公开(公告)号：US20240207837A1

公开(公告)日：2024-06-27

申请号：US18390556

申请日：2023-12-20

Applicant: TECAN TRADING AG

Inventor： Philipp OTT ,  Adrian SAGER ,  Luca FREI

IPC: B01L3/02 ,  G01N35/10

CPC classification number: B01L3/0275 ,  G01N35/10 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2300/0681 ,  G01N2035/103

Abstract: A pipette tip adapter (1) is detachably connectable between a pipetting device (10) and a pipette tip (15). The pipette tip adapter has a body (2) with an interior compartment (7) for holding a liquid (18), a recess (3) entering into a part of the body (2) for detachably receiving a connector (11) of the pipetting device (10) and having a first opening (5) pneumatically connected with the interior compartment (7). The pipette tip adapter (1) further has a tube section (4) projecting from the pipette tip adapter (1) detachably securable with a pipette tip (15) and having a second opening (6) hydraulically connected with the interior compartment (7). The pipette tip adapter (1) may be used in an automated pipetting system (100). An automated pipetting system (100) having a pipette tip adapter (1) for preparing liquid reactions is also disclosed.

公开(公告)号：US20240198345A1

公开(公告)日：2024-06-20

申请号：US18591107

申请日：2024-02-29

Applicant: TECAN TRADING AG

Inventor： Manfred LANSING ,  Tobias SAWETZKI ,  Nicole EGGENHOFER

IPC: B01L3/00 ,  B01L9/00 ,  G01N21/59 ,  G01N21/64

CPC classification number: B01L3/5085 ,  B01L9/523 ,  G01N21/59 ,  G01N21/6452 ,  B01L2200/06 ,  B01L2200/142 ,  B01L2300/0829

Abstract: An incubation cassette is disclosed for reducing liquid evaporation from wells of a microplate. A frame has a central first opening surrounded by an inner wall having dimensions designed for the placement of a microplate therein and an outer wall which extends substantially parallel to the inner wall. The outer wall adjoins the inner wall via an intermediate bottom such that a liquid reservoir is formed thereby. The liquid reservoir surrounds the first central opening. At least a portion of the incubation cassette that forms the liquid reservoir has a transparent portion. A microplate reader has a housing and a transport support which can be pulled out of the housing. The transport support has a bearing surface for placement of a microplate having a plurality of wells or such an incubation cassette, and a controller adapted to control a method for reducing liquid evaporation from wells of the microplate.

公开(公告)号：US11719355B2

公开(公告)日：2023-08-08

申请号：US17276731

申请日：2019-09-20

Applicant: TECAN TRADING AG

Inventor： Philipp Ott

IPC: F16K37/00 ,  F16K31/06 ,  B01L3/02 ,  G01F11/12 ,  G01F13/00

CPC classification number: F16K31/0675 ,  B01L3/0293 ,  F16K37/0083 ,  G01F11/12 ,  G01F13/006 ,  B01L2400/0666

Abstract: A method for controlling a magnetic valve and particularly a method for dispensing and/or aspirating a volume of liquid as well as a corresponding dispenser/pipetting apparatus is disclosed. The method for controlling a magnetic valve has measuring a capacitance at the magnetic valve and determining a position of a plunger based on the measured capacitance. The method for dispensing or aspirating a volume of liquid has controlling a flow of a system fluid by a magnetic valve located between a pressure source and a dispenser/pipetting tip, dispensing or aspirating a volume of liquid through an exterior opening of the tip dependent on the flow of the system fluid, wherein controlling the flow and determining a flow time in dependence of the volume of liquid to be dispensed or aspirated, and controlling the magnetic valve is held open for the duration of the flow time.

公开(公告)号：US11565249B2

公开(公告)日：2023-01-31

申请号：US16954414

申请日：2018-12-12

Applicant: TECAN TRADING AG

Inventor： Philipp Ott

IPC: G01N35/10 ,  B01L3/02 ,  G01N11/04 ,  G01N13/02

Abstract: A pipetting apparatus having a pipette tube with a first end provided with an opening for aspirating and/or dispensing of a sample fluid and a second end operationally connected to a pressure generating means. The pipetting apparatus has at least one measuring unit adapted to determine at least one measurement value of the sample fluid based on the aspirating and/or dispensing of the sample fluid and to provide a sample fluid measurement signal representative thereof to an output of the measuring unit. The pipetting apparatus also has a control circuit operationally coupled to the output of the measuring unit and the input of the pressure generating means, the control circuit is configured to control said pressure generating device based on the sample fluid measurement signal.

