED array, in order to achieve even light intensity, as a result, it will have a very large visual angle that the rays, i.e., light beams no longer become parallel. SOLUTION: The point source is located on focal point of parabolic reflector to illuminate the parabolic reflector. The parabolic reflector reflects light from the point source to generate parallel light curtain. This parallel light curtain becomes parallel to the symmetric axis of the parabolic reflector, to illuminate ophthalmic surgery chamber for storing fluid. Sensor array, combined with the chamber, detects the parallel light curtain for illuminating the chamber and supplies an output to a sensing, processing, control system in order to determine the liquid level of the chamber. This optical method for determining the liquid level of surgical fluid has the advantage of preventing surgical fluid from physical contamination. COPYRIGHT: (C)2008,JPO&INPIT

Abstract translation: 要解决的问题：为了提供均匀和平行的光幕来解决用于连续监视系统的高分辨率光学液位的线性光源通常使用高扩散LED阵列的问题，以便实现均匀 因此，光强度将会有非常大的视角，即光束即光束不再平行。 解决方案：点源位于抛物面反射器的焦点上，以照射抛物面反射器。 抛物面反射器反射来自点源的光以产生平行光幕。 该平行光幕变得平行于抛物面反射器的对称轴，以照射眼科手术室以存储流体。 传感器阵列与腔室结合，检测平行光幕以照射腔室，并将输出提供给感测，处理，控制系统，以确定腔室的液位。 这种用于确定手术液体的液位的光学方法具有防止手术液体物理污染的优点。 版权所有（C）2008，JPO＆INPIT

公开(公告)号：JP2008183407A

公开(公告)日：2008-08-14

申请号：JP2008017925

申请日：2008-01-29

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： ATTINGER JUERG

IPC: A61F9/007

CPC classification number: A61F9/00736 ,  A61B2017/320008

Abstract: PROBLEM TO BE SOLVED: To provide a membrane scraper, which specifically affords a greater visibility to a surgeon in posterior ophthalmic surgery. SOLUTION: The membrane scraper comprises a handle and a cannula attached to the handle. The cannula contains a snare or loop of a metal or polymer wire that can be either of a fixed length or adjustable/retractable. At least a portion of the loop is roughened, either by roughening the loop material itself, or by coating the loop with an abrasive material, such as diamond power or similar abrasive material. COPYRIGHT: (C)2008,JPO&INPIT

Abstract translation: 要解决的问题：提供一种膜刮刀，其特别地为后眼手术中的外科医生提供更大的可视性。 解决方案：膜刮刀包括手柄和附接到手柄的套管。 套管包含可以是固定长度或可调整/可缩回的金属或聚合物线的圈套或环。 环路的至少一部分被粗糙化，通过使环材料本身变粗糙，或者通过用研磨材料（例如金刚石动力或类似的研磨材料）涂覆环。 版权所有（C）2008，JPO＆INPIT

公开(公告)号：JP2008149148A

公开(公告)日：2008-07-03

申请号：JP2007324535

申请日：2007-12-17

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： HOPKINS MARK ALAN ,  GAO SHAWN X

IPC: A61F9/007

CPC classification number: A61M1/0023 ,  A61M2205/12 ,  A61M2205/3389

Abstract: PROBLEM TO BE SOLVED: To provide an apparatus and method for controlling the flow of aspiration fluid in an aspiration chamber of a surgical cassette. SOLUTION: The aspiration chamber having an aspiration port 632 positioned at or close to the bottom of an aspiration chamber 624 is provided. When the aspiration fluid enters the aspiration chamber from below the fluid surface (e.g., from a port located at the bottom or on a sidewall close to the bottom), it does not create disturbance at the liquid/air interface and thus does not disturb continuous level sensing. Also, since the aspiration port is placed at or very close to the bottom of the aspiration chamber, the liquid inside the chamber can be fully used for sustained reflux and push priming. COPYRIGHT: (C)2008,JPO&INPIT

Abstract translation: 要解决的问题：提供一种用于控制手术盒的吸入腔中的吸入流体的流动的装置和方法。 解决方案：提供具有位于吸气室624的底部或接近抽吸室624的吸入口632的抽吸室。 当抽吸流体从流体表面下方（例如，位于底部或靠近底部的侧壁处）进入抽吸室时，它不会在液体/空气界面处产生干扰，因此不会干扰连续的 水平传感。 此外，由于吸入口位于或非常接近抽吸室的底部，所以室内的液体可以被充分地用于持续回流和推动启动。 版权所有（C）2008，JPO＆INPIT