公开(公告)号：US20220401958A1

公开(公告)日：2022-12-22

申请号：US17630037

申请日：2020-08-03

Applicant: TECAN TRADING AG

Inventor： Philipp OTT ,  Adrian SAGER ,  Lars Johan BRANDEN

IPC: B01L3/00 ,  B01L3/02

Abstract: A cover for a fluid container having an essentially plane cover plate for closing at least one opening of at least one fluid container and at least two ports, and each port has a through channel extending through the entire thickness of the cover plate and a fluid impermeable first membrane is arranged over the entire cross section of the through channel of the first port and an at least gas permeable second membrane is arranged over the entire cross section of the through channel of the second port is disclosed.

公开(公告)号：US11442260B2

公开(公告)日：2022-09-13

申请号：US16041922

申请日：2018-07-23

Applicant: TECAN TRADING AG

Inventor： Andreas Erlbacher ,  Markus Schürf ,  Josef Grassl ,  Alexander Kaser

IPC: G02B21/00 ,  G02B7/36 ,  G02B7/32 ,  G02B21/24 ,  G02B21/06 ,  G02B21/36

Abstract: A system 100 and method are provided for imaging a sample in a sample holder. For providing autofocus, a 2D pattern is projected onto the sample holder 050 via an astigmatic optical element 120. Image data 172 of the sample is acquired by an image sensor 140 via magnification optics 150. A difference in sharpness of the two-dimensional pattern in the image data is measured along a first axis and a second axis. Based on the difference, a magnitude and direction of defocus of the camera subsystem is determined with respect to the sample holder. This enables the sample holder, and thereby the sample, to be brought into focus in a fast and reliable manner.

公开(公告)号：US20220193684A1

公开(公告)日：2022-06-23

申请号：US17558764

申请日：2021-12-22

Applicant: TECAN TRADING AG

Inventor： Marina KNOPPKE ,  Sven PFLUMM ,  Claudio BOHLI

IPC: B01L9/00

Abstract: A receiving frame for a support plate for pipette tips that is formed from two opposing longitudinal walls and two opposing transverse walls, each has an upper side and a lower side and laterally enclose an interior space is disclosed. The upper sides of the longitudinal walls and transverse walls together form a circumferential support surface on which a support plate for pipette tips can be reversibly placed. The receiving frame has a footprint on the lower side of the longitudinal walls and the transverse walls.

公开(公告)号：US11298695B2

公开(公告)日：2022-04-12

申请号：US16309325

申请日：2017-07-19

Applicant: TECAN TRADING AG

Inventor： Philipp Ott

IPC: B01L3/02 ,  G01N35/10 ,  G01F23/263 ,  B01L3/00 ,  G01D5/241 ,  G01N35/00 ,  B01L9/00 ,  G01F22/00 ,  B25J9/16

Abstract: The present invention relates to pipette tips for connecting to a pipette tube of a pipetting device that is used for taking up and dispensing fluids. A pipette tip is shaped as a long tube that forms a pipette body with an opening on one of its ends and the other end is designed to connect to the pipette tube. The pipette tip is characterised in that it has an electrode as a volume measuring electrode of a measuring capacitor. The present invention further relates to pipetting devices with a pipette tip, methods for determining the volume of a fluid sample in such a pipette tip, methods for recognising such a pipette tip on a pipetting device, methods for producing such a pipette tip, uses for such a pipette tip and a set of pipette tips.

公开(公告)号：US20220099695A1

公开(公告)日：2022-03-31

申请号：US17476290

申请日：2021-09-15

Applicant: TECAN TRADING AG

Inventor： Remo Kälin ,  Christina Bauer ,  Thomas Kunz

IPC: G01N35/10

Abstract: A multichannel pipetting plate comprises a plurality of connectors arranged in a lattice; wherein each connector is fluidically connectable to a pipetting tip; wherein each connector comprises an interface at which a friction contact between the connector and a foot of the pipetting tip is established; wherein the interfaces of the connectors are arranged in different planes, such that, at least at a border region of the pipetting plate, along each row and along each column of the lattice, at least three consecutive interfaces are arranged in at least two different planes.

公开(公告)号：US11273449B2

公开(公告)日：2022-03-15

申请号：US16393737

申请日：2019-04-24

Applicant: TECAN TRADING AG

Inventor： Marina Knoppke

IPC: B01L9/00

Abstract: A storage box for plastic pipette tips that has a frame part with two longitudinal walls and two transverse walls that enclose an interior space laterally. The storage box has a support plate arranged on the upper side of the frame part with a large number of bearing openings that plastic pipette tips can be inserted. The storage box also includes a pipette tip contact piece on the underside of the frame part for contacting a plastic pipette tip inserted into one of the bearing openings.