公开(公告)号：JP2008114070A

公开(公告)日：2008-05-22

申请号：JP2007284900

申请日：2007-11-01

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： DAVIS SHERMAN G ,  MORGAN MICHAEL D ,  SORENSEN GARY P

IPC: A61F9/007 ,  A61B18/00

CPC classification number: A61M1/0084 ,  A61F9/00745 ,  A61M25/0023 ,  A61M25/0029 ,  A61M25/0032 ,  A61M2025/0035

Abstract: PROBLEM TO BE SOLVED: To provide a water pouring/sucking system which is easy and reliable to reduce the surge of a fluid body. SOLUTION: The water pouring/sucking system is an operation system having a water pouring line and a sucking line, wherein both the lines have different compliances or hardnesses from each other, and the water pouring line has a higher compliance than the sucking line. COPYRIGHT: (C)2008,JPO&INPIT

Abstract translation: 要解决的问题：提供一种容易且可靠地减少流体的喘振的浇水/吸水系统。 解决方案：浇水/吸水系统是具有浇水管线和吸水管线的操作系统，其中两条线路具有不同的一致性或硬度，并且水浇注线具有比吸吮线更高的顺应性 线。 版权所有（C）2008，JPO＆INPIT

公开(公告)号：JP2008086780A

公开(公告)日：2008-04-17

申请号：JP2007260063

申请日：2007-10-03

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： CHARLES STEVEN T

IPC: A61B19/00 ,  A61F9/007

CPC classification number: A61B90/36 ,  A61B2090/306

Abstract: PROBLEM TO BE SOLVED: To provide a wide-angle surgical illuminator for ophthalmology, not requiring high accuracy for manufacturing the surface of a lens used in the tip of the illuminator. SOLUTION: According to one embodiment, this gradient index surgical illuminator includes: a light source adapted to provide a light beam; an optical cable optically coupled to the light source for receiving and transmitting the light beam; a handpiece operably coupled to the optical cable; an optical fiber operably coupled to the handpiece and optically coupled to the optical cable for receiving and transmitting the light beam; an optical element including a gradient index lens, and optically coupled to the distal end of the optical fiber for receiving the light beam and transmitting the light beam to illuminate a surgical field; and a cannula, operably coupled to the handpiece, for housing and directing the optical fiber and the optical element. The optical element can be a small-gauge, divergent gradient index concave lens having a distal surface coincident with the distal end of the cannula. COPYRIGHT: (C)2008,JPO&INPIT

Abstract translation: 要解决的问题：为了提供用于眼科的广角手术照明器，不需要高精度来制造在照明器的顶端中使用的镜片的表面。 解决方案：根据一个实施例，该渐变折射率手术照明器包括：适于提供光束的光源; 光学耦合到光源的光缆，用于接收和传输光束; 可操作地耦合到光缆的手持件; 光纤，其可操作地耦合到所述手持件并光学耦合到所述光缆，用于接收和传输所述光束; 光学元件，包括梯度折射率透镜，并且光学耦合到光纤的远端，用于接收光束并透射光束照射外科视野; 以及可操作地联接到所述手持件的套管，用于容纳和引导所述光纤和所述光学元件。 光学元件可以是具有与插管的远端重合的远表面的小规格发散梯度折射率凹透镜。 版权所有（C）2008，JPO＆INPIT

公开(公告)号：JP2008055160A

公开(公告)日：2008-03-13

申请号：JP2007219949

申请日：2007-08-27

Applicant: Alcon Inc ,  アルコン,インコーポレイティド

Inventor： GAO SHAWN X ,  NAZARIFAR NADER

IPC: A61F9/007 ,  A61B19/00 ,  G01F1/66

CPC classification number: A61M1/0023 ,  A61M1/0025 ,  A61M2205/12 ,  A61M2205/3375 ,  A61M2205/3379

Abstract: PROBLEM TO BE SOLVED: To provide a surgical cassette having an acoustic air reflector. SOLUTION: A surgical cassette is provided which has a rigid fluid channel formed into a rigid plastic component or housing. The piezoelectric crystals of an ultrasonic flow meter are positioned on one side of the fluid channel. The side wall of the fluid channel opposite the piezoelectric crystals is exposed to fluid in the flow channel on its interior side and is exposed to ambient air on its exterior side. The interface between the wall and the air acts as an acoustic reflector for the action of the ultrasonic flow meter. COPYRIGHT: (C)2008,JPO&INPIT

Abstract translation: 要解决的问题：提供具有声学空气反射器的手术盒。 解决方案：提供一种手术盒，其具有形成为刚性塑料部件或壳体的刚性流体通道。 超声波流量计的压电晶体位于流体通道的一侧。 与压电晶体相对的流体通道的侧壁暴露于其内侧的流动通道中的流体，并在其外侧暴露于环境空气。 壁与空气之间的界面用作超声波流量计的作用的声反射器。 版权所有（C）2008，JPO＆INPIT